Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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Organic reagents

Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.

After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.

8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.

Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.

Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.

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Structure:
Chemical Name:
2-Bromo-6-nitrotoluene
CAS:
55289-35-5
MF:
C7H6BrNO2
Structure:
Chemical Name:
3-Chloro-1-propanol
CAS:
627-30-5
MF:
C3H7ClO
Structure:
Chemical Name:
4-Hydroxybenzyl cyanide
CAS:
14191-95-8
MF:
C8H7NO
Structure:
Chemical Name:
4-(TRIFLUOROMETHOXY)THIOPHENOL
CAS:
169685-29-4
MF:
C7H5F3OS
Structure:
Chemical Name:
Anthranilamide
CAS:
88-68-6
MF:
C7H8N2O
Structure:
Chemical Name:
2-(2-Chloroethoxy)ethanol
CAS:
628-89-7
MF:
C4H9ClO2
Structure:
Chemical Name:
Sodium 2-diazo-1-naphthol-5-sulfonate
CAS:
2657-00-3
MF:
C10H7N2NaO4S
Structure:
Chemical Name:
2-Fluoropyridine-5-boronic acid
CAS:
351019-18-6
MF:
C5H5BFNO2
Structure:
Chemical Name:
3-Tolylboronic acid
CAS:
17933-03-8
MF:
C7H9BO2
Structure:
Chemical Name:
Trimethylsilyl trifluoromethanesulfonate
CAS:
27607-77-8
MF:
C4H9F3O3SSi
Structure:
Chemical Name:
4-Biphenylcarboxylic acid
CAS:
92-92-2
MF:
C13H10O2
Structure:
Chemical Name:
3,4-Dimethoxyphenol
CAS:
2033-89-8
MF:
C8H10O3
Structure:
Chemical Name:
(2-BOC-AMINOPHENYL)BORONIC ACID
CAS:
115377-94-1
MF:
C11H16BNO4
Structure:
Chemical Name:
2-Naphthoic acid
CAS:
93-09-4
MF:
C11H8O2
Structure:
Chemical Name:
1-NAPHTHOL-4-SULFONIC ACID SODIUM SALT
CAS:
6099-57-6
MF:
C10H9NaO4S
Structure:
Chemical Name:
2-Naphthol-6-sulfonic acid potassium salt
CAS:
833-66-9
MF:
C10H9KO4S
Structure:
Chemical Name:
4-METHOXY-2-METHYLPHENYLBORONIC ACID
CAS:
208399-66-0
MF:
C8H11BO3
Structure:
Chemical Name:
m-(Trifluoromethyl)phenylacetic acid
CAS:
351-35-9
MF:
C9H7F3O2
Structure:
Chemical Name:
1-Ethynyl-1-cyclohexanol
CAS:
78-27-3
MF:
C8H12O
Structure:
Chemical Name:
(R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
CAS:
76189-55-4
MF:
C44H32P2
Structure:
Chemical Name:
4-METHOXY-2-(TRIFLUOROMETHYL)BENZOIC ACID
CAS:
127817-85-0
MF:
C9H7F3O3
Structure:
Chemical Name:
3-Glycidoxypropyltrimethoxysilane
CAS:
2530-83-8
MF:
C9H20O5Si
Structure:
Chemical Name:
Adamantane
CAS:
281-23-2
MF:
C10H16
Structure:
Chemical Name:
Cyclopropyl methyl ketone
CAS:
765-43-5
MF:
C5H8O
Structure:
Chemical Name:
4'-Bromoacetophenone
CAS:
99-90-1
MF:
C8H7BrO
Structure:
Chemical Name:
2-Amino-5-iodobenzoic acid
CAS:
5326-47-6
MF:
C7H6INO2
Structure:
Chemical Name:
Diethyl iminodiacetate
CAS:
6290-05-7
MF:
C8H15NO4
Structure:
Chemical Name:
2-Trifluoromethylphenylboronic acid
CAS:
1423-27-4
MF:
C7H6BF3O2
Structure:
Chemical Name:
3,4,5-Trimethoxyphenylacetonitrile
