Enalapril

Product Name: Enalapril
CAS No.: 75847-73-3
Chemical Name: Enalapril
Synonyms: Vasotec;Renitec;G1ioten;Hipoartd;ENALAPRIL;Enalapril hydrate;Enalapril (MK-421);ELAPRILAT DIHYDRAT;Enalapril USP/EP/BP;Enalapril AldrichCPR
CBNumber: CB1295108
Molecular Formula: C20H28N2O5
Formula Weight: 376.45
MOL File: 75847-73-3.mol

More

Less

Enalapril Property

Melting point:: 142-147℃
Boiling point:: 582.4±50.0 °C(Predicted)
Density: 1.204±0.06 g/cm3(Predicted)
RTECS: TW3665500
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Soluble in DMSO
form: Powder
pka: pKa 2.97 (H2O t=25.0)(Approximate);5.35(H2O t=25.0)(Approximate)
Water Solubility: Soluble in water at 25mg/ml
BCS Class: 3
CAS DataBase Reference: 75847-73-3(CAS DataBase Reference)
EPA Substance Registry System: L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl- (75847-73-3)

More

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3
Hazardous Substances Data: 75847-73-3(Hazardous Substances Data)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Alfa Aesar

Product number: J60750
Product name: Enalapril
Packaging: 1g
Price: $93.65
Updated: 2024/03/01

Alfa Aesar

Product number: J60750
Product name: Enalapril
Packaging: 5g
Price: $369.65
Updated: 2024/03/01

Cayman Chemical

Product number: 16041
Product name: Enalapril
Purity: ≥98%
Packaging: 5g
Price: $165
Updated: 2021/12/16

Cayman Chemical

Product number: 16041
Product name: Enalapril
Purity: ≥98%
Packaging: 1g
Price: $48
Updated: 2021/12/16

Cayman Chemical

Product number: 16041
Product name: Enalapril
Purity: ≥98%
Packaging: 10g
Price: $270
Updated: 2021/12/16

More

Less

Enalapril Chemical Properties,Usage,Production

Uses

angiotensin converting enzyme inhibitor

Uses

It is used for hypertension and chronic cardiac insufficiency.

Uses

Enalapril is used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. It has been proven to protect the function of the kidneys in hypertension, heart failure, and diabetes, and may be used in the absence of hypertension for its kidney protective effects. It is widely used in chronic kidney failure.

Definition

ChEBI: A dicarboxylic acid monoester that is ethyl 4-phenylbutanoate in which a hydrogen alpha to the carboxy group is substituted by the amino group of L-alanyl-L-proline (S-configuration).

Mechanism of action

Like captopril, enalapril selectively suppresses the rennin–angiotensin–aldosterone system, inhibits angiotensin-converting enzyme, and prevents conversion of angiotensin I into angiotensin II.

Synthesis

Enalapril, (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline (22.7.12), is synthesized by reacting the benzyl ester of L-alanyl-L-proline with the ethyl ester of 3-benzoylacrylic acid, which forms the product 22.7.11, the reduction of which with hydrogen using a Raney nickel catalyst removes the protective benzyl group, giving the desired enalapril (22.7.12) [24]. Alternative methods of syntheses have also been proposed.

Enalapril Preparation Products And Raw materials

Raw materials

N-Hydroxysuccinimide Enalapril maleate Palladium carbon fine chemical catalyzer Benzyl ester Ethyl 2-oxo-4-phenylbutyrate Maleic acid Maleic anhydride PROPYLENE dipeptide L-Alanyl-L-proline Water L-Proline Bromobenzene Concentrated sulfuric acid Benzene Ethyl acetate D-Alanine Acetic acid Ethyl acrylate DOWEX(R) 50WX4 HYDROGEN FORM Sodium cyanoborohydride Dicyclohexylcarbodiimide Formamide

Preparation Products

More

Less

Enalapril Suppliers

Bangladesh 1 Belgium 1 Brazil 1 Canada 2 China 112 Europe 1 France 2 Germany 7 India 16 South Korea 2 Switzerland 1 The Netherlands 1 United Kingdom 11 United States 33 Global 191

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

EJY Tech, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 448
Advantage: 30

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6962
Advantage: 56

MilliporeSigma (Sigma-Aldrich Corp.)

