POMALIDOMIDE-PEG1-CO2H

Product Name: POMALIDOMIDE-PEG1-CO2H
CAS No.: 2139348-60-8
Chemical Name: POMALIDOMIDE-PEG1-CO2H
Synonyms: 3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoic acid;Poma-PEG1-COOH;POMALIDOMIDE-PEG1-CO2H;Pomalidomide-PEG1-COOH;Pomalidomide-PEG1-C2-COOH;Pomalidomide 4'-PEG1-acid;Thalidomide-4-NH-PEG1-COOH;Thalidomide-NH-PEG1-C2-COOH;Pomalidomide-PEG1-CO2H >=95%;Thalidomide-4-NH-PEG1-C2-COOH
CBNumber: CB14743861
Molecular Formula: C18H19N3O7
Formula Weight: 389.36
MOL File: 2139348-60-8.mol

More

Less

POMALIDOMIDE-PEG1-CO2H Property

Boiling point:: 726.2±60.0 °C(Predicted)
Density: 1.508±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: powder or crystals
pka: 4.29±0.10(Predicted)
color: Yellow to brown

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 901527
Product name: Pomalidomide-PEG1-CO2H
Purity: ≥95%
Packaging: 50MG
Price: $1050
Updated: 2023/06/20

Iris Biotech GmbH

Product number: PTC1150
Product name: Pomalidomide-PEG1-COOH
Packaging: 50mg
Price: $702
Updated: 2021/12/16

More

Less

POMALIDOMIDE-PEG1-CO2H Chemical Properties,Usage,Production

Uses

Protein degrader builiding block Pomalidomide-PEG₁-CO₂H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

storage

Store at -20°C

POMALIDOMIDE-PEG1-CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

POMALIDOMIDE-PEG1-CO2H Suppliers

China 37 India 1 Japan 1 United States 1 Global 40

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7191
Advantage: 65

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 18112977050
Email: cb6@aikonchem.com
Country: China
ProdList: 16684
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
Advantage: 55

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4824
Advantage: 58

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1456
Advantage: 58

CR Corporation Limited

Tel: +8613062833949
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 8647
Advantage: 58

Wuhan Borenpharm Co., Ltd

Tel: 027-65563561 18717150066
Fax: 027-59218822
Email: 3207347307@qq.com
Country: CHINA
ProdList: 1238
Advantage: 58

Shaanxi borno biotechnology co., LTD

Tel: +86-13759708231
Email: asherw9@hotmail.com
Country: China
ProdList: 2350
Advantage: 58

Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD

Tel: 025-86755008 17751752005
Fax: 025-86755228
Email: hszhang@bestfluorodrug.com
Country: China
ProdList: 2358
Advantage: 58

Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 9990
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44808
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44458
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40037
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 18130062233
Email: 3362556465@qq.com
Country: China
ProdList: 7999
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62163
Advantage: 58

Xi'an Qiyue Biotechnology Co., Ltd.

Tel: 400-400-6966-012-012 17778955912
Email: 2957605606@qq.com
Country: China
ProdList: 2535
Advantage: 58

Changzhou Bojia Biomedical Technology Co., Ltd.

Tel: 2122619822
Email: czbjpharma@126.com
Country: China
ProdList: 18478
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24647
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054 13417589054
Email: trendseenbio@gmail.com
Country: China
ProdList: 9470
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD

Tel: 025-86755008 17751752005
Email: hszhang@bestfluorodrug.com
Country: China
ProdList: 2744
Advantage: 58

CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD

Tel: 17882285575
Email: 1276966012@qq.com
Country: China
ProdList: 339
Advantage: 58

Huanuo Pharmaceutical Technology (Guangxi) Co., Ltd

Tel: 13005928603
Email: 211017228@qq.com
Country: China
ProdList: 6615
Advantage: 58

Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

Tel: 021-59167510 18117107507
Email: vip@med-life.cn
Country: China
ProdList: 4997
Advantage: 58

Nanjing Bic Biotechnology Co., Ltd

Tel: 025-58906079 17352406906
Email: sales@bicbiotech.com
Country: China
ProdList: 7607
Advantage: 58

Shaoyuan Technology (Shanghai) Co., Ltd.

Tel: 021-50795510 4000665055
Email: sy-c6@accelachem.com
Country: China
ProdList: 10000
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: +86-18521732826
Email: market@aladdin-e.com
Country: China
ProdList: 48461
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: 18143011203
Email: ET-market@chemextension.com
Country: China
ProdList: 25831
Advantage: 58

Xi‘an Deeptech Biotechnology Co.,LTD

Tel: +86-15114901355 +86-15114901355
Email: 15114901355@163.com
Country: China
ProdList: 189
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Email: sales1@amateksci.com
Country: China
ProdList: 1526
Advantage: 58

Zhengzhou Lingzhiyue Technology Co., Ltd

Tel: +86-0371-55074660 +86-13783527580
Email: Lingzhiyue@aliyun.com
Country: China
ProdList: 3145
Advantage: 58

Suzhou ARTK Medchem Co., Ltd.

Tel: +86-512-68323658 +86-18168183658
Email: sales1@artkmedchem.com
Country: China
ProdList: 39004
Advantage: 58

Xian confluore Biological Technology Co., Ltd.

Tel: +86-15680926068 +86-15680926068
Email: 1924344760@confluore.cn
Country: China
ProdList: 2995
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

Nanjing Bicbiotechnology Co., Ltd

Tel: +86-2552131256 +86-18251840740
Email: sales@bicbiotech.com
Country: China
ProdList: 5994
Advantage: 58

LEAPCHEM CO., LTD.

Tel: +86-852-30606658
Email: market18@leapchem.com
Country: China
ProdList: 43340
Advantage: 58

More

Less

View Lastest Price from POMALIDOMIDE-PEG1-CO2H manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Pomalidomide-PEG1-COOH 2139348-60-8
Price: US $0.00/mg
Min. Order: 250mg
Purity: >99.00%
Supply Ability: 250mg
Release date: 2024-04-01

2139348-60-8, POMALIDOMIDE-PEG1-CO2HRelated Search:

Pomalidomide-PEG4-CO2H Pomalidomide-PEG3-CO2H POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG1-azide Pomalidomide-O-C4-NH2 Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]- Pomalidomide-PEG3-N3 Pomalidomide-PEG6-butyl iodide Pomalidomide-PEG5-CO2H E3 ligase Ligand-Linker Conjugates 50 Pomalidomide-PEG3-Amine HCl salt E3 Ligase Ligand-Linker Conjugates 1 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione E3 Ligase Ligand-Linker Conjugates 22 Pomalidomide-PEG2-butyl iodide Pomalidomide-PEG4-azide Pomalidomide-PEG2-N3 POMALIDOMIDE-PEG1-ALKYNE

POMALIDOMIDE-PEG1-CO2H

Pomalidomide-PEG1-CO2H >=95%

Pomalidomide-PEG1-COOH

Pomalidomide-PEG1-C2-COOH

3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoic acid

Thalidomide-4-NH-PEG1-COOH

Thalidomide-NH-PEG1-C2-COOH

Propanoic acid, 3-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]-

3-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoic acid, Crosslinker–E3 Ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader

Thalidomide-4-NH-PEG1-C2-COOH

Poma-PEG1-COOH

Pomalidomide 4'-PEG1-acid

3-[2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]ethoxy]propanoic Acid

3-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)propanoic acid

2139348-60-8

peg