CAS:
13338-63-1
MF:
C11H13NO3
Structure:
Chemical Name:
4-Fluorobenzenesulfonyl chloride
CAS:
349-88-2
MF:
C6H4ClFO2S
Structure:
Chemical Name:
4-Bromobenzyl alcohol
CAS:
873-75-6
MF:
C7H7BrO
Structure:
Chemical Name:
N-(3-BROMOPROPYL)PHTHALIMIDE
CAS:
5460-29-7
MF:
C11H10BrNO2
Structure:
Chemical Name:
Ethyl bromodifluoroacetate
CAS:
667-27-6
MF:
C4H5BrF2O2
Structure:
Chemical Name:
Triethyl borate
CAS:
150-46-9
MF:
C6H15BO3
Structure:
Chemical Name:
o-Anisic acid
CAS:
579-75-9
MF:
C8H8O3
Structure:
Chemical Name:
2-Bromopropionic acid
CAS:
598-72-1
MF:
C3H5BrO2
Structure:
Chemical Name:
1-Bromoadamantane
CAS:
768-90-1
MF:
C10H15Br
Structure:
Chemical Name:
2-Methoxyphenylboronic acid
CAS:
5720-06-9
MF:
C7H9BO3
Structure:
Chemical Name:
4-Iodobenzaldehyde
CAS:
15164-44-0
MF:
C7H5IO
Structure:
Chemical Name:
3-BROMO-5-CHLORO-BENZALDEHYDE
CAS:
188813-05-0
MF:
C7H4BrClO
Structure:
Chemical Name:
Chloroacetaldehyde dimethyl acetal
CAS:
97-97-2
MF:
C4H9ClO2
Structure:
Chemical Name:
3-Methyl-2-butanone
CAS:
563-80-4
MF:
C5H10O
Structure:
Chemical Name:
2-Fluoro-6-iodobenzonitrile
CAS:
79544-29-9
MF:
C7H3FIN
Structure:
Chemical Name:
(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane
CAS:
98737-29-2
MF:
C15H21NO3
Structure:
Chemical Name:
9-Fluorenone
CAS:
486-25-9
MF:
C13H8O
Structure:
Chemical Name:
4-Methoxybenzyl bromide
CAS:
2746-25-0
MF:
C8H9BrO
Structure:
Chemical Name:
2-Methyl-3-nitroanisole
CAS:
4837-88-1
MF:
C8H9NO3
Structure:
Chemical Name:
4-METHOXYCINNAMALDEHYDE
CAS:
1963-36-6
MF:
C10H10O2
Structure:
Chemical Name:
1,1-Cyclobutanedicarboxylic acid
CAS:
5445-51-2
MF:
C6H8O4
Structure:
Chemical Name:
4-Hydroxy-4'-isopropoxydiphenylsulfone
CAS:
95235-30-6
MF:
C15H16O4S
Structure:
Chemical Name:
4-(Bromomethyl)phenylboronic acid
CAS:
68162-47-0
MF:
C7H8BBrO2
Structure:
Chemical Name:
2',4',6'-Trihydroxyacetophenone monohydrate
CAS:
480-66-0
MF:
C8H8O4
Structure:
Chemical Name:
3,5-Dimethoxybenzoic acid
CAS:
1132-21-4
MF:
C9H10O4
Structure:
Chemical Name:
2,4-DICHLOROPHENYLTHIOUREA
CAS:
6326-14-3
MF:
C7H6Cl2N2S
Structure:
Chemical Name:
Hexadecanethiol
CAS:
2917-26-2
MF:
C16H34S
Structure:
Chemical Name:
4-AMINOPHENYLBORONIC ACID HYDROCHLORIDE
CAS:
80460-73-7
MF:
C6H9BClNO2
Structure:
Chemical Name:
2,2-Bis(hydroxymethyl)propionic acid
CAS:
4767-03-7
MF:
C5H10O4
Structure:
Chemical Name:
2-Methylnicotinic acid
CAS:
3222-56-8
MF:
C7H7NO2
Structure:
Chemical Name:
9-FLUORENONE HYDRAZONE
CAS:
13629-22-6
MF:
C13H10N2
Structure:
Chemical Name:
3,3',4,4'-Biphenyltetracarboxylic dianhydride
CAS:
2420-87-3
MF:
C16H6O6
Structure:
Chemical Name:
4-Fluoro-3-(trifluoromethyl)benzaldehyde
CAS:
67515-60-0
MF:
C8H4F4O
Structure:
Chemical Name:
4-Hydroxy-3-nitrobenzoic acid
CAS:
616-82-0
MF:
C7H5NO5
Structure:
Chemical Name:
3,4-Dichlorophenol
CAS:
95-77-2
MF:
C6H4Cl2O
Structure:
Chemical Name:
