ChemicalBook > CAS DataBase List > Ammonium formate

Ammonium formate

Product Name
Ammonium formate
CAS No.
540-69-2
Chemical Name
Ammonium formate
Synonyms
AMMONIUM FORMAT;AMMONIUM FORMIATE;Ammomium formate;HCOONH4 CH5NO2;mravencanamonny;97.0%， for HPLC;Formiate ammonia;AMMONIUM FORMATE;ammmonium formate;formated’ammonium
CBNumber
CB3140017
Molecular Formula
CH5NO2
Formula Weight
63.06
MOL File
540-69-2.mol
More
Less

Ammonium formate Property

Melting point:
119-121 °C (lit.)
Boiling point:
103.28°C (rough estimate)
Density 
1.26 g/mL at 25 °C (lit.)
vapor pressure 
0.033Pa at 25℃
refractive index 
1.4164 (estimate)
Flash point:
104℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: 10 M at 20 °C, clear, colorless
form 
Solid
color 
White
Odor
Slight formic acid odour
PH Range
6 - 7
PH
6.53(1 mM solution);6.5(10 mM solution);6.49(100 mM solution);6.45(1000 mM solution)
Water Solubility 
soluble
Sensitive 
Hygroscopic
λmax
λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.04
Merck 
14,523
BRN 
3625095
Stability:
Stable. Hygroscopic. Incompatible with strong acids, strong oxidizing agents.
InChIKey
VZTDIZULWFCMLS-UHFFFAOYSA-N
LogP
-3.34 at 25℃
CAS DataBase Reference
540-69-2(CAS DataBase Reference)
EPA Substance Registry System
Ammonium formate (540-69-2)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
2
RTECS 
BQ6650000
F 
3-10
TSCA 
Yes
HS Code 
29151200
Hazardous Substances Data
540-69-2(Hazardous Substances Data)
Toxicity
LD50 orl-mus: 2250 mg/kg ZERNAL 9,332,69
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
78314
Product name
Ammonium formate solution
Purity
BioUltra, 10?M in H2O
Packaging
100mL
Price
$107
Updated
2024/03/01
Sigma-Aldrich
Product number
78314
Product name
Ammonium formate solution
Purity
BioUltra, 10?M in H2O
Packaging
500mL
Price
$373
Updated
2024/03/01
Sigma-Aldrich
Product number
70221
Product name
Ammonium formate
Purity
eluent additive for LC-MS, LiChropur?, ≥99.0%
Packaging
25g
Price
$170
Updated
2024/03/01
Sigma-Aldrich
Product number
70221
Product name
Ammonium formate
Purity
eluent additive for LC-MS, LiChropur?, ≥99.0%
Packaging
100g
Price
$617
Updated
2024/03/01
Sigma-Aldrich
Product number
156264
Product name
Ammonium formate
Purity
reagent grade, 97%
Packaging
1kg
Price
$144
Updated
2024/03/01
More
Less

Ammonium formate Chemical Properties,Usage,Production

Chemical Properties

Ammonium formate, NH4HCO2, is the ammonium salt of formic acid. It is a colorless, hygroscopic, crystalline solid. It can be synthesized through treating ammonium carbonate with 85% formic acid. It is widely used in many organic reactions such as Leuckart reaction which is the reductive amination of aldehydes and ketones. It can also be used as a buffer in HPLC and LC/MS test. Moreover, it is also used in palladium on carbon (Pd/C) reduction of functional group. It can also be used for the preparation of formic acid in situ as well as being used to store formic acid.

Common HPLC Buffers: Ammonium formate (2.7<PH<3.7) does a fairly good job of filling the gap at the low-pH end.

Physical properties

White monoclinic deliquescent crystals or granules; density 1.280 g/cm3; melts at 116°C; highly soluble in water (102 g/100 g at 0°C), solubility rapidly increasing with temperature (i.e., 531 g/100 g at 80°C); soluble in liquid ammonia, alcohol and ether.

Uses

Ammonium formate is widely used in various organic reactions like Leuckart reaction which involves the reductive amination of aldehydes and ketones. It serves as a buffer in high performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC/MS). It finds application in palladium on carbon (Pd/C) reduction of functional groups. For example, reduction of alkenes to alkanes and formaldehyde to methanol. It is also used to prepare formic acid insitu as well as used to store formic acid by making it as an ammonium salt.

