Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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Organic reagents

Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.

After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.

8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.

Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.

Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.

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Structure:
Chemical Name:
3-(Tetrahydropyran-2-yloxy)phenylboronic acid
CAS:
1287777-05-2
MF:
C11H15BO4
Structure:
Chemical Name:
1,6-Dimethyl-1H-indazole-4-boronic acid
CAS:
1310405-32-3
MF:
C9H11BN2O2
Structure:
Chemical Name:
1,3-Dimethyl-1H-indazole-7-boronic acid
CAS:
1309982-19-1
MF:
C9H11BN2O2
Structure:
Chemical Name:
Methyl 4-amino-3-methoxybenzoate
CAS:
41608-64-4
MF:
C9H11NO3
Structure:
Chemical Name:
1H-Indole-1-carboxylic acid, 2-borono-4-fluoro-, 1-(1,1-dimethylethyl) ester
CAS:
1000068-25-6
MF:
C13H15BFNO4
Structure:
Chemical Name:
Ethyl 3-oxo-4-phenylbutanoate
CAS:
718-08-1
MF:
C12H14O3
Structure:
Chemical Name:
2-(6-Methyl-4,8-dioxo-1,3,6,2-dioxazaborocan-2-yl)benzaldehyde
CAS:
1257651-51-6
MF:
C12H12BNO5
Structure:
Chemical Name:
2-(Benzofuran-2-yl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione, 2-Benzofuranboronic acid MIDA ester
CAS:
1104637-65-1
MF:
C13H12BNO5
Structure:
Chemical Name:
2,3,5,6-TETRAMETHYLPHENYLBORONIC ACID
CAS:
197223-36-2
MF:
C10H15BO2
Structure:
Chemical Name:
PRL-8-53
CAS:
51352-87-5
MF:
C18H22ClNO2
Structure:
Chemical Name:
Hexanedioic acid dihexyl ester
CAS:
110-33-8
MF:
C18H34O4
Structure:
Chemical Name:
4-tert-Butoxystyrene
CAS:
95418-58-9
MF:
C12H16O
Structure:
Chemical Name:
3-BROMOBENZENEBORONIC ACID N-METHYLDIETHANOLAMINE ESTER
CAS:
374538-00-8
MF:
C11H15BBrNO2
Structure:
Chemical Name:
Tetraethylammonium fluoride dihydrate
CAS:
665-46-3
MF:
C8H24FNO2
Structure:
Chemical Name:
1-BROMO-3-CHLORO-2-FLUOROBENZENE
CAS:
144584-65-6
MF:
C6H3BrClF
Structure:
Chemical Name:
BUTYL TRIMETHYLAMMONIUM BROMIDE
CAS:
2650-51-3
MF:
C7H18N.Br
Structure:
Chemical Name:
5-tetradecyloxolan-2-one
CAS:
502-26-1
MF:
C18H34O2
Structure:
Chemical Name:
N-Methoxy-N-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
CAS:
957061-17-5
MF:
C15H22BNO4
Structure:
Chemical Name:
Dodecanedioic Dihydrazide
CAS:
4080-98-2
MF:
C12H26N4O2
Structure:
Chemical Name:
2-[2-(Dimethylamino)ethoxy]ethanol
CAS:
1704-62-7
MF:
C6H15NO2
Structure:
Chemical Name:
1-AMINO-3-METHYLBUTANE HYDROCHLORIDE
CAS:
541-23-1
MF:
C5H14ClN
Structure:
Chemical Name:
