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Propargyl-PEG3-Bromide

Product Name
Propargyl-PEG3-Bromide
CAS No.
203740-63-0
Chemical Name
Propargyl-PEG3-Bromide
Synonyms
Alkyne-PEG3-Br;PROPARGYL-PEG3-BR;Propargyl-PEG3-Bromide;3-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)prop-1-yne;1-Propyne, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-;3- (2- (2- (2-bromoethoxy) ethoxy) ethoxy) propa-1-yne;Propargyl-PEG3-Br/1-Propyne, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-
CBNumber
CB73062622
Molecular Formula
C9H15BrO3
Formula Weight
251.12
MOL File
203740-63-0.mol
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Propargyl-PEG3-Bromide Property

Boiling point:
287.8±25.0 °C(Predicted)
Density 
1.300±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, stored under nitrogen, away from moisture
solubility 
Soluble in DMSO, DCM, DMF
form 
Liquid
color 
Colorless to light yellow
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Safety

HS Code 
2942000090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22738
Product name
Propargyl-PEG3-bromide
Purity
98%
Packaging
250mg
Price
$350
Updated
2021/12/16
BroadPharm
Product number
BP-22738
Product name
Propargyl-PEG3-bromide
Purity
98%
Packaging
1g
Price
$890
Updated
2021/12/16
Acrotein
Product number
B-1405
Product name
Propargyl-PEG3-Br
Purity
97%
Packaging
1g
Price
$412.5
Updated
2021/12/16
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Propargyl-PEG3-Bromide Chemical Properties,Usage,Production

Description

Propargyl-PEG3-bromide comprises a propargyl group and a bromide group. The propargyl group reacts with azide-bearing compounds or biomolecules in Click Chemistry to yield a stable triazole linkage; copper will be needed as a catalyst.

Uses

Propargyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Propargyl-PEG3-Bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG3-Bromide Suppliers

China 48 United Kingdom 1 United States 3 Global 52
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from Propargyl-PEG3-Bromide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG3-bromide 203740-63-0
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-26

203740-63-0, Propargyl-PEG3-BromideRelated Search:

Aminooxy-PEG4-Propargyl Aminoxy-PEG3-Propargyl Propargyl-PEG7-acid Aminooxy-PEG1-propargyl Propargyl-PEG6-acid Propargyl-PEG4-methylamine Propargyl-PEG4-thiol Propargyl-PEG10-acid Propargyl-PEG2-methylamine Propargyl-PEG9-bromide Bromoacetamido-PEG4-Acid Propargyl-PEG8-bromide Benzyl-PEG5-Azide Bromoacetamido-PEG3-t-Butyl Ester Propargyl-PEG4-bromide Bromoacetamido-PEG3-Acid Bromo-PEG4-acid Propargyl-PEG3-NH2

  • Propargyl-PEG3-Bromide
  • Alkyne-PEG3-Br
  • PROPARGYL-PEG3-BR
  • 1-Propyne, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-
  • 3-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)prop-1-yne
  • Propargyl-PEG3-Br/1-Propyne, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-
  • 3- (2- (2- (2-bromoethoxy) ethoxy) ethoxy) propa-1-yne
  • 203740-63-0
  • peg