Uses

Pure ammonium formate decomposes into formamide and water when heated, and this is its primary use in industry. Formic acid can also be obtained by reacting ammonium formate with a dilute acid, and since ammonium formate is also produced from formic acid, it can serve as a way of storing formic acid.
In chemical analysis, especially to ppt base metals from salts of the "noble" metals. Ammonium formate can also be used in palladium on carbon (Pd / C) reduction of functional groups. In the presence of Pd / C, ammonium formate decomposes to hydrogen, carbon dioxide, and ammonia.
Ammonium formate can be used for reductive amination of aldehydes and ketones (Leuckart reaction)
Ammonium formate can be used as a buffer in high performance liquid chromatography (HPLC), and is suitable for use with liquid chromatography/mass spectrometry (LC/MS). .

Definition

ChEBI: Ammonium formate is the ammonium salt of formic acid. It has a role as a buffer. It is functionally related to a formic acid.

Reactions

When heated, ammonium formate eliminates water, forming formamide. Upon further heating it forms to HCN and H2O. A side reaction of this is the decomposition of formamide to CO and NH3.

Air & Water Reactions

Ammonium formate is generally soluble in water. 

Reactivity Profile

Salts, basic, such as Ammonium formate, are generally soluble in water. The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0. They react as bases to neutralize acids. These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

Health Hazard

Inhalation causes irritation of nose and throat. Ingestion irritates mouth and stomach. Contact with eyes or skin causes irritation.

Fire Hazard

Special Hazards of Combustion Products: Toxic and irritating ammonia and formic acid gases may form in fire.

Safety Profile

Moderately toxic by ingestion andintravenous routes. When heated to decomposition itemits toxic fumes of NOx and NH3.

Purification Methods

Heat the solid in NH3 vapour and dry it in a vacuum till the NH3 odour is faint (note that it can evaporate completely in a vacuum). Recrystallise it from absolute EtOH and then keep it in a desiccator over 99% H2SO4 in vacuo. It is very hygroscopic. It exists in two forms, stable needles and less stable plates. It also forms acid salts, i.e. HCO2NH4.3HCO2H and HCO2NH4.HCO2H. [Kensall & Adler J Am Chem Soc 43 1473 1921, Beilstein 2 IV 18.]

References

[1] http://www.orgsyn.org/demo.aspx?prep=CV2P0503
[2] https://www.alfa.com/zh-cn/catalog/014517/
[3] https://en.wikipedia.org/wiki/Ammonium_formate
[4] GAO X, MA Y, ZHOU F, et al. Promotion Mechanism of Ammonium Formate in Ammonium Salt Leaching Process for Weathered Crust Elution-Deposited Rare Earth Ores[J]. Minerals, 2023, 1 1: 0. DOI:10.3390/min13101286.
[5] A. S. KORNILOV. Uranium Stripping with Ammonium Acetate and Formate[J]. Radiochemistry, 2024, 65 1 supplement: S172-S176. DOI:10.1134/S1066362223070159.
[6] ISHANI BORTHAKUR, SABUJ KUNDU* Reductive Aminomethylation Using Ammonium Formate and Methanol as N1 and C1 Source: Direct Synthesis of Mono- and Di-Methylated Amines[J]. ACS Catalysis , 2024, 14 8: 5847-5857. DOI:10.1021/acscatal.4c00346.

Ammonium formate Preparation Products And Raw materials

Raw materials

4-Chlorobenzaldehyde Formic acid Ammonia

Preparation Products

3-Azetidinecarboxylic acid 4-(Trifluoromethyl)nicotinic acid (R)-(-)-2-AMINOHEPTANE 5-Fluoro-2-picolinic acid (1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)METHYLAMINE 1-N-Boc-3-hydroxyazetidine C-(1-METHYL-PIPERIDIN-2-YL)-METHYLAMINE 4-METHYL-1,3-OXAZOLE-5-CARBOXYLIC ACID 1,2,4-Triazole Citrazinic acid 4-METHYLOXAZOLE-5-CARBONYL CHLORIDE 3,4,5-Trimethoxybenzylamine 5-(AMINOMETHYL)-2,3-DIHYDROBENZO[B]FURAN 4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE Teicoplanin A2 3-Chlorobenzylamine DL-alpha-Methylbenzylamine 4-Aminotetrahydropyran 5-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID 4-CHLORO-2-METHYLBENZYLAMINE 7-Methylthieno[3,2-d]pyrimidin-4(3H)-one (4S)-HYDROXY-3-METHYL-2-(2-PROPENYL)-2-CYCLOPENTENE-1-ONE 3-(4-Morpholinyl)aniline 5-amino-1H-Indole-2-carboxylic acid ethyl ester 5-Azaindole (1H-INDAZOL-3-YL)-ACETIC ACID 4-Hydroxy-3-methoxybenzylamine hydrochloride 3-Amino-5-fluoropyridine DL-ALPHA-METHYLBENZYLAMINE Triadimefon ETHYL 5-AMINO-1H-INDOLE-2-CARBOXYLATE 3,5-Bis(trifluoromethyl)benzylamine 3-Amino-4-methoxybenzoic acid 2,5-Dimethoxybenzylamine
More
Less

