Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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Organic reagents

Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.

After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.

8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.

Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.

Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.

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Structure:
Chemical Name:
2,4,5-TRICHLOROBENZENESULFONYL CHLORIDE
CAS:
15945-07-0
MF:
C6H2Cl4O2S
Structure:
Chemical Name:
Thianthrene
CAS:
92-85-3
MF:
C12H8S2
Structure:
Chemical Name:
2,3,5,6-TETRAFLUOROANISOLE
CAS:
2324-98-3
MF:
C7H4F4O
Structure:
Chemical Name:
FLAVONOL-2'-SULFONIC ACID SODIUM SALT
CAS:
77125-87-2
MF:
C15H9NaO6S
Structure:
Chemical Name:
Di(ethylene glycol) vinyl ether
CAS:
929-37-3
MF:
C6H12O3
Structure:
Chemical Name:
4-Propylbenzoic acid
CAS:
2438-05-3
MF:
C10H12O2
Structure:
Chemical Name:
PHENYLSELENOL
CAS:
645-96-5
MF:
C6H6Se
Structure:
Chemical Name:
N,N'-Diethylthiourea
CAS:
105-55-5
MF:
C5H12N2S
Structure:
Chemical Name:
Phenethyl caffeate
CAS:
104594-70-9
MF:
C17H16O4
Structure:
Chemical Name:
8-ETHOXYQUINOLINE-5-SULFONIC ACID SODIUM SALT HEMIHYDRATE
CAS:
80789-76-0
MF:
C11H14NNaO5S
Structure:
Chemical Name:
1,4-Diiodobutane
CAS:
628-21-7
MF:
C4H8I2
Structure:
Chemical Name:
4-Chlorobenzenesulfonic acid
CAS:
98-66-8
MF:
C6H5ClO3S
Structure:
Chemical Name:
BENZALDEHYDE N,N-DIMETHYLHYDRAZONE
CAS:
1075-70-3
MF:
C9H12N2
Structure:
Chemical Name:
2,3,4,5,6-PENTAFLUOROSTYRENE
CAS:
653-34-9
MF:
C8H3F5
Structure:
Chemical Name:
Bromoacetyl chloride
CAS:
22118-09-8
MF:
C2H2BrClO
Structure:
Chemical Name:
2-ANTHRACENEBORONIC ACID
CAS:
141981-64-8
MF:
C14H11BO2
Structure:
Chemical Name:
DL-GAMMA-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE
CAS:
924-49-2
MF:
C4H9NO3
Structure:
Chemical Name:
2-FLUOROPHENYL ISOTHIOCYANATE
CAS:
38985-64-7
MF:
C7H4FNS
Structure:
Chemical Name:
HEXADECANEDIOIC ACID
CAS:
505-54-4
MF:
C16H30O4
Structure:
Chemical Name:
TRANS-ACONITIC ACID
CAS:
4023-65-8
MF:
C6H6O6
Structure:
Chemical Name:
4-(4-NITROPHENYLAZO)-1-NAPHTHOL
CAS:
5290-62-0
MF:
C16H11N3O3
Structure:
Chemical Name:
Difurazone
CAS:
804-36-4
MF:
C14H12N6O6
Structure:
Chemical Name:
2-Isocyanatoethyl methacrylate
CAS:
30674-80-7
MF:
C7H9NO3
Structure:
Chemical Name:
Tioxolone
CAS:
4991-65-5
MF:
C7H4O3S
Structure:
Chemical Name:
4-ETHYLTHIOPHENOL
CAS:
4946-13-8
MF:
C8H10S
Structure:
Chemical Name:
Rhodamine 123
CAS:
62669-70-9
MF:
C21H17ClN2O3
Structure:
Chemical Name:
1,2-(Methylenedioxy)-4-nitrobenzene
CAS:
2620-44-2
MF:
C7H5NO4
Structure:
Chemical Name:
1,8-DIIODOOCTANE
CAS:
24772-63-2
MF:
C8H16I2
Structure:
Chemical Name:
1-(4-Methylphenyl)ethanol
CAS:
536-50-5
MF:
C9H12O
Structure:
Chemical Name:
Hydroquinone bis(2-hydroxyethyl)ether
CAS:
104-38-1
MF:
C10H14O4
Structure:
Chemical Name:
1,3-DIETHYNYLBENZENE
CAS:
1785-61-1
MF:
C10H6
Structure:
Chemical Name:
Didodecyl sulfide
CAS:
2469-45-6
MF:
C24H50S
Structure:
Chemical Name:
Methyl nitroacetate
CAS:
2483-57-0
MF:
C3H5NO4
Structure:
Chemical Name:
Benzylmalonic acid
CAS:
616-75-1
MF:
C10H10O4
Structure:
Chemical Name:
1,5-DICHLOROANTHRAQUINONE
CAS:
82-46-2
MF:
C14H6Cl2O2
Structure:
Chemical Name:
Butyl glycidyl ether
CAS:
2426-08-6
MF:
C7H14O2
Structure:
Chemical Name:
4-Hydroxyphthalic acid
CAS:
610-35-5
MF:
C8H6O5
Structure:
Chemical Name:
4-(N-OCTYLOXY)BENZENEBORONIC ACID
CAS:
121554-09-4
MF:
C14H23BO3
Structure:
Chemical Name:
Butoxybenzene
CAS:
1126-79-0
MF:
C10H14O
Structure:
Chemical Name:
4-ACETOXYBENZALDEHYDE
CAS:
878-00-2
MF:
C9H8O3
Structure:
Chemical Name:
3-METHOXYCATECHOL
CAS:
934-00-9
MF:
C7H8O3
Structure:
Chemical Name:
3-CHLOROPHENETHYLALCOHOL
CAS:
5182-44-5
MF:
C8H9ClO
Structure:
Chemical Name:
N,N'-DIHEXYLTHIOUREA
CAS:
21071-28-3
MF:
C13H28N2S
Structure:
Chemical Name:
3,4-DIFLUOROBENZAMIDE
CAS:
85118-04-3
MF:
C7H5F2NO
Structure:
Chemical Name:
3-FORMYL BENZAMIDINE HYDROCHLORIDE
CAS:
57081-01-3
MF:
C8H9ClN2O
Structure:
Chemical Name:
Methyl naphthalene-1-acetate
CAS:
2876-78-0
MF:
C13H12O2
Structure:
Chemical Name:
2,6-DICHLOROPHENETHYLAMINE
CAS:
14573-23-0
MF:
C8H9Cl2N
Structure:
Chemical Name:
10,12-PENTACOSADIYNOIC ACID
CAS:
66990-32-7
MF:
C25H42O2
Structure:
Chemical Name:
2-(Methacryloyloxy)ethyl acetoacetate
CAS:
21282-97-3
MF:
C10H14O5
Structure:
Chemical Name:
9-ETHYL-3-(N-BUTYL-N-PHENYLHYDRAZONOMETHYL)CARBAZOLE
CAS:
88107-84-0
MF:
C25H27N3
Structure:
Chemical Name:
4-NITROBENZENESULFONYL FLUORIDE
CAS:
349-96-2
MF:
C6H4FNO4S
Structure:
Chemical Name:
2-Methylphenyl isothiocyanate
CAS:
614-69-7
MF:
C8H7NS
Structure:
Chemical Name:
Cyclopentane-1,1-diacetic acid
CAS:
16713-66-9
MF:
C9H14O4
Structure:
Chemical Name:
2-Amino-6-bromophenol
CAS:
28165-50-6
MF:
C6H6BrNO
Structure:
Chemical Name:
4-Bromo-benzenesulfonic acid potassium salt
CAS:
66788-58-7
MF:
C6H4BrKO3S
Structure:
Chemical Name:
2-FLUOROPHENYLMETHYLSULFONE
CAS:
654-47-7
MF:
C7H7FO2S
Structure:
Chemical Name:
2-ETHOXY-MALONIC ACID DIETHYL ESTER
CAS:
37555-99-0
MF:
C9H16O5
Structure:
Chemical Name:
1-Phenylcyclobutanecarbonitrile
CAS:
14377-68-5
MF:
C11H11N
Structure:
Chemical Name:
2,3-Dibromopropionyl chloride
CAS:
18791-02-1
MF:
C3H3Br2ClO
Structure:
Chemical Name:
2-TRIMETHYLSILYL-1,3-DITHIANE
CAS:
13411-42-2
MF:
C7H16S2Si
Structure:
Chemical Name:
2',5'-DIMETHYLACETOPHENONE
CAS:
2142-73-6
MF:
C10H12O
Structure:
Chemical Name:
BENZYL PHENYL SULFIDE
CAS:
831-91-4
MF:
C13H12S
Structure:
Chemical Name:
BENZANILIDE
CAS:
93-98-1
MF:
C13H11NO
Structure:
Chemical Name:
beta-Methylphenethyl alcohol
CAS:
1123-85-9
MF:
C9H12O
Structure:
Chemical Name:
3-PHENYLPHENOL
CAS:
580-51-8
MF:
C12H10O
Structure:
Chemical Name:
METHYL DIFLUOROACETATE
CAS:
433-53-4
MF:
C3H4F2O2
Structure:
Chemical Name:
2-Methylene-1,3-propanediol
CAS:
3513-81-3
MF:
C4H8O2
Structure:
Chemical Name:
1-INDANOL
CAS:
6351-10-6
MF:
C9H10O
Structure:
Chemical Name:
3-ETHOXY-2-CYCLOHEXEN-1-ONE
CAS:
5323-87-5
MF:
C8H12O2
Structure:
Chemical Name:
1-CYCLOPROPYLETHANOL
CAS:
765-42-4
MF:
C5H10O
Structure:
Chemical Name:
9-ETHYL-3-[N-ETHYL-N-(M-TOLYL)HYDRAZONOMETHYL]CARBAZOLE
CAS:
81380-24-7
MF:
C24H25N3
Structure:
Chemical Name:
Ethyl 3-bromo-2-(bromomethyl)propionate
CAS:
58539-11-0
MF:
C6H10Br2O2
Structure:
Chemical Name:
2-(DIPHENYLPHOSPHINO)ETHYLTRIETHOXYSILANE
CAS:
18586-39-5
MF:
C20H29O3PSi
Structure:
Chemical Name:
3,6-DIFLUOROPHTHALIC ANHYDRIDE
CAS:
652-40-4
MF:
C8H2F2O3
Structure:
Chemical Name:
Diethyl bis(hydroxymethyl)malonate
CAS:
20605-01-0
MF:
C9H16O6
Structure:
Chemical Name:
4-BROMO-3-NITROANILINE
CAS:
53324-38-2
MF:
C6H5BrN2O2
Structure:
Chemical Name:
TRIISOPROPYLSILANETHIOL
CAS:
156275-96-6
MF:
C9H22SSi
Structure:
Chemical Name:
2-CHLOROPHENYL ISOTHIOCYANATE
CAS:
2740-81-0
MF:
C7H4ClNS
Structure:
Chemical Name:
MOPSO sodium salt
CAS:
79803-73-9
MF:
C7H16NNaO5S
Structure:
Chemical Name:
2-Ethylhexyl methacrylate
CAS:
688-84-6
MF:
C12H22O2
Structure:
Chemical Name:
Dimethylphenylsilane
CAS:
766-77-8
MF:
C8H12Si
Structure:
Chemical Name:
2-Nitrodiphenyl
CAS:
86-00-0
MF:
C12H9NO2
Structure:
Chemical Name:
1-tert-Butyl-3-phenylthiourea
CAS:
14327-04-9
MF:
C11H16N2S
Structure:
Chemical Name:
Disodium 3,3'-(2-butyne-1,4-diylbis(oxy))bis(2-hydroxypropanesulphonate)
CAS:
67874-62-8
MF:
C10H16Na2O10S2
Structure:
Chemical Name:
1-(4-chlorophenyl)-3-cyanoguanidine
CAS:
1482-62-8
MF:
C8H7ClN4
Structure:
Chemical Name:
N-HYDROXY-2-METHYL-BENZAMIDINE
CAS:
40312-14-9
MF:
C8H10N2O
Structure:
Chemical Name:
ALLYL PHENYL SULFIDE
CAS:
5296-64-0
MF:
C9H10S
Structure:
Chemical Name:
Ethyl 4-bromocrotonate
CAS:
37746-78-4
MF:
C6H9BrO2
Structure:
Chemical Name:
4-(ETHYLSULFONYL)PHENYLBORONIC ACID
CAS:
352530-24-6
MF:
C8H11BO4S
Structure:
Chemical Name:
4-Formylphenoxyacetic acid
CAS:
22042-71-3
MF:
C9H8O4
Structure:
Chemical Name:
PYRIDINE-2-CARBOXALDEHYDE 4-NITROPHENYLHYDRAZONE
CAS:
70421-66-8
MF:
C12H10N4O2
Structure:
Chemical Name:
Ethyl trimethylacetate
CAS:
3938-95-2
MF:
C7H14O2
Structure:
Chemical Name:
Sodium 2-sulfoethyl methacrylate
CAS:
1804-87-1
MF:
C6H9NaO5S
Structure:
Chemical Name:
2,2,4-TRIMETHYL-1,3-PENTANEDIOL DIISOBUTYRATE
CAS:
6846-50-0
MF:
C16H30O4
Structure:
Chemical Name:
Vinyl chloroacetate
CAS:
2549-51-1
MF:
C4H5ClO2
Structure:
Chemical Name:
N-methylisatoic anhydride
CAS:
10328-92-4
MF:
C9H7NO3
Structure:
Chemical Name:
2,6-Diisopropylphenyl isocyanate
CAS:
28178-42-9
MF:
C13H17NO
Structure:
Chemical Name:
1-BUTYL-1-METHYLPYRROLIDINIUM BIS(TRIFLUOROMETHYLSULFONYL)IMIDE
CAS:
223437-11-4
MF:
C11H20F6N2O4S2
Structure:
Chemical Name:
1,3-Benzenedimethanol
CAS:
626-18-6
MF:
C8H10O2
Structure:
Chemical Name:
3,4,5-Trimethoxybenzylamine
CAS:
18638-99-8
MF:
C10H15NO3