Ginsenoside Rh1
Ginsenoside Rh1 Basic information
- Product Name:
- Ginsenoside Rh1
- Synonyms:
-
- sanchinoside rh1
- (3beta,6alpha,12beta)-3,12,20-trihydroxydammar-24-en-6-yl?beta-d-glucopyranoside
- Ginsenoside Rh1 (Prosapogenin A2
- GINSENOSIDE RH1
- (20S)-6α-(β-D-Glucopyranosyloxy)-3β,12β,20-trihydroxydammara-24-ene
- (20S)-6α-(β-D-Glucopyranosyloxy)dammar-24-ene-3β,12β,20-triol
- 3β,12β,20-Trihydroxy-5α-dammar-24-en-6α-yl β-D-glucopyranoside
- 6α-(β-D-Glucopyranosyloxy)-dammara-24-ene-3β,12β,20-triol
- CAS:
- 63223-86-9
- MF:
- C36H62O9
- MW:
- 638.88
- Product Categories:
-
- Inhibitors
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Ginsenoside series
- Mol File:
- 63223-86-9.mol
Ginsenoside Rh1 Chemical Properties
- Boiling point:
- 755.1±60.0 °C(Predicted)
- Density
- 1.23
- storage temp.
- 2-8°C
- solubility
- DMSO : 100 mg/mL (156.53 mM; Need ultrasonic)
- form
- powder
- pka
- 12.91±0.70(Predicted)
- color
- White
- LogP
- 3.740 (est)
Ginsenoside Rh1 Usage And Synthesis
Uses
20(S)?-?Ginsenoside Rh1 is an anti-cancer agent found in the leaves of ginseng.
Definition
ChEBI: (20S)-ginsenoside Rh1 is a tetracyclic triterpenoid that is (20S)-protopanaxadiol which is substituted by beta-D-glucoside at the 6alpha position. It has a role as a plant metabolite. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a tetracyclic triterpenoid, a ginsenoside, a 3beta-hydroxy steroid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.
in vivo
When high-fat diet (HFD) fed mice for 8 weeks, body and epididymal fat weight gains are significantly increased compared to those of low-fat diet (LFD)-fed mice. However, when Ginsenoside Rh1 is treated in HFD-fed mice, body and epididymal fat weight gains are significantly decrease compared with those of the HFD-fed mice. TG, glucose, insulin, total cholesterol, and HDL levels in the blood are significantly increased in HFD-fed mice group compared to LFD-fed mice group. Treatment with Ginsenoside Rh1 in HFD-fed mice significantly lowers TG level alone[1].
IC 50
PPAR-γ; IL-6; IL-1β
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Ginsenoside Rh1(63223-86-9)Related Product Information
- R-form-Ginsenoside Rh2,GINSENOSIDE RH2
- ginsenoside Rh3
- Ginsenoside Rb3
- Ginsenoside-Rg5
- ginsenoside Rh(4)
- Ginsenoside Rg1
- Ginsenoside Rf
- Ginsenoside Rg2
- Ginsenoside Rd
- Ginsenoside Rk3
- GINSENOSIDE RB2
- GinsenosideRo
- GINSENOSIDEF1
- Ginsenoside Re
- Ginsenoside Rb1
- Ginsenoside CK
- Ginsenoside Rg6
- Ginsenoside Rc