Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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Organic reagents

Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.

After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.

8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.

Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.

Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.

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Structure:
Chemical Name:
(R)-2-Phenylpyrrolidine
CAS:
56523-47-8
MF:
C10H13N
Structure:
Chemical Name:
2,6-Di-tert-butyl-4-mercaptophenol
CAS:
950-59-4
MF:
C14H22OS
Structure:
Chemical Name:
(dimethyl)[3-thieno[2,3-c][2]benzothiepin-4(9H)-ylidenepropyl]ammonium chloride
CAS:
1154-12-7
MF:
C17H20ClNS2
Chemical Name:
Quaternary ammonium compounds, C12-18-alkyl(hydroxyethyl)dimethyl, chlorides
CAS:
85736-63-6
Structure:
Chemical Name:
tert-Butyl (Mesitylsulfonyl)oxycarbaMate
CAS:
36016-39-4
MF:
C14H21NO5S
Structure:
Chemical Name:
ethylbis(3-phenylpropyl)ammonium chloride
CAS:
5982-87-6
MF:
C20H28ClN
Structure:
Chemical Name:
naphthalene-1-diazonium tetrafluoroborate
CAS:
28912-93-8
MF:
C10H7BF4N2
Structure:
Chemical Name:
POTASSIUM BOROTARTRATE
CAS:
12001-68-2
MF:
C8H4B2O12.2K
Structure:
Chemical Name:
2-(4-Nitrophenyl)oxirane
CAS:
6388-74-5
MF:
C8H7NO3
Chemical Name:
Sulfonic acids, petroleum, calcium salts
CAS:
61789-86-4
Structure:
Chemical Name:
trichloro(N,N-dimethyloctylamine)boron
CAS:
34762-90-8
MF:
C10H23BCl3N
Structure:
Chemical Name:
3-BROMO-2-(3'-FLUOROBENZYLOXY)-5-METHYL&
CAS:
849062-40-4
MF:
C14H13BBrFO3
Structure:
Chemical Name:
4-(2'-CHLOROBENZYLOXY)-3,5-DIMETHYLPHEN&
CAS:
849052-15-9
MF:
C15H16BClO3
Structure:
Chemical Name:
Benzoic acid, 2-hexyl-4,6-dihydroxy-, methyl ester
CAS:
102342-63-2
MF:
C14H20O4
Structure:
Chemical Name:
4-(DIMETHYLCARBAMOYL)-3-FLUOROBENZENEBORONIC ACID
CAS:
874289-13-1
MF:
C9H11BFNO3
Structure:
Chemical Name:
3-CHLORO-2-HYDROXYPHENYL BORONIC ACID
CAS:
951655-50-8
MF:
C6H6BClO3
Structure:
Chemical Name:
2-(TERT-BUTOXYCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YLBORONIC ACID
CAS:
1312765-94-8
MF:
C14H20BNO4
Structure:
Chemical Name:
4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID
CAS:
886536-37-4
MF:
C8H8BF3O3
Structure:
Chemical Name:
2-(Benzyloxy)-4-methylpyridine-5-boronic acid
CAS:
1451391-35-7
MF:
C13H14BNO3
Structure:
Chemical Name:
2,6-Dimethyl-4-fluorophenylboronic acid
CAS:
1392512-54-7
MF:
C8H10BFO2
Structure:
Chemical Name:
5-Chloro-2-isopropoxypyridine-4-boronic acid
CAS:
1451391-05-1
MF:
C8H11BClNO3
Structure:
Chemical Name:
1-pinacolato-2-(1,8)diamo-naphthalenylborane
CAS:
1214264-88-6
MF:
C16H20B2N2O2
Structure:
Chemical Name:
(5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-4-yl)boronic acid
CAS:
2022976-34-5
MF:
C13H17BN2O3
Chemical Name:
mPEG36-Br
Structure:
Chemical Name:
(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)boronic acid
CAS:
913739-28-3
MF:
C6H14B2O4
Structure:
Chemical Name:
2-Fluoro-3-ethoxypyridine-5-boronic acid
CAS:
2121513-14-0
MF:
C7H9BFNO3
Structure:
Chemical Name:
B-(2'-bromo[1,1'-biphenyl]-2-yl)-Boronic acid,
CAS:
1089189-34-3
MF:
C12H10BBrO2
Structure:
Chemical Name:
5-HYDROXY-2-METHOXYPHENYLBORONIC ACID
CAS:
1072952-43-2
MF:
C7H9BO4
Structure:
Chemical Name:
Azetidine hydrochloride
CAS:
36520-39-5
MF:
C3H8ClN
Structure:
Chemical Name:
Sodium metaborate hydrate
CAS:
15293-77-3
MF:
BH2NaO3
Structure:
Chemical Name:
8-Methylquinoline-5-boronic Acid Pinacol Ester
CAS:
1366740-47-7
MF:
C16H20BNO2
Structure:
Chemical Name:
4-(TERT-BUTOXYCARBONYLAMINO)-3-METHOXYPHENYLBORONIC ACID, PINACOL ESTER
CAS:
262433-02-3
MF:
C18H28BNO5
Structure:
Chemical Name:
Benzyldodecyldimethylammonium Chloride Dihydrate
CAS:
147228-80-6
MF:
C21H42ClNO2
Structure:
Chemical Name:
3-(TRIFLUOROMETHYL)PHENYLTRIMETHYLAMMONIUM IODIDE
CAS:
27389-57-7
MF:
C10H13F3IN
Structure:
Chemical Name:
4-(bromoacetyl)-1,3-phenylene dimethyl biscarbonate
CAS:
1428451-07-3
MF:
C12H11BrO7
Structure:
Chemical Name:
2,3-DIHYDRO-1-BENZOFURAN-7-BORONIC ACID
CAS:
685514-61-8
MF:
C8H9BO3
Structure:
Chemical Name:
2-Methyl-6-cyanopyridine-4-boronic acid
CAS:
1443112-27-3
MF:
C7H7BN2O2
Structure:
Chemical Name:
DMT-dI Phosphoramidite
CAS:
141684-35-7
MF:
C40H47N6O7P
Structure:
Chemical Name:
5-(4 4 5 5-TETRAMETHYL-1 3 2-DIOXABOROL&
CAS:
479719-88-5
MF:
C14H17BO2S2
Structure:
Chemical Name:
3-Bromo-2-ethoxy-5-fluorophenylboronicacid
CAS:
352534-82-8
MF:
C8H9BBrFO3
Structure:
Chemical Name:
TRANS-1-PROPEN-1-YLBORONIC ACID
CAS:
7547-97-9
MF:
C3H7BO2
Structure:
Chemical Name:
1,3-BIS(2,4,6-TRIMETHYLPHENYL)IMIDAZOL-2-YLIDENE
CAS:
141556-42-5
MF:
C21H24N2**
Structure:
Chemical Name:
(4-borono-2,5-dimethylphenyl)boronic acid
CAS:
90085-60-2
MF:
C8H12B2O4
Structure:
Chemical Name:
Boronicacid,B,B'-thieno[3,2-b]thiophene-2,5-diylbis-
CAS:
1281324-46-6
MF:
C6H6B2O4S2
Structure:
Chemical Name:
Rhodium(1+), [(2,3,5,6-η)-bicyclo[2.2.1]hepta-2,5-diene][(1S,1'S,2S,2'S)-2,2'-bis(1,1-dimethylethyl)-2,2',3,3'-tetrahydro-1,1'-bi-1H-isophosphindole-κP2,κP2']-, tetrafluoroborate(1-) (1:1)
CAS:
953081-84-0
MF:
C31H38BF4P2Rh
Structure:
Chemical Name:
(4-Chloro-2-fluoro-5-formylphenyl)boronic acid
CAS:
325786-27-4
MF:
C7H5BClFO3
Structure:
Chemical Name:
4-METHOXYMETHYLBENZENEBORONIC ACID
CAS:
279262-11-2
MF:
C8H11BO3
Structure:
Chemical Name:
PYRAZOLO[1,5-A]PYRIDIN-7-YLBORONIC ACID
CAS:
1231934-40-9
MF:
C7H7BN2O2
Structure:
Chemical Name:
(N-HEXYL)TRIMETHYLAMMONIUM BROMIDE
CAS:
2650-53-5
MF:
C9H22BrN
Structure:
Chemical Name:
(+/-)8-HDOHE
CAS:
90780-54-4
MF:
C22H32O3
Structure:
Chemical Name:
9-METHOXYCANTHIN-6-ONE
CAS:
74991-91-6
MF:
C15H10N2O2
Structure:
Chemical Name:
TERT-BUTYL CIS-4-HYDROXYCYCLOHEXYLCARBAMATE
CAS:
167081-25-6
MF:
C11H21NO3
Structure:
Chemical Name:
CHEMBRDG-BB 4012533
CAS:
265664-52-6
MF:
C9H13BO4
Structure:
Chemical Name:
6-(4-Hydroxyphenoxy)hexyl acrylate
CAS:
161841-12-9
MF:
C15H20O4
Structure:
Chemical Name:
sodium tetrafluoroferrate(1-)
CAS:
15274-99-4
MF:
F4FeNa
Structure:
Chemical Name:
2-aminoethanol, monoester with boric acid
CAS:
10377-81-8
MF:
C2H8BNO3
Structure:
Chemical Name:
5-NITROACENAPHTHENE
CAS:
602-87-9
MF:
C12H9NO2
Structure:
Chemical Name:
5-Chloro-2-methyl-3-nitrophenylboronic acid
CAS:
957060-80-9
MF:
C7H7BClNO4
Structure:
Chemical Name:
5-Bromo-2-chloro-4-(trifluoromethyl)phenylboronicacid
CAS:
1452574-71-8
MF:
C7H4BBrClF3O2
Structure:
Chemical Name:
4,4-DIFLUORO-N-((1S)-3-OXO-1-PHENYLPROPYL)CYCLOHEXANE-1-CARBOXAMIDE
CAS:
376348-78-6
MF:
C16H19F2NO2
Structure:
Chemical Name:
(4-METHYL-PIPERAZINE-1-YL)-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-PHENYL]-METHANONE
CAS:
832114-06-4
MF:
C18H27BN2O3
Structure:
Chemical Name:
5-Trifluoromethyl-thiophene-2-boronic acid
CAS:
958451-91-7
MF:
C5H4BF3O2S
Structure:
Chemical Name:
CYCLOHEXYLDIMETHYLETHYL-AMMONIUM HYDROXIDE
CAS:
105197-93-1
MF:
C10H23NO
Structure:
Chemical Name:
2-METHYL-1-(METHYLAMINO)PROPAN-2-OL
CAS:
67622-86-0
MF:
C5H13NO
Structure:
Chemical Name:
Tris(hydroxymethyl)nitromethane
CAS:
126-11-4
MF:
C4H9NO5
Structure:
Chemical Name:
4-AMINOMETHYLPHENYLBORONIC ACID, PINACOL ESTER, HCL
CAS:
850568-55-7
MF:
C13H21BClNO2
Structure:
Chemical Name:
1H-Indole-1-carboxylic acid, 2-borono-6-fluoro-, 1-(1,1-dimethylethyl) ester
CAS:
1000068-26-7
MF:
C13H15BFNO4
Structure:
Chemical Name:
3-CHLORO-2-FLUOROPHENYLBORONIC ACID
CAS:
352535-82-1
MF:
C6H5BClFO2
Structure:
Chemical Name:
E-Crotylboronic acid pinacol ester, trans-2-(2-Buten-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS:
69611-02-5
MF:
C10H19BO2
Structure:
Chemical Name:
Potassium cyclohexylmethyltrilfuoroborate
CAS:
1346647-18-4
MF:
C7H12BF3K
Structure:
Chemical Name:
N-Methylbenzylamine
CAS:
103-67-3
MF:
C8H11N
Structure:
Chemical Name:
3-(TRIFLUOROMETHYL)PHENYLTRIMETHYLAMMONIUM BROMIDE
CAS:
262608-95-7