4-tert-Butylphenol
CAS:
98-54-4
MF:
C10H14O
Structure:
Chemical Name:
4-Cyanobenzaldehyde
CAS:
105-07-7
MF:
C8H5NO
Structure:
Chemical Name:
2-(Trifluoromethyl)phenylthiourea
CAS:
1736-71-6
MF:
C8H7F3N2S
Structure:
Chemical Name:
2,3-Dimethylphenylboronic acid
CAS:
183158-34-1
MF:
C8H11BO2
Structure:
Chemical Name:
Methyl 2,4-dihydroxybenzoate
CAS:
2150-47-2
MF:
C8H8O4
Structure:
Chemical Name:
N-METHYLOCTYLAMINE
CAS:
2439-54-5
MF:
C9H21N
Structure:
Chemical Name:
Benzyl chloromethyl ether
CAS:
3587-60-8
MF:
C8H9ClO
Structure:
Chemical Name:
1-Boc-3-(Amino)azetidine
CAS:
193269-78-2
MF:
C8H16N2O2
Structure:
Chemical Name:
2'-FLUORO-5'-(TRIFLUOROMETHYL)ACETOPHENONE
CAS:
202664-53-7
MF:
C9H6F4O
Structure:
Chemical Name:
1-Adamantanol
CAS:
768-95-6
MF:
C10H16O
Structure:
Chemical Name:
2,4-Dichlorophenylacetic acid
CAS:
19719-28-9
MF:
C8H6Cl2O2
Structure:
Chemical Name:
Methyl 4-bromobenzoate
CAS:
619-42-1
MF:
C8H7BrO2
Structure:
Chemical Name:
Cyclobutyl bromide
CAS:
4399-47-7
MF:
C4H7Br
Structure:
Chemical Name:
1,4-Benzoquinone dioxime
CAS:
105-11-3
MF:
C6H6N2O2
Structure:
Chemical Name:
Malonyl chloride
CAS:
1663-67-8
MF:
C3H2Cl2O2
Structure:
Chemical Name:
5-Chloro-1-indanone
CAS:
42348-86-7
MF:
C9H7ClO
Structure:
Chemical Name:
1,4-BENZENEDITHIOL
CAS:
624-39-5
MF:
C6H6S2
Structure:
Chemical Name:
2-Ethoxybenzaldehyde
CAS:
613-69-4
MF:
C9H10O2
Structure:
Chemical Name:
3-Trifluoromethoxyphenylboronic acid
CAS:
179113-90-7
MF:
C7H6BF3O3
Structure:
Chemical Name:
Monobenzone
CAS:
103-16-2
MF:
C13H12O2
Structure:
Chemical Name:
Chloromethyl chlorosulfate
CAS:
49715-04-0
MF:
CH2Cl2O3S
Structure:
Chemical Name:
Methyl 4-trifluoromethylbenzoate
CAS:
2967-66-0
MF:
C9H7F3O2
Structure:
Chemical Name:
(R)-Glycidyl butyrate
CAS:
60456-26-0
MF:
C7H12O3
Structure:
Chemical Name:
2,5-Dimethylphenol
CAS:
95-87-4
MF:
C8H10O
Structure:
Chemical Name:
3-Bromo-1-propanol
CAS:
627-18-9
MF:
C3H7BrO
Structure:
Chemical Name:
2-BROMO-2',5'-DIMETHOXYACETOPHENONE
CAS:
1204-21-3
MF:
C10H11BrO3
Structure:
Chemical Name:
alpha,alpha,alpha-Trifluoro-o-cresol
CAS:
444-30-4
MF:
C7H5F3O
Structure:
Chemical Name:
6-Methoxy-1H-indanone
CAS:
13623-25-1
MF:
C10H10O2
Structure:
Chemical Name:
Pivaldehyde
CAS:
630-19-3
MF:
C5H10O
Structure:
Chemical Name:
3,5-Dichlorobenzaldehyde
CAS:
10203-08-4
MF:
C7H4Cl2O
Structure:
Chemical Name:
Cyclopropylacetylene
CAS:
6746-94-7
MF:
C5H6
Structure:
Chemical Name:
4-tert-Butylbenzoic acid
CAS:
98-73-7
MF:
C11H14O2
Structure:
Chemical Name:
2,3,5-Trimethylphenol
CAS:
697-82-5
MF:
C9H12O
Structure:
Chemical Name:
Dimethyl fluoromalonate
CAS:
344-14-9
MF:
C5H7FO4
Structure:
Chemical Name:
2-Hydroxymethylphenylboronic acid
CAS:
87199-14-2
MF:
C7H9BO3
Structure:
Chemical Name:
Methyl 3-aminocrotonate
CAS:
14205-39-1
MF:
C5H9NO2
Structure:
Chemical Name:
4-Bromoanisole
CAS:
104-92-7
MF:
C7H7BrO