Acid-PEG5-t-butyl ester Chemical Properties

Boiling point:

495.2±45.0 °C(Predicted)

Density 

1.109±0.06 g/cm3(Predicted)

solubility 

Soluble in Water, DMSO, DCM, DMF

pka

4.28±0.10(Predicted)

Acid-PEG5-t-butyl ester Usage And Synthesis

Description

Acid-PEG5-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Acid-PEG5-t-butyl ester(1309460-29-4)Related Product Information

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