ChemicalBook > CAS DataBase List > Propargyl-PEG4-bromide
Propargyl-PEG4-bromide
- Product Name
- Propargyl-PEG4-bromide
- CAS No.
- 1308299-09-3
- Chemical Name
- Propargyl-PEG4-bromide
- Synonyms
- Alkyne-PEG4-Br;PROPARGYL-PEG4-BR;Propargyl-PEG4-bromide;1-Bromo-3,6,9,12-tetraoxapentadec-14-yne;3,6,9,12-Tetraoxapentadec-14-yne, 1-bromo-;3-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]prop-1-yne;Propargyl-PEG4-Br/3,6,9,12-Tetraoxapentadec-14-yne, 1-bromo-
- CBNumber
- CB33062624
- Molecular Formula
- C11H19BrO4
- Formula Weight
- 295.17
- MOL File
- 1308299-09-3.mol
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Propargyl-PEG4-bromide Property
- Boiling point:
- 334.3±32.0 °C(Predicted)
- Density
- 1.269±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
TRC
- Product number
- P839568
- Product name
- Propargyl-PEG4-bromide
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22782
- Product name
- Propargyl-PEG4-bromide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $420
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22782
- Product name
- Propargyl-PEG4-bromide
- Purity
- 98%
- Packaging
- 500mg
- Price
- $580
- Updated
- 2021/12/16
Apolloscientific
- Product number
- BIPG1730
- Product name
- Propargyl-PEG4-bromide
- Packaging
- 250mg
- Price
- $817
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22782
- Product name
- Propargyl-PEG4-bromide
- Purity
- 98%
- Packaging
- 1g
- Price
- $950
- Updated
- 2021/12/16
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Propargyl-PEG4-bromide Chemical Properties,Usage,Production
Description
Propargyl-PEG4-bromide is a crosslinker that can be used in copper catalyzed azide-alkyne Click Chemistry to form a stable triazole linkage with azides. The bromide (Br) acts as a good leaving group for nucleophilic substitution reactions.
Uses
Propargyl-PEG4-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG4-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
Non-cleavable Linker; PEGs
References
[1] Suzanne AKERS-RODRIGUEZ, et al. Compositions and methods for the treatment of bacterial infections. WO2019126353A2.
Propargyl-PEG4-bromide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Propargyl-PEG4-bromide manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Propargyl-PEG4-bromide 1308299-09-3
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-26
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