1,3-Diisopropylimidazolium tetrafluoroborate
CAS:
286014-34-4
MF:
C9H17BF4N2
Structure:
Chemical Name:
TRANS-2-(4-(TRIFLUOROMETHYL)PHENYL)-
CAS:
352525-91-8
MF:
C9H8BF3O2
Structure:
Chemical Name:
TRANS-2-(4-BIPHENYL)VINYLBORONIC ACID
CAS:
352530-23-5
MF:
C14H13BO2
Structure:
Chemical Name:
Triphenylsulfonium nonaflate
CAS:
144317-44-2
MF:
C22H15F9O3S2
Structure:
Chemical Name:
E-2-(2 4-DIFLUOROPHENYL)VINYLBORONIC AC&
CAS:
736987-78-3
MF:
C14H17BF2O2
Structure:
Chemical Name:
4-(4-Methylthiophenyl)phenylboronic acid
CAS:
1771775-13-3
MF:
C24H24BNO2S
Chemical Name:
Coco trimethyl ammonium chloride
Structure:
Chemical Name:
Dihexadecyldimethylammonium chloride
MF:
C34H72ClN
Chemical Name:
0.1% methyl orange indicator
Structure:
Chemical Name:
6FCDA
CAS:
139162-14-4
MF:
C19H4F6O7
Chemical Name:
Ethylene glycol (1,2-ethylene glycol)
Structure:
Chemical Name:
1-(PHENYLSULFONYL)-1H-INDOL-3-YLBORONIC ACID
CAS:
129271-98-3
MF:
C14H12BNO4S
Structure:
Chemical Name:
1-(PHENYLSULFONYL)-1H-INDOL-3-YLBORONIC ACID
CAS:
129271-98-3
MF:
C14H12BNO4S
Structure:
Chemical Name:
1-(PHENYLSULFONYL)-1H-INDOL-3-YLBORONIC ACID
CAS:
129271-98-3
MF:
C14H12BNO4S
Structure:
Chemical Name:
1,1,1-Trifluoro-4-iodobutane
CAS:
461-17-6
MF:
C4H6F3I
Structure:
Chemical Name:
tert-Butyl trimethylacetate
CAS:
16474-43-4
MF:
C9H18O2
Structure:
Chemical Name:
1,3-Bis(2,4,6-trimethylphenyl)imidazolium chloride
CAS:
141556-45-8
MF:
C21H25ClN2
Chemical Name:
NA
Structure:
Chemical Name:
3-Hydroxy-1,8-naphthalic anhydride
CAS:
23204-36-6
MF:
C12H6O4
Structure:
Chemical Name:
4-(1'-CARBOXYL-CYCLOPROPYL)PHENYLBORONIC ACID
CAS:
1159489-46-9
MF:
C10H11BO4
Structure:
Chemical Name:
2,2':5,2''-terthiophene-5,5''-diboronic acid
CAS:
853685-99-1
MF:
C12H10B2O4S3
Structure:
Chemical Name:
4,4-(DIMETHYLCYCLOHEX-2-ENONE)-2-BORONIC ACID, PINACOL ESTER
CAS:
219489-09-5
MF:
C14H23BO3
Chemical Name:
CAFLON OAT
Structure:
Chemical Name:
2-METHOXY-5-METHOXYCARBONYLPHENYLBORONIC ACID, PINACOL ESTER
CAS:
269410-10-8
MF:
C15H21BO5
Structure:
Chemical Name:
Boronic acid, B-[5-(1,1-dimethylethyl)-2-hydroxyphenyl]-
CAS:
259209-27-3
MF:
C10H15BO3
Structure:
Chemical Name:
[2-(diphenylmethoxy)ethyl]trimethylammonium bromide
CAS:
31065-89-1
MF:
C18H24BrNO
Structure:
Chemical Name:
dimethylbis[2-[(1-oxohexadecyl)oxy]ethyl]ammonium chloride
CAS:
97158-31-1
MF:
C38H76ClNO4
Structure:
Chemical Name:
Trimethylchloromethylammonium,chloride
CAS:
21478-66-0
MF:
C4H11Cl2N
Structure:
Chemical Name:
HEXYLBORONIC ACID PINACOL ESTER
CAS:
86308-26-1
MF:
C12H25BO2
Structure:
Chemical Name:
Boronic acid, B-[4-[bis[4-(diphenylamino)phenyl]amino]phenyl]-
CAS:
2092470-74-9
MF:
C42H34BN3O2
Structure:
Chemical Name:
Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate
CAS:
1035490-58-4
MF:
C13H18FNO3
Structure:
Chemical Name:
Triazine
MF:
C3H3N3
Structure:
Chemical Name:
1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-[3-(spiro[cyclohexane-1,9'-[9H]fluoren]-2'-yl)phenyl]-
CAS:
2757253-64-6
MF:
C30H33BO2
Structure:
Chemical Name:
(2-METHYL-1,3-BENZOXAZOL-6-YL)BORONIC ACID
CAS:
866332-15-2
MF:
C8H8BNO3
Structure:
Chemical Name:
3-(2,3-DifluorophenylMethoxy)phenylboronic acid
CAS:
1256358-50-5
MF:
C13H11BF2O3
Structure:
Chemical Name:
4-Chloro-1h-indole-2-boronic acid
CAS:
1256355-59-5
MF:
C8H7BClNO2
Structure:
Chemical Name:
Ethyl-2-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3- enyl)acetate
CAS:
1166829-70-4
MF:
C16H27BO4
Structure:
Chemical Name:
3-Bromo-2-chlorophenol
CAS:
863870-87-5
MF:
C6H4BrClO
Structure:
Chemical Name:
Quinoline, 2-phenyl-7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
CAS:
867164-54-3
MF:
C21H22BNO2
Structure:
Chemical Name:
3-Chloro-2,4-difluorophenylboronic acid
CAS:
1310384-18-9
MF:
C6H4BClF2O2
Structure:
Chemical Name:
METHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE
CAS:
162085-97-4
MF:
C6H9N3O2
Structure:
Chemical Name:
1-bromodibenzo[b,d]furan
CAS:
50548-45-3
MF:
C12H7BrO
Structure:
Chemical Name:
2-Methoxy-4-(Methoxycarbonyl)phenylboronic acid
CAS:
849758-14-1
MF:
C9H11BO5
Structure:
Chemical Name:
2-tert-ButyloxycarbonylaMino-3-Methylpyridine-5-boronic acid
CAS:
1356087-58-5
MF:
C11H17BN2O4
Structure:
Chemical Name:
4,4,5,5-TetraMethyl-2-(3-triphenylen-2-yl-phenyl)-[1,3,2]dioxaborolane
CAS:
890042-13-4
MF:
C24H23BO2
Structure:
Chemical Name:
Tricyclo[3.3.1.13,7]decan-1-aminium, N,N,N-trimethyl-, chloride (1:1)
CAS:
128346-46-3
MF:
C13H24N.Cl
Structure:
Chemical Name:
(R)-(2,2'-Dimethoxy-[1,1'-binaphthalene]-3,3'-diyl)diboronic acid
CAS:
215433-49-1
MF:
C22H20B2O6
Structure:
Chemical Name:
Bromotriphenyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)phosphorane
CAS:
1169942-85-1
MF:
C31H33BBrO2P
Structure:
Chemical Name:
4-[2-(2,4-DiMethylphenylsulfanyl)phenyl]piperazine-1-carboxylic acid tert-butyl ester
CAS:
960203-42-3
MF:
C23H30N2O2S
Structure:
Chemical Name:
(R)-2-Methylpyrrolidine benzenesulfonate
CAS:
896743-24-1
MF:
C11H17NO3S
Structure:
Chemical Name:
1-Methylcyclopentyl methacrylate
CAS:
178889-45-7
MF:
C10H16O2
Structure:
Chemical Name:
3,5-dichloro-4-hydroxyphenylboronic acid
CAS:
1335048-35-5
MF:
C6H5BCl2O3