Tel: --
Fax: --
Email: @sial.com
Country: United States
ProdList: 5414
Advantage: 58

Ontario Chemicals, Inc

Tel: --
Fax: --
Email: info@ontariochem.com
Country: United States
ProdList: 723
Advantage: 50

OChem Incorporation

Tel: --
Fax: --
Email: sales@ocheminc.com
Country: United States
ProdList: 6501
Advantage: 60

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

AlliChem, LLC

Tel: --
Fax: --
Email: sales@allichemllc.com
Country: United States
ProdList: 6516
Advantage: 60

Fragmenta

Tel: --
Fax: --
Email: sales@fragmenta.com
Country: United States
ProdList: 1068
Advantage: 0

Santa Cruz Biotechnology, Inc.

Tel: --
Fax: --
Email: scbt@scbt.com
Country: United States
ProdList: 3597
Advantage: 60

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

Molcan Corporation

Tel: --
Fax: --
Email: info@molcan.com
Country: United States
ProdList: 686
Advantage: 60

LKT Laboratories, Inc.

Tel: --
Fax: --
Email: info@lktlabs.com
Country: United States
ProdList: 2164
Advantage: 64

ECA International Corporation

Tel: --
Fax: --
Email: services@ecacorporation.com
Country: United States
ProdList: 1062
Advantage: 52

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

Sinova Inc.

Tel: --
Fax: --
Email: sales@sinovainc.com
Country: United States
ProdList: 4009
Advantage: 58

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

APAC Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@apacpharma.com
Country: United States
ProdList: 6322
Advantage: 38

SynFine Research

Tel: --
Fax: --
Email: research@synfine.com
Country: United States
ProdList: 1024
Advantage: 68

American Custom Chemicals Corporation

Tel: --
Fax: --
Email: sales@acccorporation.com
Country: United States
ProdList: 6820
Advantage: 51

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

Alltech Associates, Inc.

Tel: --
Fax: --
Email: alltech@alltechemail.com
Country: United States
ProdList: 419
Advantage: 60

More

Less

View Lastest Price from Enalapril manufacturers

Sinoway Industrial co., ltd.

Product: Enalapril 75847-73-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-04-28

Zhuozhou Wenxi import and Export Co., Ltd

Product: Enalapril 75847-73-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: Enalapril 75847-73-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

75847-73-3, EnalaprilRelated Search:

cis-4-Hydroxy-L-proline Ethyl acrylate L-PROLINE-(4-3H(N)) Ethylbenzene Ethylparaben D-Proline Tris(trimethylsilyl)phosphate Ethanol Ethyl acetate ENALAPRILAT-D5 ENALAPRILAT-D5, SODIUM SALT Trandolapril Indolapril N2-1[(1S)-Ethoxycarbonyl-3-phenylpropyl]-N6-trifluoroacetyl-L-lysyl-L-proline Spirapril Enalapril maleate Diethyl ether Enalapril-D5 tert-Butyl Ester

ENALAPRIL

(s)-1-(n-(1-(ethoxycarbonyl)-3-phenylpropyl)-l-alanyl)-l-proline

1-(n-((s)-1-carboxy-3-phenylpropyl)-l-alanyl)-l-proline 1'-ethyl ester

1-[2-(1-ETHOXYCARBONYL-3-PHENYL-PROPYL)AMINOPROPANOYL]PYRROLIDINE-2-CARBOXYLIC ACID

N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline

Renitec

Vasotec

Enalapril Maleate USP24

L-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, (S)-

L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-

(-)-1-[N-[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline

1-[N-[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline

N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-Ala-L-Pro-OH

N-[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-Ala-L-Pro-OH

(S)-1-((S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)aMino)propanoyl)pyrrolidine-2-carboxylic acid

Enalapril AldrichCPR

(S)-1-[N-[1-(Ethoxyearbonyl)-3-phenylpropyl]-L-alanyl]-L-proline

G1ioten

Hipoartd

(2S)-1-[(2S)-2-[[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid

(S)-N-[1-Ethoxycarbonyl)-3-phenylpropyl]-Ala-Pro

Enalapril hydrate

Enalapril USP/EP/BP

Enalaprilat dihydrat

EnalaprilQ: What is Enalapril Q: What is the CAS Number of Enalapril Q: What is the storage condition of Enalapril Q: What are the applications of Enalapril

Enalapril (MK-421)

ELAPRILAT DIHYDRAT

75847-73-3

C20H28N2O5

Angiotensin