PF-06700841 tosylate

ChemicalBook > CAS DataBase List > PF-06700841 tosylate

Product Name: PF-06700841 tosylate
CAS No.: 1883299-62-4
Chemical Name: PF-06700841 tosylate
Synonyms: PF841;PF 841;PF-841;CS-2861;PF6700841;PF 6700841;PF-6700841;PF-06700841 tosylate;Brepocitinib (PF-06700841);inhibit,Janus kinase,PF06700841,JAK,Brepocitinib,Inhibitor,PF 06700841
CBNumber: CB94674167
Molecular Formula: C18H21F2N7O
Formula Weight: 389.4
MOL File: 1883299-62-4.mol

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PF-06700841 tosylate Property

Boiling point:: 637.1±65.0 °C(Predicted)
Density: 1.63±0.1 g/cm3(Predicted)
storage temp.: room temp
solubility: DMSO: 78 mg/mL (200.31 mM);Ethanol: 78 mg/mL (200.31 mM)
form: powder
pka: 7.28±0.10(Predicted)
color: white to beige
Water Solubility: Water: Insoluble

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PZ0345
Product name: PF-06700841 tosylate salt
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $114
Updated: 2024/03/01

Biorbyt Ltd

Product number: orb573132
Product name: PF-06700841 tosylate
Purity: >98%
Packaging: 100mg
Price: $1283.5
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573132
Product name: PF-06700841 tosylate
Purity: >98%
Packaging: 250mg
Price: $2245.7
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573132
Product name: PF-06700841 tosylate
Purity: >98%
Packaging: 1g
Price: $4766.8
Updated: 2021/12/16

DC Chemicals

Product number: DC12489
Product name: PF-06700841freebase
Purity: >98%
Packaging: 1g
Price: $3200
Updated: 2021/12/16

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PF-06700841 tosylate Chemical Properties,Usage,Production

Uses

PF-06700841 tosylate salt has been used as an inhibitor of Janus kinase1 (JAK1) to study its therapeutic effect on the adjuvant induced arthritis (AIA) rat model. It has also been used as an inhibitor of interferon-α/β receptor alpha chain (IFNAR1) signaling adaptor tyrosine kinase (2TYK2) in mice.

Biochem/physiol Actions

PF-06700841 prevents IL-23 (interleukin 23) signaling through TYK2 (Tyrosine-protein kinase 2)/JAK1 (Janus kinase 1) inhibition.

PF-06700841 tosylate Preparation Products And Raw materials

Raw materials

Preparation Products

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1883299-62-4, PF-06700841 tosylateRelated Search:

PF-6274484 PF-9366 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide 3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione PF-06447475 1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one Lorlatinib (PF-06463922) PF-06700841-TsOH PF-06282999 PF 4618433 PF-06650833 PF-6260933 5-PyriMidinecarboxaMide, 4-[(2-Methylpropyl)aMino]-N-(phenylMethyl)-2-[4-[(tetrahydro-2H-pyran-3-yl)Methyl]-1-piperazinyl]- PF-01247324 PNU 100480 PF 05175157 Ketohexokinase inhibitor 1 PF-562271

PF-06700841 tosylate

((S)-2,2-difluorocyclopropyl)(3-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone

PF 6700841

PF-06700841; PF 06700841; PF06700841; PF-6700841; PF 6700841; PF6700841; PF-06700841 TOSYLATE SALT

PF6700841

PF-6700841

CS-2861

((S)-2,2-difluorocyclopropyl)((1R,5S)-3-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone

Methanone, [(1S)-2,2-difluorocyclopropyl][3-[2-[(1-methyl-1H-pyrazol-4-yl)amino]-4-pyrimidinyl]-3,8-diazabicyclo[3.2.1]oct-8-yl]-

Brepocitinib (PF-06700841)

inhibit,Janus kinase,PF06700841,JAK,Brepocitinib,Inhibitor,PF 06700841

PF 841

PF841

PF-841

1883299-62-4

C18H21F2N7O

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