Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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Organic reagents

Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.

After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.

8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.

Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.

Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.

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Structure:
Chemical Name:
Diisopropyl malonate
CAS:
13195-64-7
MF:
C9H16O4
Structure:
Chemical Name:
2-Bromomethylphenylboronic acid
CAS:
91983-14-1
MF:
C7H8BBrO2
Structure:
Chemical Name:
2-Bromo-3-nitrotoluene
CAS:
41085-43-2
MF:
C7H6BrNO2
Structure:
Chemical Name:
Salicylaldoxime
CAS:
94-67-7
MF:
C7H7NO2
Structure:
Chemical Name:
TRIMETHYLENE DI(THIOTOSYLATE)
CAS:
3866-79-3
MF:
C17H20O4S4
Structure:
Chemical Name:
4-(4-Nitrophenyl)azoresorcinol
CAS:
74-39-5
MF:
C12H9N3O4
Structure:
Chemical Name:
Ethyl Succinyl Chloride
CAS:
14794-31-1
MF:
C6H9ClO3
Structure:
Chemical Name:
4-ISOPROPYL-3-THIOSEMICARBAZIDE
CAS:
13431-36-2
MF:
C4H11N3S
Structure:
Chemical Name:
5-Indoleboronic acid pinacol ester
CAS:
269410-24-4
MF:
C14H18BNO2
Structure:
Chemical Name:
Tetrabutylammonium phosphate
CAS:
5574-97-0
MF:
C16H38NO4P
Structure:
Chemical Name:
4-PYRIDYLTHIOUREA
CAS:
164670-44-4
MF:
C6H7N3S
Structure:
Chemical Name:
2-Amino-4-phenylbutane
CAS:
22374-89-6
MF:
C10H15N
Structure:
Chemical Name:
2,4-Dichlorophenylacetonitrile
CAS:
6306-60-1
MF:
C8H5Cl2N
Structure:
Chemical Name:
3,4,7,8-Tetramethyl-1,10-phenanthroline
CAS:
1660-93-1
MF:
C16H16N2
Structure:
Chemical Name:
4-Nitroanisole
CAS:
100-17-4
MF:
C7H7NO3
Structure:
Chemical Name:
3,5-DICHLOROPHENYLTHIOUREA
CAS:
107707-33-5
MF:
C7H6Cl2N2S
Structure:
Chemical Name:
Benzofuran-2-boronic acid
CAS:
98437-24-2
MF:
C8H7BO3
Structure:
Chemical Name:
METHYL OXALYL CHLORIDE
CAS:
5781-53-3
MF:
C3H3ClO3
Structure:
Chemical Name:
Fluorescein isothiocyanate isomer I
CAS:
3326-32-7
MF:
C21H11NO5S
Structure:
Chemical Name:
7-FLUOROBENZO-2-OXA-1,3-DIAZOLE-4-SULFONIC ACID AMMONIUM SALT
CAS:
84806-27-9
MF:
C6H6FN3O4S
Structure:
Chemical Name:
4-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-3-THIOSEMICARBAZIDE
CAS:
38901-31-4
MF:
C9H7F6N3S
Structure:
Chemical Name:
Diphenylcarbamyl chloride
CAS:
83-01-2
MF:
C13H10ClNO
Structure:
Chemical Name:
4,4'-THIODIANILINE
CAS:
139-65-1
MF:
C12H12N2S
Structure:
Chemical Name:
D-CAMPHOR
CAS:
464-49-3
MF:
C10H16O
Structure:
Chemical Name:
2-Fluoropropiophenone
CAS:
446-22-0
MF:
C9H9FO
Structure:
Chemical Name:
1,4,5,8-Naphthalenetetracarboxylic dianhydride
CAS:
81-30-1
MF:
C14H4O6
Structure:
Chemical Name:
1,2-Cyclohexanedicarboximide
CAS:
1444-94-6
MF:
C8H11NO2
Structure:
Chemical Name:
4-Bromoresorcinol
CAS:
6626-15-9
MF:
C6H5BrO2
Structure:
Chemical Name:
2-IODOBENZOYL CHLORIDE
CAS:
609-67-6
MF:
C7H4ClIO
Structure:
Chemical Name:
ETHYL PHENYL SULFIDE
CAS:
622-38-8
MF:
C8H10S
Structure:
Chemical Name:
3-Methylanisole
CAS:
100-84-5
MF:
C8H10O
Structure:
Chemical Name:
FCCP
CAS:
370-86-5
MF:
C10H5F3N4O
Structure:
Chemical Name:
4-Bromophenoxybenzene
CAS:
101-55-3
MF:
C12H9BrO
Structure:
Chemical Name:
1-Butylpyridinium bromide
CAS:
874-80-6
MF:
C9H14BrN
Structure:
Chemical Name:
Oxobutanedioic acid
CAS:
328-42-7
MF:
C4H4O5
Structure:
Chemical Name:
n-Butyl vinyl ether
CAS:
111-34-2
MF:
C6H12O
Structure:
Chemical Name:
2-PHENYL-2-PROPANOL
CAS:
617-94-7
MF:
C9H12O
Structure:
Chemical Name:
Triethylborane
CAS:
97-94-9
MF:
C6H15B
Structure:
Chemical Name:
Tulipalin A
CAS:
547-65-9
MF:
C5H6O2
Structure:
Chemical Name:
EUROPIUM TRIFLUOROMETHANESULFONATE
CAS:
52093-25-1
MF:
C3EuF9O9S3
Structure:
Chemical Name:
4-Biphenylcarboxaldehyde
CAS:
3218-36-8
MF:
C13H10O
Structure:
Chemical Name:
4-Ethylresorcinol
CAS:
2896-60-8
MF:
C8H10O2
Structure:
Chemical Name:
3-METHYL-1H-INDAZOLE
CAS:
3176-62-3
MF:
C8H8N2
Structure:
Chemical Name:
3-Fluorophthalic acid
CAS:
1583-67-1
MF:
C8H5FO4
Structure:
Chemical Name:
1-Phenyl-1,2-propanedione
CAS:
579-07-7
MF:
C9H8O2
Structure:
Chemical Name:
Methyl lactate
CAS:
547-64-8
MF:
C4H8O3
Structure:
Chemical Name:
3,4,5,6-TETRAHYDRO-2-PYRIMIDINETHIOL
CAS:
2055-46-1
MF:
C4H8N2S
Structure:
Chemical Name:
4-Isopropylphenol
CAS:
99-89-8
MF:
C9H12O
Structure:
Chemical Name:
1-(2-Pyridylazo)-2-naphthol
CAS:
85-85-8
MF:
C15H11N3O
Structure:
Chemical Name:
Trimethoxypropylsilane
CAS:
1067-25-0
MF:
C6H16O3Si
Structure:
Chemical Name:
1-Octyn-3-ol
CAS:
818-72-4
MF:
C8H14O
Structure:
Chemical Name:
beta-Methyl vinyl phosphate (MAP)
CAS:
90776-59-3
MF:
C29H27N2O10P
Structure:
Chemical Name:
Isobutylbenzene
CAS:
538-93-2
MF:
C10H14
Structure:
Chemical Name:
Phenethyl isocyanate
CAS:
1943-82-4
MF:
C9H9NO
Structure:
Chemical Name:
5,6,7,8-Tetrahydro-2-naphthol
CAS:
1125-78-6
MF:
C10H12O
Structure:
Chemical Name:
2-Acetamidophenol
CAS:
614-80-2
MF:
C8H9NO2
Structure:
Chemical Name:
2'-BROMO-4'-FLUOROACETOPHENONE
CAS:
1006-39-9
MF:
C8H6BrFO
Structure:
Chemical Name:
8-Bromooctanoic acid
CAS:
17696-11-6
MF:
C8H15BrO2
Structure:
Chemical Name:
Ethyl vinyl sulfone
CAS:
1889-59-4
MF:
C4H8O2S
Structure:
Chemical Name:
Padimate
CAS:
21245-01-2
MF:
C14H21NO2
Structure:
Chemical Name:
Lauric acid
CAS:
143-07-7
MF:
C12H24O2
Structure:
Chemical Name:
3-Aminobenzeneboronic acid hemisulfate salt
CAS:
66472-86-4
MF:
C12H18B2N2O8S
Structure:
Chemical Name:
4-Mercaptophenol
CAS:
637-89-8
MF:
C6H6OS
Structure:
Chemical Name:
AMINOGUANIDINE HYDROCHLORIDE
CAS:
16139-18-7
MF:
CH7ClN4
Structure:
Chemical Name:
4-(TRIFLUOROMETHYL)HYDROCINNAMIC ACID
CAS:
53473-36-2
MF:
C10H9F3O2
Structure:
Chemical Name:
3-Bromopyruvic acid
CAS:
1113-59-3
MF:
C3H3BrO3
Structure:
Chemical Name:
MTT
CAS:
2348-71-2
MF:
C18H16BrN5S
Structure:
Chemical Name:
Phenylfluorone
CAS:
975-17-7
MF:
C19H12O5
Structure:
Chemical Name:
Methyl 3-iodobenzoate
CAS:
618-91-7
MF:
C8H7IO2
Structure:
Chemical Name:
(TRIISOPROPYLSILYL)ACETYLENE
CAS:
89343-06-6
MF:
C11H22Si
Structure:
Chemical Name:
1-TERT-BUTYL-2-THIOUREA
CAS:
7204-48-0
MF:
C5H12N2S
Structure:
Chemical Name:
N,N'-DI-N-PROPYLTHIOUREA
CAS:
26536-60-7
MF:
C7H16N2S
Structure:
Chemical Name:
TRIMETHYLSILYL METHANESULFONATE
CAS:
10090-05-8
MF:
C4H12O3SSi
Structure:
Chemical Name:
4-Amino-3,5-dichloroacetophenone
CAS:
37148-48-4
MF:
C8H7Cl2NO
Structure:
Chemical Name:
3-ACETYLBENZONITRILE
CAS:
6136-68-1
MF:
C9H7NO
Structure:
Chemical Name:
2,3-DIHYDROBENZOFURAN-7-CARBOXYLIC ACID
CAS:
35700-40-4
MF:
C9H8O3
Structure:
Chemical Name:
2-Butene-1,4-diol
CAS:
6117-80-2
MF:
C4H8O2
Structure:
Chemical Name:
4-(Trifluoromethyl)phenylhydrazine hydrochloride
CAS:
2923-56-0
MF:
C7H8ClF3N2
Structure:
Chemical Name:
N-PROPYLTHIOUREA
CAS:
927-67-3
MF:
C4H10N2S
Structure:
Chemical Name:
4-BROMO-2,2-DIPHENYLBUTYRONITRILE
CAS:
39186-58-8
MF:
C16H14BrN
Structure:
Chemical Name:
2-(3,4-Dimethoxyphenyl)ethanol
CAS:
7417-21-2
MF:
C10H14O3
Structure:
Chemical Name:
2,2-Dimethoxy-2-phenylacetophenone
CAS:
24650-42-8
MF:
C16H16O3
Structure:
Chemical Name:
4-Amino-2,5-dimethylphenol
CAS:
3096-71-7
MF:
C8H11NO
Structure:
Chemical Name:
N,N'-Dimethoxy-N,N'-dimethyloxamide
CAS:
106675-70-1
MF:
C6H12N2O4
Structure:
Chemical Name:
Octabenzone
CAS:
1843-05-6
MF:
C21H26O3
Structure:
Chemical Name:
SUDAN II
CAS:
3118-97-6
MF:
C18H16N2O
Structure:
Chemical Name:
Triphenylene
CAS:
217-59-4
MF:
C18H12
Structure:
Chemical Name:
(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZENE
CAS:
24388-23-6
MF:
C12H17BO2
Structure:
Chemical Name:
Ethanesulfonyl chloride
CAS:
594-44-5
MF:
C2H5ClO2S
Structure:
Chemical Name:
Acetoacetanilide
CAS:
102-01-2
MF:
C10H11NO2
Structure:
Chemical Name:
3,5-DICHLOROSALICYLALDEHYDE
CAS:
90-60-8
MF:
C7H4Cl2O2
Structure:
Chemical Name:
2-BROMOBENZYLAMINE
CAS:
3959-05-5
MF:
C7H8BrN
Structure:
Chemical Name:
3-Hydroxycinnamic acid
CAS:
14755-02-3
MF:
C9H8O3
Structure:
Chemical Name:
2-Chloro-1,3,2-dioxaphospholane-2-oxide
CAS:
6609-64-9
MF:
C2H4ClO3P
Structure:
Chemical Name:
METHYL 2-AMINO-5-BROMOBENZOATE
CAS:
52727-57-8
MF:
C8H8BrNO2
Structure:
Chemical Name:
Borane-pyridine complex
CAS:
110-51-0
MF:
C5H8BN
Structure:
Chemical Name:
(S)-(+)-1,1'-Bi-2-naphthyl ditosylate
CAS:
128544-06-9
MF:
C34H26O6S2
Structure:
Chemical Name:
3-Aminobenzamide
CAS:
3544-24-9
MF:
C7H8N2O
Structure:
Chemical Name:
4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)CHLOROBENZENE
CAS:
195062-61-4
MF:
C12H16BClO2
Structure:
Chemical Name:
Diethyl 2,5-dibromohexanedioate
CAS:
869-10-3
MF:
C10H16Br2O4