PROTAC ER Degrader-3
PROTAC ER Degrader-3 Basic information
- Product Name:
- PROTAC ER Degrader-3
- Synonyms:
-
- PROTAC ER Degrader-3
- Carbamic acid, N-[(1S)-2-[[(3S,4S)-7-cyano-2,3,4,5-tetrahydro-5-[4-[[[2-[2-[2-[[2-[4-[1-(4-hydroxyphenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]methylamino]-2-oxoethoxy]ethoxy]ethyl]amino]carbonyl]benzoyl]-1-[(2-methoxy-1-naphthalenyl)methyl]-4-methyl-2-oxo-1H-1,5-benzodiazepin-3-yl]amino]-1-methyl-2-...
- Carbamic acid, N-[(1S)-2-[[(3S,4S)-7-cyano-2,3,4,5-tetrahydro-5-[4-[[[2-[2-[2-[[2-[4-[1-(4-hydroxyphenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]methylamino]-2-oxoethoxy]ethoxy]ethyl]amino]carbonyl]benzoyl]-1-[(2-methoxy-1-naphthalenyl)methyl]-4-methyl-2-oxo-1H-1,5-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-N-methyl-, 1,1-dimethylethyl ester
- CAS:
- 2158322-29-1
- MF:
- C71H77N7O12
- MW:
- 1220.43
- Mol File:
- 2158322-29-1.mol
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PROTAC ER Degrader-3 Chemical Properties
- Boiling point:
- 1264.4±65.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 9.38±0.15(Predicted)
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PROTAC ER Degrader-3 Usage And Synthesis
Description
PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC comprises an antibody conjugated via a linker to a PROTAC. PAC extracts from patent WO2017201449A1, compound LP2. PAC is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).
References
[1]. Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1.
PROTAC ER Degrader-3Supplier
Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel
- 028-81700200 18116577057
- 3003855609@qq.com
Jilin Province Woda Biotechnology Co., Ltd.
- Tel
- 13504435624
- 1927928688@qq.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
Changzhou Bojia Biomedical Technology Co., Ltd.
- Tel
- 2122619822
- czbjpharma@126.com
ShenZhen Trendseen Biological Technology Co.,Ltd.
- Tel
- 13417589054 13417589054
- trendseenbio@gmail.com
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