MF:
C10H13BrF3N
Structure:
Chemical Name:
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester
CAS:
7163-25-9
MF:
C13H12O3
Chemical Name:
Methanolic hydrochloric acid solution
Structure:
Chemical Name:
trans-4-Propylcyclohexanemethanol
CAS:
71458-06-5
MF:
C10H20O
Structure:
Chemical Name:
Dodecanamide
CAS:
112-01-6
MF:
C12H25NO
Structure:
Chemical Name:
3,4-Difluoro-2-methoxyphenylboronic acid
CAS:
905583-06-4
MF:
C7H7BF2O3
Structure:
Chemical Name:
2-Fluoro-6-methoxypyridin-3-ylboronic acid
CAS:
1402238-30-5
MF:
C6H7BFNO3
Structure:
Chemical Name:
1,2-Bis((2S,5S)-2,5-diisopropylphospholano)benzene(cyclooctadiene)rhodium(I) tetrafluoroborate, 97%
CAS:
1000393-36-1
MF:
C34H54BF4P2Rh
Structure:
Chemical Name:
4-Chloro-3-methoxyphenylboronic acid pinacolester
CAS:
627525-96-6
MF:
C13H18BClO3
Structure:
Chemical Name:
2-(Morpholin-4-yl)pyridin-3-ylboronic acid
CAS:
1218790-86-3
MF:
C9H13BN2O3
Structure:
Chemical Name:
OlMesartan DiMer Ester IMpurity
CAS:
1040250-19-8
MF:
C48H50N12O5
Structure:
Chemical Name:
Ethyl 5-broMo-4-pyriMidinecarboxylate
CAS:
64224-59-5
MF:
C7H7BrN2O2
Structure:
Chemical Name:
DiMethyldioctadecylaMMoniuM Iodide
CAS:
7206-39-5
MF:
C38H80IN
Structure:
Chemical Name:
CHEMBRDG-BB 4015829
CAS:
1287753-34-7
MF:
C10H11BN2O3
Structure:
Chemical Name:
3-Chloro-4-pyridineboronic acid hydrate
CAS:
1256355-22-2
MF:
C5H7BClNO3
Structure:
Chemical Name:
4-(1-(Methoxycarbonyl)cyclopropyl)phenylboronic acid
CAS:
1217501-08-0
MF:
C11H13BO4
Structure:
Chemical Name:
4-(3-CyanophenylMethoxy)phenylboronic acid
CAS:
1256355-78-8
MF:
C14H12BNO3
Structure:
Chemical Name:
Boronic acid, B-(2,3-dihydro-1H-indol-5-yl)-
CAS:
935853-24-0
MF:
C8H10BNO2
Structure:
Chemical Name:
(3-(ethoxyMethyl)phenyl)boronic acid
CAS:
1107603-49-5
MF:
C9H13BO3
Structure:
Chemical Name:
Cefepime Impurity A
CAS:
97164-57-3
MF:
C19H24N6O5S2
Structure:
Chemical Name:
2,4,6-Triformylphloroglucinol
CAS:
34374-88-4
MF:
C9H6O6
Structure:
Chemical Name:
N-Methyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-aMine
CAS:
1350913-08-4
MF:
C12H19BN2O2
Structure:
Chemical Name:
ICA-105574
CAS:
316146-57-3
MF:
C19H14N2O4
Structure:
Chemical Name:
ETHYL 1-CYANOCYCLOPROPANECARBOXYLATE
CAS:
1558-81-2
MF:
C7H9NO2
Structure:
Chemical Name:
2,2'-Dibromodiethyl ether
CAS:
5414-19-7
MF:
C4H8Br2O
Chemical Name:
Crystal violet Solution 10% in methanol
Structure:
Chemical Name:
5-Methoxy-2-formylphenylboronic acid
CAS:
40138-18-9
MF:
C8H9BO4
Structure:
Chemical Name:
Methyl 2-phenylacetoacetate
CAS:
16648-44-5
MF:
C11H12O3
Structure:
Chemical Name:
Amfonelic acid
CAS:
15180-02-6
MF:
C18H16N2O3