Basic information Safety Supplier Related

AC-VDVAD-CHO

Basic information Safety Supplier Related

AC-VDVAD-CHO Basic information

Product Name:
AC-VDVAD-CHO
Synonyms:
  • CASPASE 2 INHIBITOR
  • CASPASE-2 INHIBITOR (ALDEHYDE)
  • CASPASE INHIBITOR VIII
  • Acetyl-valyl-aspartyl-valyl-alanyl-aspartal
  • ACETYL-L-VALYL-L-ASPARTYL-L-VALYL-L-ALANYL-L-ASPART-1-AL
  • AC-VAVAD-CHO
  • AC-VDVAD-ALDEHYDE
  • AC-VDVAD-CHO
CAS:
194022-51-0
MF:
C23H37N5O10
MW:
543.57
Product Categories:
  • peptides
Mol File:
194022-51-0.mol
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AC-VDVAD-CHO Chemical Properties

Boiling point:
996.6±65.0 °C(Predicted)
Density 
1.272±0.06 g/cm3(Predicted)
storage temp. 
−20°C
form 
solid
pka
4.19±0.10(Predicted)
Sequence
Ac-Val-Asp-Val-Ala-Asp-CHO
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Safety Information

WGK Germany 
3

MSDS

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AC-VDVAD-CHO Usage And Synthesis

Uses

Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC50: 46 and 15 nM)[1].

IC 50

Caspase-2: 46 nM (IC50); Caspase-3: 15 nM (IC50)

References

[1] Maillard MC, et al. Exploiting differences in caspase-2 and -3 S? subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19(19):5833-51. DOI:10.1016/j.bmc.2011.08.020

AC-VDVAD-CHOSupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
Shanghai Hanhong Scientific Co.,Ltd.
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Chemsky (shanghai) International Co.,Ltd
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BOC Sciences
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Hangzhou Peptidego Biotech Co.,Ltd.
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0571-87213919
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Eric@peptidego.com