Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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Organic reagents

Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.

After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.

8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.

Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.

Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.

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Structure:
Chemical Name:
3-Chloro-4-methylphenylboronic acid
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175883-63-3
MF:
C7H8BClO2
Structure:
Chemical Name:
2-Chloromandelic acid
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10421-85-9
MF:
C8H7ClO3
Structure:
Chemical Name:
1-(2-NITROPHENYL)-2-THIOUREA
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51039-84-0
MF:
C7H7N3O2S
Structure:
Chemical Name:
2-Cyanophenylboronic acid
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138642-62-3
MF:
C7H6BNO2
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Chemical Name:
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C6H10O3
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Chemical Name:
[2.2]Paracyclophane
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1633-22-3
MF:
C16H16
Structure:
Chemical Name:
2,2-Dimethylsuccinic acid
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597-43-3
MF:
C6H10O4
Structure:
Chemical Name:
5-Acetyl-2-thiopheneboronic acid
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206551-43-1
MF:
C6H7BO3S
Structure:
Chemical Name:
3-Bromo-2-methylbenzoic acid
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76006-33-2
MF:
C8H7BrO2
Structure:
Chemical Name:
4-Bromo-2-chlorobenzoic acid
CAS:
59748-90-2
MF:
C7H4BrClO2
Structure:
Chemical Name:
2,4-Dihydroxyacetophenone
CAS:
89-84-9
MF:
C8H8O3
Structure:
Chemical Name:
Bis(trimethylsilyl)acetylene
CAS:
14630-40-1
MF:
C8H18Si2
Structure:
Chemical Name:
3,4-METHYLENEDIOXYPHENYLBORONIC ACID
CAS:
94839-07-3
MF:
C7H7BO4
Structure:
Chemical Name:
Trisodium naphthalene-1,3,6-trisulphonate
CAS:
5182-30-9
MF:
C10H5Na3O9S3
Structure:
Chemical Name:
1,5,7-Triazabicyclo[4.4.0]dec-5-ene
CAS:
5807-14-7
MF:
C7H13N3
Structure:
Chemical Name:
5-Hydroxyisophthalic acid
CAS:
618-83-7
MF:
C8H6O5
Structure:
Chemical Name:
2-Hydroxyphenylboronic acid
CAS:
89466-08-0
MF:
C6H7BO3
Structure:
Chemical Name:
2-Hydroxyphenylacetic acid
CAS:
614-75-5
MF:
C8H8O3
Structure:
Chemical Name:
4-Bromophenyl methyl sulfone
CAS:
3466-32-8
MF:
C7H7BrO2S
Structure:
Chemical Name:
1-(4-ACETYLPHENYL)-2-THIOUREA
CAS:
71680-92-7
MF:
C9H10N2OS
Structure:
Chemical Name:
4-Trifluoromethoxyphenylboronic acid
CAS:
139301-27-2
MF:
C7H6BF3O3
Structure:
Chemical Name:
3-CYANOBENZYL ALCOHOL
CAS:
874-97-5
MF:
C8H7NO
Structure:
Chemical Name:
3-Ethoxycarbonylphenylboronic acid
CAS:
4334-87-6
MF:
C9H11BO4
Structure:
Chemical Name:
5-Chlorothiophene-2-sulfonyl chloride
CAS:
2766-74-7
MF:
C4H2Cl2O2S2
Structure:
Chemical Name:
N,N'-Diisopropylcarbodiimide
CAS:
693-13-0
MF:
C7H14N2