Structure:
Chemical Name:
4-TERT-BUTOXYMETHYLPHENYLBORONIC ACID
CAS:
1024017-53-5
MF:
C11H17BO3
Structure:
Chemical Name:
Tetrahydrofurfuryl acrylate
CAS:
2399-48-6
MF:
C8H12O3
Structure:
Chemical Name:
1,2-Diphenyl-1,2-dicarba-closo-dodecaborane
CAS:
17805-19-5
MF:
C14H10B10
Structure:
Chemical Name:
2,6-diethyl-4-methylphenylboronic acid
CAS:
953075-90-6
MF:
C11H17BO2
Structure:
Chemical Name:
Trifluoroacetonitrile
CAS:
353-85-5
MF:
C2F3N
Structure:
Chemical Name:
(4-(4-Nitrophenoxy)phenyl)boronic acid
CAS:
1072945-82-4
MF:
C12H10BNO5
Chemical Name:
mPEG24-Br
Structure:
Chemical Name:
2,4-dihydroxy-6-ethylbenzoic acid, methyl ester
CAS:
102342-60-9
MF:
C10H12O4
Structure:
Chemical Name:
β-Methylcholine Chloride
CAS:
2382-43-6
MF:
C6H16ClNO
Chemical Name:
Cal Green 1, AM [Equivalent to Calcium Green -1, AM]
Structure:
Chemical Name:
B-[3-(3,6-dimethyl-9H-carbazol-9-yl)phenyl]-Boronic acid
CAS:
1221252-59-0
MF:
C20H18BNO2
Structure:
Chemical Name:
2-METHYLGLUTARONITRILE
CAS:
4553-62-2
MF:
C6H8N2
Structure:
Chemical Name:
TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER
CAS:
15177-67-0
MF:
C9H14O4
Structure:
Chemical Name:
2,3-DICHLORO-5,8-DIHYDROXY-1,4-NAPHTHOQUINONE
CAS:
14918-69-5
MF:
C10H4Cl2O4
Structure:
Chemical Name:
DYSPROSIUM (III) ISOPROPOXIDE
CAS:
6742-68-3
MF:
C3H8DyO
Structure:
Chemical Name:
3,3'-DIMETHOXYBENZIL
CAS:
40101-17-5
MF:
C16H14O4
Structure:
Chemical Name:
(11bS)- 2,6-bis[2,6-bis(1-methylethyl)-4-tricyclo[3.3.1.13,7]dec-1-ylphenyl]-4-hydroxy-4-oxide-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin
CAS:
1087345-30-9
MF:
C64H73O4P
Structure:
Chemical Name:
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, boron complex
CAS:
74231-02-0
MF:
C18H15BO21-6
Structure:
Chemical Name:
ETHYLTRI-N-PROPYLAMMONIUM IODIDE
CAS:
15066-80-5
MF:
C11H26IN
Structure:
Chemical Name:
2-METHOXY-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL ACETATE
CAS:
811841-45-9
MF:
C15H21BO5
Structure:
Chemical Name:
3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE
CAS:
198479-63-9
MF:
C29H25NO2
Structure:
Chemical Name:
(5-BROMO-2-HYDROXY)BENZENEBORONIC ACID
CAS:
89598-97-0
MF:
C6H6BBrO3
Structure:
Chemical Name:
2-(4-METHOXYPHENYL)-VINYLBORONIC ACID PINACOL ESTER
CAS:
149777-83-3
MF:
C15H21BO3
Structure:
Chemical Name:
Urolithin B
CAS:
1139-83-9
MF:
C13H8O3
Structure:
Chemical Name:
Methyl 2-iodobenzoate
CAS:
610-97-9
MF:
C8H7IO2
Structure:
Chemical Name:
TRANS-2-(4-METHYLPHENYL)VINYLBORONIC AC&
CAS:
72316-17-7
MF:
C9H11BO2
Structure:
Chemical Name:
Palatinose
CAS:
58166-27-1
MF:
C12H22O11