AC-VEID-AMC Chemical Properties

Boiling point:

1106.8±65.0 °C(Predicted)

Density 

1.311±0.06 g/cm3(Predicted)

storage temp. 

−20°C

form 

powder

pka

4.09±0.10(Predicted)

color 

white

Appearance

Solid Powder

MSDS

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AC-VEID-AMC Usage And Synthesis

Description

Ac-VEID-AMC is a fluorogenic substrate for caspase-6 and related proteases including caspase-8. Caspase activity can be quantified by fluorescent detection of free AMC (7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.

Uses

Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm)[1].

References

[1] Benford HL, et al. Visualization of bisphosphonate-induced caspase-3 activity in apoptotic osteoclasts in vitro. Bone. 2001 May;28(5):465-73. DOI:10.1016/s8756-3282(01)00412-4

Excitation / Emission Maximum

340-360 nm/440-460 nm

Sequene

Ac-Val-Glu-Ile-Asp-AMC

AC-VEID-AMC(219137-97-0)Related Product Information

• AC-VDVAD-PNA
• Z-VAD-FMK
• AC-IETD-PNA
• AC-LEU-GLU-HIS-ASP-AMC
• Z-PHE-DL-ALA-FLUOROMETHYLKETONE
• AC-YVAD-PNA
• CASPASE INHIBITOR3
• Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE
• Z-YVAD-AFC
• ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL
• AC-VDVAD-CHO
• AC-DEVD-AFC
• PAC1
• AC-DEVD-CHO
• AC-IETD-CHO
• AC-LEHD-AFC
• AC-LEU-GLU-THR-ASP-AFC
• AC-VEID-AMC