ChemicalBook > CAS DataBase List > Propargyl-PEG4-methylamine
Propargyl-PEG4-methylamine
- Product Name
- Propargyl-PEG4-methylamine
- CAS No.
- 1807530-11-5
- Chemical Name
- Propargyl-PEG4-methylamine
- Synonyms
- Alkyne-PEG4-MEA;PROPARGYL-PEG4-MEA;Propargyl-PEG4-NHMe;Propargyl-PEG4-methylamine;3,6,9,12-Tetraoxapentadec-14-yn-1-amine, N-methyl-
- CBNumber
- CB23062627
- Molecular Formula
- C12H23NO4
- Formula Weight
- 245.32
- MOL File
- 1807530-11-5.mol
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Propargyl-PEG4-methylamine Property
- Boiling point:
- 317.1±32.0 °C(Predicted)
- Density
- 1.002±0.06 g/cm3(Predicted)
- solubility
- Soluble in Water, DMSO, DMF, DCM
- pka
- 9.52±0.10(Predicted)
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-22831
- Product name
- Propargyl-PEG4-methylamine
- Purity
- 98%
- Packaging
- 100mg
- Price
- $360
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22831
- Product name
- Propargyl-PEG4-methylamine
- Purity
- 98%
- Packaging
- 250mg
- Price
- $680
- Updated
- 2021/12/16
Apolloscientific
- Product number
- BIPG1733
- Product name
- Propargyl-PEG4-methylamine
- Packaging
- 100mg
- Price
- $701
- Updated
- 2021/12/16
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Propargyl-PEG4-methylamine Chemical Properties,Usage,Production
Description
Propargyl-PEG4-methylamine is a PEG linker that can be react with azide compounds in copper catalyzed azide-alkyne Click Chemistry reactions. The methylamine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The PEG spacer increases hydrophilicity of the linker in aqueous environment.
Uses
Propargyl-PEG4-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-methylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Propargyl-PEG4-methylamine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Propargyl-PEG4-methylamine manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Propargyl-PEG4-methylamine 1807530-11-5
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-26
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