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Analytical Chemistry

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Analytical chemistry is the subject for the method and basic principle of studying and identifying of the composition, status, structure of matter as well as determination of related content. It is an important branch of chemistry subject. Analytical chemistry plays an important role in not only its own development but also in various fields related to the chemistry. We can say that all the practice of any human activity involving chemical phenomena is inseparable from analytical chemistry. Now, people have developed various kinds of different analytical methods, which can be classified based on an analysis task, analysis object, the basis of the analysis, requirement of the analysis and sample dosage.

According to the analysis tasks, it can be divided into qualitative analysis, quantitative analysis and structural analysis. Task of qualitative analysis is to identify the elements, radicals, functional groups or compounds that constituting the substances; the task of the quantitative analysis is to determine the content of the related components in the sample; the task of structural analysis is to study the molecular structure or crystal structure of the material.

(1) According to the analysis objects, it can be divided into organic and inorganic analysis; the object for the inorganic analysis is inorganic substance; the object of organic analysis is organic substance. In the inorganic analysis, it is generally required to determine what elements, ions, radicals or compounds that constitutes the sample and measure the percentage of each component; and sometimes it is also necessary for determination of the crystal structure; in the organic analysis, it not only requires the identification of the constituent elements, but also, more importantly, should do the structure analysis and functional group analysis.
(2) According to whether the analysis is based on the physical properties or chemical properties of the substance, it can be divided into instrumental analysis and chemical analysis. Depending on the specific requirements, it can be divided into routine analysis, rapid analysis and arbitration Analysis. Routine analysis refers to the general daily laboratory production analysis, also known as conventional analysis; rapid analysis is a kind of routine analysis and is mainly applied to the control of the production process, demanding the report of the results in the shortest possible time with the error generally being allowed to be greater; arbitration analysis is needed when there is controversy in the analysis results from different institute, demanding related department to conduct accurate analysis using specific method in order to determine the accuracy of the results of the original analysis.
(3) According to the amount of the sample, it can be generally divided into constant (> 0.1g), semi-micro (0.01 ~ 0.1g) and trace (1 ~ 10mg) analysis.
(4) In the inorganic qualitative chemical analysis, people generally apply semi-micro method while people generally apply constant analysis in the quantitative chemical analysis. According to the relative amounts of the analyzed components contained in the sample, it is also roughly divided into constant component analysis (> 1%), minor component analysis (0.01 to 1%) and trace components analysis (<0.01%). For the analysis of some trace amount of components contained in some kinds of complicated mixture and some substances, it is necessary to perform separation and enrichment. This produces a series of separation techniques, such as extraction, distillation, ion exchange, chromatography, sedimentation and flotation separation, these chemical separation techniques are an integral part of the analysis.

Environmental Analytical Chemistry
Environmental Analytical Chemistry is briefly referred to environmental analysis. It is a kind of subject to study the types, components of pollutants in the environment as well as how to perform qualitative and quantitative analysis on the chemical contaminants in the environment. It is a branch of environmental chemistry.

Environmental analytical chemistry emerged, developed and improved during the process of solving environmental problems. In 1950s, the public nuisance disease occurred in Japan had alerted the whole world. In order to find the cause of public nuisance disease, after experiencing as long as 11 years, later, the chemists of environmental analysis had applied light spectrum and identified that the river in Itai-itai disease area contained harmful elements such as lead, cadmium, arsenic and so on. Further by means of tracking element analysis of the soil and food in the disease area, people had found high lead and cadmium content. Later, people had further conducted spectral quantitative analysis on the body and bone of the patients in the disease area and found that the bone ashes contained alarmingly high content of zinc, lead and cadmium. To determine the causative agent, people further incorporated zinc, lead and cadmium into the food for feeding animals and conduct trace elemental analysis for animals and confirmed the serious harm of cadmium on the bone, revealing the cause of the Itai-itai disease. The development of modern science, especially the development of modern chemistry, physics, mathematics, electronics, biology, as well as the emergence of accurate, reliable, sensitive, selective, rapid, simple environmental pollution analysis technology and automation equipment, has been resulting in the maturation of environmental analytical chemistry. Environmental analytical chemistry now has penetrated into all areas of the entire environmental science subject. It is the most effective means of access to environmental information quality.
The objects of the environmental analytical chemistry research are quite complicated, including air, water, soil, sediment, minerals, waste, animals, plants, food, and human tissue. The content of chemical elements or compound to be determined in the environmental analytic chemistry is very low, with the absolute content being within the level of 10-6 to 10-12 grams.


The analysis technology in the environmental analytical chemistry is developing towards the direction of continuous automation, computerization and joint combination of various methods and instruments. Currently applied automatic analysis methods include colorimetric analysis, ion selective electrode, x-ray fluorescence spectroscopy, atomic absorption spectroscopy, polarography, gas chromatography, liquid chromatography and flow injection analysis. Laser, as the light source of analytical chemistry technique, has also been applied. Since the laser analysis has properties of high resolution, high sensitivity, long-range and short-term, the laser technology will play a pivotal role in the development of environmental analytical chemistry.

