Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II) Chemical Properties

Melting point:

158-160°C

form 

Powder

color 

yellow

InChI

InChI=1S/C12H9N.C12H27P.ClH.Pd/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-10(2,3)13(11(4,5)6)12(7,8)9;;/h1-6,8-9,13H;1-9H3;1H;/q-2;;;+2

InChIKey

CCFGXRYKSYUWKT-UHFFFAOYSA-N

SMILES

P([Pd+2]1(NC2=CC=CC=C2C2=CC=CC=[C-]12)[Cl-])(C(C)(C)C)(C(C)(C)C)C(C)(C)C

Safety Information

WGK Germany 

3

HS Code 

2931.90.6000

Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II) Usage And Synthesis

Physical Form

Light yellow to Amber to Dark green powder to crystal.

Reaction

Catalyst for the Suzuki Coupling of brominated 2,1-borazaronaphthalenes and potassium organotrifluoroborates.

Uses

P(t-Bu)₃ Pd G2 (Chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)] palladium(II), Pd/P(t-Bu)₃) may be used as catalyst in the following studies:

• Synthesis of sterically hindered biaryls (tetra-ortho-substituted), via cross-coupling reactions of aryl chlorides.
• Stille cross-couplings reactions of aryl chloride.
• Synthesis of chloropeptin I, via Stille cross-coupling reaction.
• Heck reaction.
• Negishi cross-coupling reactions.

Application

Catalyst for the Suzuki Coupling of brominated 2,1-borazaronaphthalenes and potassium organotrifluoroborates.

General Description

P(t-Bu)₃ Pd G2 (Chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)] palladium(II)) is a second generation (G2) precatalyst containing a biphenyl-based ligand. Product participates in various palladium catalyzed cross-coupling reactions, C-C, C-N and C-O bond formation reactions, and Suzuki-Miyaura coupling reactions. It generates active Pd catalyst at room temperature in the presence of weak phosphate or carbonate bases. It has been proposed as an active catalyst for use in Stille reactions of aryl halides (bromides and chlorides).

Chloro[(tri-tert-butylphosphine)-2-(2-aMinobiphenyl)]palladiuM(II)(1375325-71-5)Related Product Information

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• Chloro{[(1R,2R)-(-)-2-amino-1,2-diphenylethyl](4-toluenesulfonyl)amido}(mesitylene)ruthenium(II), min. 90% RuCl[(R,R)-Tsdpen(mesitylene)