POMALIDOMIDE-PEG2-CO2H
- Product Name
- POMALIDOMIDE-PEG2-CO2H
- CAS No.
- 2140807-17-4
- Chemical Name
- POMALIDOMIDE-PEG2-CO2H
- Synonyms
- NUN 07174;Poma-PEG2-COOH;Pomalidomide-PEG2-COOH;POMALIDOMIDE-PEG2-CO2H;Pomalidomide-PEG2-Acid;Pomalidomide 4'-PEG2-acid;Thalidomide-4-NH-PEG2-COOH;Thalidomide-NH-PEG2-C2-COOH;Pomalidomide-PEG2-CO2H >=98%;Thalidomide-4-NH-PEG2-C2-COOH
- CBNumber
- CB44744117
- Molecular Formula
- C20H23N3O8
- Formula Weight
- 433.41
- MOL File
- 2140807-17-4.mol
POMALIDOMIDE-PEG2-CO2H Property
- Boiling point:
- 744.6±60.0 °C(Predicted)
- Density
- 1.456±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- powder or crystals
- pka
- 4.28±0.10(Predicted)
- color
- White to yellow
N-Bromosuccinimide Price
- Product number
- 901526
- Product name
- Pomalidomide-PEG2-CO2H
- Purity
- 95%
- Packaging
- 50MG
- Price
- $1070
- Updated
- 2023/06/20
- Product number
- PTC1160
- Product name
- Pomalidomide-PEG2-COOH
- Packaging
- 50mg
- Price
- $702
- Updated
- 2021/12/16
POMALIDOMIDE-PEG2-CO2H Chemical Properties,Usage,Production
Uses
Protein degrader builiding block Pomalidomide-PEG2-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.
storage
Store at -20°C
POMALIDOMIDE-PEG2-CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
POMALIDOMIDE-PEG2-CO2H Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32165
- Advantage
- 58
- Tel
- +1-+1(833)-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58
View Lastest Price from POMALIDOMIDE-PEG2-CO2H manufacturers
- Product
- Pomalidomide-PEG2-COOH 2140807-17-4
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >99.00%
- Supply Ability
- 100mg
- Release date
- 2024-04-01