With the deepened development of environmental science, environmental analytical chemistry is often demanded for trace levels and ultra-trace-level detection and analysis, therefore, high sensitivity. Thus study of analysis methods of high sensitivity, good selectivity, rapid trace and ultra trace will become the major development direction for environmental analysis in the near future.

Qualitative Analysis of Chemistry
Qualitative analytic chemistry is the subject to identify the chemical elements and atoms groups contained in the sample. It is a branch subject of the analysis chemistry. Its purpose is to ascertain the chemical composition of the research object (specimen).
The major research content of the qualitative analytic chemistry includes:

1 the tested samples were analyzed separately. Namely take part of the sample and use exclusive reaction to detect a desire detection component.
2 systematic analysis of the samples. This means successively apply a few selective reactions for gradual separation of the ions followed by separation of each group until separating to only one substance and finally apply confirming reaction to ascertain the existence of this substance. The most famous cation system analysis method is H2S system. In recent years, due to the use of advanced equipment, qualitative analysis has also rapidly developed together with multivariate analysis and has also become an important direction for analytical chemistry.

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Structure:
Chemical Name:
Etonitazepyne
CAS:
2785346-75-8
MF:
C22H26N4O3
Chemical Name:
(1-carboxy-1-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)ethyl)-L-cysteine
Structure:
Chemical Name:
Pyrazinecarboxylic acid, 5-methyl-, 1-oxide (9CI)
CAS:
98502-96-6
MF:
C6H6N2O3
Structure:
Chemical Name:
1,4-Butanediaminium, N1,N4-diethyl-N1,N1,N4,N4-tetrakis(1-methylethyl)-, bromide (1:2)
CAS:
1621467-18-2
MF:
C20H46BrN2+
Structure:
Chemical Name:
1,6,10,14-Hexadecatetraen-3-ol, 3,7,11,15-tetramethyl-, (6Z,10E)-
CAS:
3790-76-9
MF:
C20H34O
Chemical Name:
Tafluprost Impurity 17
Chemical Name:
Rosuvastatin Impurity 160 (Sodium salt)
Structure:
Chemical Name:
Rosuvastatin Impurity 143
CAS:
2964549-48-0
MF:
C32H34F2N6O7S2
Chemical Name:
Rosuvastatin Impurity 131
Chemical Name:
Rosuvastatin Impurity 125
Chemical Name:
Metabotropic glutamate receptor 5 (GRM5) Antibody
Chemical Name:
Terlipressin Impurity 2 (des-Gly1,Gly2)
Structure:
Chemical Name:
BENZHYDRYL 6,6-DIHYDROPENICILLIC ACID 1-OXIDE[TAZOBACTAM INTERMEDIATE]
CAS:
87579-78-0
MF:
C21H21NO4S
Chemical Name:
4-(2-((2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)thiazol-4-yl)benzamide
Chemical Name:
Ertapenem Impurity C(USP)
Chemical Name:
Ertapenem Impurity 22
Structure:
Chemical Name:
4'-(Hydroxymethyl)-[1,1'-Biphenyl]-2-Carboxylic Acid
CAS:
158144-54-8
MF:
C14H12O3
Chemical Name:
Brivaracetam Impurity 118
Structure:
Chemical Name:
2-Thiazolidinethione, 3-acetyl- (9CI)
CAS:
76397-53-0
MF:
C5H7NOS2
Structure:
Chemical Name:
1-(4-((2-(4-hydroxypiperidin-1-yl)ethyl)(methyl)carbamoyl)benzyl)piperidine-4-carboxylic acid
