AC-LEU-GLU-HIS-ASP-AMC
AC-LEU-GLU-HIS-ASP-AMC Basic information
- Product Name:
- AC-LEU-GLU-HIS-ASP-AMC
- Synonyms:
-
- N-ACETYL-LEU-GLU-HIS-ASP-7-AMINO-4-METHYLCOUMARIN AMC
- CASPASE-9 SUBSTRATE (FLUOROGENIC)
- ACETYL-L-LEUCYL-L-GLUTAMYL-L-HISTIDYL-L-ASPARTIC ACID ALPHA-(4-METHYLCOUMARYL-7-AMIDE)
- AC-LEHD-MCA
- AC-LEHD-AMC
- AC-LEHD-AMC TRIFLUOROACETATE SALT
- AC-LEU-GLU-HIS-ASP-7-AMINO-4-METHYLCOUMARIN
- AC-LEU-GLU-HIS-ASP-AMC
- CAS:
- 292633-16-0
- MF:
- C33H41N7O11
- MW:
- 711.72
- Product Categories:
-
- peptide
- Pepetides
- Mol File:
- 292633-16-0.mol
More
Less
AC-LEU-GLU-HIS-ASP-AMC Chemical Properties
- Boiling point:
- 1258.1±65.0 °C(Predicted)
- Density
- 1.388±0.06 g/cm3(Predicted)
- storage temp.
- -15°C
- solubility
- Water: 1 mg/ml
- form
- Lyophilized Powder
- pka
- 4.07±0.10(Predicted)
- color
- White to off-white
- Water Solubility
- 1mg/mL in water
More
Less
AC-LEU-GLU-HIS-ASP-AMC Usage And Synthesis
Description
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9. Ac-LEHD-AMC is cleaved by caspase-9 to release the fluorescent moiety AMC, which can be used to quantify caspase-9 activity.
Uses
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1].
References
[1] Igor M Prudnikov, et al. Short peptide tools for monitoring caspase and proteasome activities in embryonal and adult rat brain lysates: an approach for the differential identification of proteases. J Biochem. 2012 Mar;151(3):299-316. DOI:10.1093/jb/mvs001
Sequene
Ac-Leu-Glu-His-Asp-AMC
AC-LEU-GLU-HIS-ASP-AMCSupplier
GL Biochem (Shanghai) Ltd
- Tel
- 21-61263452 13641803416
- ymbetter@glbiochem.com
Beijing Ouhe Technology Co., Ltd
- Tel
- 010-010-82967028 13522913783
- 2355560935@qq.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Cellmano Biotech Limited
- Tel
- 0551-65326643 18156095617
- info@cellmano.com
More
Less
AC-LEU-GLU-HIS-ASP-AMC(292633-16-0)Related Product Information
- AC-VDVAD-PNA
- Z-VAD-FMK
- AC-YVAD-PNA
- CASPASE INHIBITOR3
- AC-VEID-AMC
- Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE
- Z-YVAD-AFC
- ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL
- AC-VDVAD-CHO
- AC-DEVD-AFC
- PAC1
- AC-DEVD-CHO
- AC-LEU-GLU-THR-ASP-AFC
- AC-LEHD-AFC
- AC-LEU-GLU-HIS-ASP-AMC
- AC-LEU-GLU-THR-ASP-AMC
- AC-LEU-GLU-VAL-ASP-AMC
- AC-LEU-GLU-HIS-ASP-AMC TFA SALT