Amino-PEG1-t-Butyl ester Chemical Properties

Boiling point:

264.9±15.0 °C(Predicted)

Density 

0.992±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Oil

pka

8.73±0.10(Predicted)

color 

Clear Colourless to Pale Yellow to Dark Yellow

Amino-PEG1-t-Butyl ester Usage And Synthesis

Description

Amino-PEG1-t-butyl ester is a PEG reagent containing an amino group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-Boc group can be deprotected under acidic conditions.

Uses

Amino-peg1-t-butyl Ester is a reagent used in the preparation of β2 adrenergic receptor agonists and muscarinic receptor activity antagonists.

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