CAS:
2975124-11-7
MF:
C22H34N4O3
Chemical Name:
Empagliflozin Impurity 108
Chemical Name:
Perospirone Impurity 28
Chemical Name:
Perospirone Impurity 23
Chemical Name:
Perospirone Impurity 16
Chemical Name:
Dolutegravir Impurity 24
Chemical Name:
Paxlovid Impurity 18
Chemical Name:
Related impurities of fluoxetine sodium 8
Chemical Name:
Fondaparinux sodium impurity 15
Chemical Name:
Fondaparinux Sodium Impurity 10
Chemical Name:
Oxacillin sodium Impurity E
Chemical Name:
ltrombopag Impurity 26
Chemical Name:
Revefenacin Impurity 19
Structure:
Chemical Name:
IBUPROFEN SODIUM SALT
CAS:
31121-93-4
MF:
C13H17NaO2
Structure:
Chemical Name:
5-Vinylpyrrolidone
CAS:
7529-16-0
MF:
C6H9NO
Structure:
Chemical Name:
1,3-BENZODIOXOLE-5,6-DIAMINE DIHYDROCHLORIDE
CAS:
81864-15-5
MF:
C7H10Cl2N2O2
Structure:
Chemical Name:
2-(1-METHYL-5-NITRO-1H-IMIDAZOL-2-YL)-PROPAN-2-OL
CAS:
35175-14-5
MF:
C7H11N3O3
Structure:
Chemical Name:
EPA
CAS:
73167-03-0
MF:
C20H29O2.Na
Structure:
Chemical Name:
10-METHYLUNDECANOIC ACID
CAS:
2724-56-3
MF:
C12H24O2
Structure:
Chemical Name:
2,3',4,5',6-PENTACHLOROBIPHENYL
CAS:
56558-18-0
MF:
C12H5Cl5
Structure:
Chemical Name:
OXY-CHLORDANE
CAS:
27304-13-8
MF:
C10H4Cl8O
Structure:
Chemical Name:
AMBERLITE(R) XAD-1180
CAS:
9003-69-4
MF:
C10H10
Structure:
Chemical Name:
3-HYDROXYHEXADECANOIC ACID
CAS:
928-17-6
MF:
C16H32O3
Structure:
Chemical Name:
4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID
CAS:
19741-14-1
MF:
C15H15N7O2
Structure:
Chemical Name:
TEPRALOXYDIM
CAS:
149979-41-9
MF:
C17H24ClNO4
Structure:
Chemical Name:
3-AMINO-2-OXAZOLIDINONE D4
CAS:
1188331-23-8
MF:
C3H2D4N2O2
Structure:
Chemical Name:
CYNARIN
CAS:
19870-46-3
MF:
C25H24O12
Structure:
Chemical Name:
DIETHYLTIN DICHLORIDE
CAS:
866-55-7
MF:
C4H10Cl2Sn
Structure:
Chemical Name:
Di-tert-butyl Chloromethyl Phosphate
CAS:
229625-50-7
MF:
C9H20ClO4P
Structure:
Chemical Name:
2-HYDROXYDODECANOIC ACID
CAS:
2984-55-6
MF:
C12H24O3
Structure:
Chemical Name:
2,3,4,5,6-Pentabromoethylbenzene
CAS:
85-22-3
MF:
C8H5Br5
Structure:
Chemical Name:
FLUORANTHENE-D10
CAS:
93951-69-0
MF:
C16D10
Structure:
Chemical Name:
2,2',3,3',4,5',6,6'-OCTACHLOROBIPHENYL
CAS:
40186-71-8
MF:
C12H2Cl8
Structure:
Chemical Name:
M-3-G HYDRATE
CAS:
20290-09-9
MF:
C23H27NO9
Structure:
Chemical Name:
PROPYLENE GLYCOL MONOLAURATE
CAS:
27194-74-7
MF:
C15H30O3
Structure:
Chemical Name:
Dibutyl butanephosphonate
CAS:
78-46-6
MF:
C12H27O3P
Structure:
Chemical Name:
CHLORBENSIDE
CAS:
103-17-3
MF:
C13H10Cl2S
Structure:
Chemical Name:
2,3,6-TRICHLOROANISOLE
CAS:
50375-10-5
MF:
C7H5Cl3O
Structure:
Chemical Name:
NIVALENOL
CAS:
23282-20-4
MF:
C15H20O7
Structure:
Chemical Name:
(S)-(+)-N-(3,5-DINITROBENZOYL)-ALPHA-PHENYLETHYLAMINE
CAS:
69632-31-1
MF:
C15H13N3O5
Structure:
Chemical Name:
INDENO(1,2,3-C,D)FLUORANTHENE
CAS:
193-43-1
MF:
C22H12
Structure:
Chemical Name:
2,2',3,3',4,4'-HEXACHLOROBIPHENYL
CAS:
38380-07-3
MF:
C12H4Cl6
Structure:
Chemical Name:
2,2',3,3',4,4',5,6,6'-NONACHLOROBIPHENYL
CAS:
52663-79-3
MF:
C12HCl9
Structure:
Chemical Name:
3,4,4'-TRICHLOROBIPHENYL
CAS:
38444-90-5
MF:
C12H7Cl3
Structure:
Chemical Name:
3-ACETYLDEOXYNIVALENOL
CAS:
50722-38-8
MF:
C17H22O7
Structure:
Chemical Name:
2,2',4,4',6,6'-HEXACHLOROBIPHENYL
CAS:
33979-03-2
MF:
C12H4Cl6
Structure:
Chemical Name:
4-BIPHENYLALDEHYDE OXIME
CAS:
40143-27-9
MF:
C13H11NO
Structure:
Chemical Name:
ZOPICLONE N-OXIDE
CAS:
43200-96-0
MF:
C17H17ClN6O4
Structure:
Chemical Name:
ALPHA-[BUTYLAMINO]METHYL-P-HYDROXYBENZYL ALCOHOL
CAS:
5716-20-1
MF:
C12H21NO6S
Structure:
Chemical Name:
OCTANOIC-D15 ACID
CAS:
69974-55-6
MF:
C8HD15O2
Structure:
Chemical Name:
ARACHIDONIC ACID SODIUM SALT
CAS:
6610-25-9
MF:
C20H31NaO2
Structure:
Chemical Name:
BROMOPYRAZONE
CAS:
3042-84-0
MF:
C10H8BrN3O
Structure:
Chemical Name:
PERYLENE-D12
CAS:
1520-96-3
MF:
C20H12
Structure:
Chemical Name:
DABSYL HYDRAZINE
CAS:
72565-41-4
MF:
C14H17N5O2S
Structure:
Chemical Name:
ETHYLENE DI(THIOTOSYLATE)
CAS:
2225-23-2
MF:
C16H18O4S4
Structure:
Chemical Name:
BENFLUOREX HYDROCHLORIDE
CAS:
23602-78-0
MF:
C19H20F3NO2
Structure:
Chemical Name:
ETHYL B-D-GLUCURONIDE
CAS:
17685-04-0
MF:
C8H14O7
Structure:
Chemical Name:
SALVINORIN A
CAS:
83729-01-5
MF:
C23H28O8
Structure:
Chemical Name:
(R)-(-)-NBD-APY
CAS:
143112-51-0
MF:
C10H11N5O3
Structure:
Chemical Name:
(-)-ALPHA-BISABOLOL
CAS:
22567-36-8
MF:
C15H26O2
Structure:
Chemical Name:
THIOMETON
CAS:
640-15-3
MF:
C6H15O2PS3
Structure:
Chemical Name:
7-(DIETHYLAMINO)COUMARIN-3-CARBOHYDRAZIDE
CAS:
100343-98-4
MF:
C14H17N3O3
Structure:
Chemical Name:
2,3,5,6-TETRACHLOROBIPHENYL
CAS:
33284-54-7
MF:
C12H6Cl4
Structure:
Chemical Name:
METHYL ARACHIDONATE
CAS:
2566-89-4
MF:
C21H34O2
Structure:
Chemical Name:
4-(N-NITROSOMETHYLAMINO)-1-(3-PYRIDYL)-1-BUTANONE
CAS:
64091-91-4
MF:
C10H13N3O2
Structure:
Chemical Name:
BISPHENOL A-D16
CAS:
96210-87-6
MF:
C15H16O2
Structure:
Chemical Name:
N-CHLOROMETHYL-4-NITROPHTHALIMIDE
CAS:
54455-34-4
MF:
C9H5ClN2O4
Structure:
Chemical Name:
NORFLUOXETINE HYDROCHLORIDE
CAS:
57226-68-3
MF:
C16H17ClF3NO
Structure:
Chemical Name:
2,2',4,5'-TETRACHLOROBIPHENYL
CAS:
41464-40-8
MF:
C12H6Cl4
Structure:
Chemical Name:
2,3'-DICHLOROBIPHENYL
CAS:
25569-80-6
MF:
C12H8Cl2
Structure:
Chemical Name:
CUMYLURON
CAS:
99485-76-4
MF:
C17H19ClN2O
Structure:
Chemical Name:
DALAPON-METHYL ESTER
CAS:
17640-02-7
MF:
C4H6Cl2O2
Structure:
Chemical Name:
Atorvastatin hemicalcium trihydrate
CAS:
344423-98-9
MF:
C66H74CaF2N4O13
Structure:
Chemical Name:
PROTHOATE
CAS:
2275-18-5
MF:
C9H20NO3PS2
Structure:
Chemical Name:
2-Ethylhexyl 2-(2,4-dichlorophenoxy)propionate
CAS:
79270-78-3
MF:
C17H24Cl2O3
Structure:
Chemical Name:
HEXADECANOIC ACID-1-13C
CAS:
57677-53-9
MF:
C16H32O2
Structure:
Chemical Name:
DBD-ED
CAS:
189373-41-9
MF:
C10H15N5O3S
Structure:
Chemical Name:
ENDOSULFAN ETHER
CAS:
3369-52-6
MF:
C9H6Cl6O
Structure:
Chemical Name:
2,2',3,3',4,4',5,5',6-NONACHLOROBIPHENYL
CAS:
40186-72-9
MF:
C12HCl9
Chemical Name:
TWEEN 85
CAS:
9055-70-3
MF:
C60H108O8.(C2H4O)n
Structure:
Chemical Name:
2-(Methylamino)-1-(4-methylphenyl)-1-propanone hydrochloride
CAS:
1189726-22-4
MF:
C11H15NO.HCl