Structure:
Chemical Name:
2-Amino-5-nitrobenzoic acid
CAS:
616-79-5
MF:
C7H6N2O4
Structure:
Chemical Name:
Bis(pinacolato)diboron
CAS:
73183-34-3
MF:
C12H24B2O4
Structure:
Chemical Name:
Ethyl 2-chloronicotinate
CAS:
1452-94-4
MF:
C8H8ClNO2
Structure:
Chemical Name:
N,O-BIS(TRIFLUOROACETYL)HYDROXYLAMINE
CAS:
684-78-6
MF:
C4HF6NO3
Structure:
Chemical Name:
Benzyltriethylammonium bromide
CAS:
5197-95-5
MF:
C13H22BrN
Structure:
Chemical Name:
4-Fluorophenethyl alcohol
CAS:
7589-27-7
MF:
C8H9FO
Structure:
Chemical Name:
4,4'-Methylenebis(N,N-dimethylaniline)
CAS:
101-61-1
MF:
C17H22N2
Structure:
Chemical Name:
1-OXO-2,3-DIHYDRO-1H-INDENE-5-CARBONITRILE
CAS:
25724-79-2
MF:
C10H7NO
Structure:
Chemical Name:
4-Methylsulphonylbenzoic acid
CAS:
4052-30-6
MF:
C8H8O4S
Structure:
Chemical Name:
3-Hydroxyphenylacetic acid
CAS:
621-37-4
MF:
C8H8O3
Structure:
Chemical Name:
Sodium xylenesulfonate
CAS:
1300-72-7
MF:
C8H9NaO3S
Structure:
Chemical Name:
2-Fluoro-5-methylbenzaldehyde
CAS:
93249-44-6
MF:
C8H7FO
Structure:
Chemical Name:
Coumarin 120
CAS:
26093-31-2
MF:
C10H9NO2
Structure:
Chemical Name:
Tetrapropylammonium bromide
CAS:
1941-30-6
MF:
C12H28BrN
Structure:
Chemical Name:
CHES
CAS:
103-47-9
MF:
C8H17NO3S
Structure:
Chemical Name:
(4-CHLORO-BENZYL)-METHYL-AMINE
CAS:
104-11-0
MF:
C8H10ClN
Structure:
Chemical Name:
2,4-Dimethoxybenzoic acid
CAS:
91-52-1
MF:
C9H10O4
Structure:
Chemical Name:
4-Iodobenzoic acid
CAS:
619-58-9
MF:
C7H5IO2
Structure:
Chemical Name:
Ammonium 2-hydroxyethanesulphonate
CAS:
57267-78-4
MF:
C2H9NO4S
Structure:
Chemical Name:
3-BENZOYLPROPIONIC ACID
CAS:
2051-95-8
MF:
C10H10O3
Structure:
Chemical Name:
1,4-dibromonaphthalene
CAS:
83-53-4
MF:
C10H6Br2
Structure:
Chemical Name:
Methyl cyclopropane carboxylate
CAS:
2868-37-3
MF:
C5H8O2
Structure:
Chemical Name:
Bromoacetaldehyde diethyl acetal
CAS:
2032-35-1
MF:
C6H13BrO2
Structure:
Chemical Name:
5-METHYLTHIO-1,3,4-THIADIAZOLE-2-THIOL
CAS:
6264-40-0
MF:
C3H4N2S3
Structure:
Chemical Name:
18-Crown-6
CAS:
17455-13-9
MF:
C12H24O6
Structure:
Chemical Name:
2-Bromo-2',4'-dichloroacetophenone
CAS:
2631-72-3
MF:
C8H5BrCl2O
Structure:
Chemical Name:
2,4-Dichlorophenol
CAS:
120-83-2
MF:
C6H4Cl2O
Structure:
Chemical Name:
1-(4-HYDROXYPHENYL)-2-THIOUREA
CAS:
1520-27-0
MF:
C7H8N2OS
Structure:
Chemical Name:
2,4-Dihydroxybenzoic acid
CAS:
89-86-1
MF:
C7H6O4
Structure:
Chemical Name:
1-Boc-3-(Aminomethyl)azetidine
CAS:
325775-44-8
MF:
C9H18N2O2
Structure:
Chemical Name:
4-Methylphenylacetic acid
CAS:
622-47-9
MF:
C9H10O2
Structure:
Chemical Name:
4-FLUORO-2-(TRIFLUOROMETHYL)BENZENEBORONIC ACID
CAS:
182344-16-7
MF:
C7H5BF4O2
Structure:
Chemical Name:
3-Bromophenylboronic acid
CAS:
89598-96-9
MF:
C6H6BBrO2
Structure:
Chemical Name:
5-Fluoro-2-methylphenylboronic acid
CAS:
163517-62-2
MF:
C7H8BFO2
Structure:
Chemical Name:
2-Chloro-5-trifluoromethylbenzaldehyde
CAS:
82386-89-8
MF:
C8H4ClF3O
Structure:
Chemical Name:
3,5-Dichlorobenzoic acid
CAS:
51-36-5
MF:
C7H4Cl2O2
Structure:
Chemical Name:
tert-Butyldimethylsilyl chloride
CAS:
18162-48-6
MF:
C6H15ClSi
Structure:
Chemical Name:
3-Methylanthranilic acid
CAS:
4389-45-1
MF:
C8H9NO2
Structure:
Chemical Name:
3,4,5-Trimethoxybenzaldehyde
CAS:
86-81-7
MF:
C10H12O4
Structure:
Chemical Name:
Dimethyl malonate
CAS:
108-59-8
MF:
C5H8O4
Structure:
Chemical Name:
2-Bromo-3-nitrobenzoic acid
CAS:
573-54-6
MF:
C7H4BrNO4
Structure:
Chemical Name:
2,6-Dichlorobenzyl acetonitrile
CAS:
3215-64-3
MF:
C8H5Cl2N
Structure:
Chemical Name:
Tributyl borate
CAS:
688-74-4
MF:
C12H27BO3
Structure:
Chemical Name:
m-Toluic acid
CAS:
99-04-7
MF:
C8H8O2
Structure:
Chemical Name:
(3,4-Dimethoxyphenyl)acetic acid
CAS:
93-40-3
MF:
C10H12O4
Structure:
Chemical Name:
3-PYRIDINECARBOXAMIDINE
CAS:
23255-20-1
MF:
C6H7N3
Structure:
Chemical Name:
4-IODO-3-METHYLBENZOIC ACID
CAS:
52107-87-6
MF:
C8H7IO2
Structure:
Chemical Name:
2,4-Dichlorobenzyl alcohol
CAS:
1777-82-8
MF:
C7H6Cl2O
Structure:
Chemical Name:
3,4-Dichlorophenylboronic acid
CAS:
151169-75-4
MF:
C6H5BCl2O2
Structure:
Chemical Name:
1,6-Hexanediol
CAS:
629-11-8
MF:
C6H14O2
Structure:
Chemical Name:
2-Fluorobenzenesulfonyl chloride
CAS:
2905-21-7
MF:
C6H4ClFO2S
Structure:
Chemical Name:
Cyclohexanecarboxylic acid chloride
CAS:
2719-27-9
MF:
C7H11ClO
Structure:
Chemical Name:
Sodium 1-octanesulfonate
CAS:
5324-84-5
MF:
C8H17NaO3S
Structure:
Chemical Name:
Ethyl glyoxalate
CAS:
924-44-7
MF:
C4H6O3
Structure:
Chemical Name:
3-Chloroanisole
CAS:
2845-89-8
MF:
C7H7ClO
Structure:
Chemical Name:
3-Aminoacetophenone
CAS:
99-03-6
MF:
C8H9NO
Structure:
Chemical Name:
11-Bromo-1-undecanol
CAS:
1611-56-9
MF:
C11H23BrO
Structure:
Chemical Name:
m-Phthalaldehyde
CAS:
626-19-7
MF:
C8H6O2
Structure:
Chemical Name:
(4-FLUORO-BENZYL)-METHYL-AMINE
CAS:
405-66-3
MF:
C8H10FN
Structure:
Chemical Name:
m-Anisidine
CAS:
536-90-3
MF:
C7H9NO
Structure:
Chemical Name:
3-Hydroxyphenylboronic acid
CAS:
87199-18-6
MF:
C6H7BO3
Structure:
Chemical Name:
3-Methoxyphenylboronic acid
CAS:
10365-98-7
MF:
C7H9BO3
Structure:
Chemical Name:
(4-BOC-AMINOPHENYL)BORONIC ACID
CAS:
380430-49-9
MF:
C11H16BNO4
Structure:
Chemical Name:
4,4-Difluorocyclohexanecarboxylic acid
CAS:
122665-97-8
MF:
C7H10F2O2
Structure:
Chemical Name:
POLYANETHOLESULFONIC ACID SODIUM SALT
CAS:
52993-95-0
MF:
C6H12Na2O6S4
Structure:
Chemical Name:
1,4,7-Triazacyclononane
CAS:
4730-54-5
MF:
C6H15N3
Structure:
Chemical Name:
2,4'-Dibromoacetophenone
CAS:
99-73-0
MF:
C8H6Br2O
Structure:
Chemical Name:
N-Hydroxyethylphthalimide
CAS:
3891-07-4
MF:
C10H9NO3
Structure:
Chemical Name:
2-Bromo-6-methoxynaphthalene
CAS:
5111-65-9
MF:
C11H9BrO
Structure:
Chemical Name:
4-Nitrobenzoic acid
CAS:
62-23-7
MF:
C7H5NO4
Structure:
Chemical Name:
3,5-Dibromobenzaldehyde
CAS:
56990-02-4
MF:
C7H4Br2O
Structure:
Chemical Name:
3-Chloroperoxybenzoic acid
CAS:
937-14-4
MF:
C7H5ClO3
Structure:
Chemical Name:
3,5-Di-tert-butylsalicylaldehyde
CAS:
37942-07-7
MF:
C15H22O2
Structure:
Chemical Name:
1-Bromo-4-ethoxy-2,3-difluorobenzene
CAS:
156573-09-0
MF:
C8H7BrF2O
Structure:
Chemical Name:
4-Pyridineboronic acid pinacol ester
CAS:
181219-01-2
MF:
C11H16BNO2