Ammonium formate Suppliers

Belgium 1 Canada 1 China 406 Europe 3 France 2 Germany 1 India 55 Japan 5 Switzerland 1 United Kingdom 8 United States 51 USA 1 Global 535
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Jiangsu Kolod Food Ingredients Co.,Ltd.
Tel
0518-85110930 18861332078
Fax
0518-85115307
Email
office2079@jskolod.com
Country
China
ProdList
35
Advantage
58
Lianyungang Kexin Chemical Co., Ltd.
Tel
518-518-+86-188051 +86-18805133257
Fax
051885110578
Email
sales3257@jskolod.com
Country
China
ProdList
100
Advantage
58
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2866
Advantage
58
Shanghai hongrui chemical co., ltd
Tel
13906273813 13485185589
Email
834955168@qq.com
Country
China
ProdList
35
Advantage
58
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
020-36607679 17825480238
Fax
QQ 3008233717
Email
3008233746@qq.com
Country
China
ProdList
9919
Advantage
12
Wuhan Chuangshuo Chemical Technology Co., Ltd
Tel
027-17773669204 17773669204
Email
3807504233@qq.com
Country
China
ProdList
298
Advantage
58
Tianjin Zhongxin Chemtech Co., Ltd.
Tel
022-66880623
Fax
86(0)22-66880086
Email
sales@tjzxchem.com
Country
China
ProdList
613
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
shanghai science Bio-Pharmceutical.co,ltd.
Tel
021-021-57872719 13761402923
Fax
02157872719
Email
245662540@qq.com
Country
China
ProdList
309
Advantage
60
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19179
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
DKD Shijiazhuang Chemical Co., Ltd.
Tel
0311-0311-67790228 15531158659
Fax
66571013
Email
1257738041@qq.com
Country
China
ProdList
153
Advantage
62
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4554
Advantage
62
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Jinan Bond Chemical Technology Co., Ltd.
Tel
86-531-88280989
Fax
86-531-88280989
Email
mymail1996@126.com
Country
China
ProdList
256
Advantage
55
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9458
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Simagchem Corp.
Tel
86 592 2680277
Fax
0086 592 2680237
Email
sale@simagchem.com
Country
China
ProdList
430
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3930
Advantage
58
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3583
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
RiZhao LiDeShi Chemical Co., Ltd.
Tel
010-51268198
Fax
010-63833209
Email
leadershipchem@126.com
Country
China
ProdList
2546
Advantage
58
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
0371-13526885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
Country
China
ProdList
3978
Advantage
58
Mei Lan Industrial (Shanghai) Co., Ltd.
Tel
021-58958189
Fax
021-58957967
Email
wouchina@126.com
Country
China
ProdList
2666
Advantage
55
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9346
Advantage
58
More
Less

View Lastest Price from Ammonium formate manufacturers

Dorne Chemical Technology co. LTD
Product
Ammonium formate 540-69-2
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1000kg
Release date
2024-03-26
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Ammonium Formate 540-69-2
Price
US $65.00-20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-31
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ammonium formate 540-69-2
Price
US $0.00/Kg/Bag
Min. Order
25KG
Purity
98%min
Supply Ability
20 TONS
Release date
2021-06-21

540-69-2, Ammonium formateRelated Search:

Ammonium benzoate Ammonium chloride Ammonium hydroxide Ammonium acetate Ammonium sulfate Nalpha-Cbz-L-Arginine BENZYL CYANOFORMATE METHYL ISOCYANOACETATE Ethyl cyanoformate Ethyl isocyanoacetate Alizarin Complexone DCU 1-Amino-1-cyclohexanecarboxylic acid Tranexamic Acid 4-CYANOPHENYL 4-N-BUTYLBENZOATE 4-CYANOPHENYL 4-HEPTYLBENZOATE Cycloleucine Methyl 4-cyanobenzoate

  • AMMONIUM FORMATE SOLUTION
  • AMMONIUM FORMATE
  • AMMONIUM FORMIATE
  • FORMIC ACID, AMMONIUM
  • FORMIC ACID AMMONIUM SALT
  • AMMONIUMFORMATE,CRYSTAL,REAGENT
  • Ammonium formate, 97%, water <3%
  • Formiate ammonia
  • AMMONIUM FORMATE extrapure AR
  • Ammonium formiate/97+%
  • AMMONIUM FORMATE SOLUTION COMMERCIAL
  • AMMoniuM forMate, 97% 1KG
  • AMMoniuM forMate, 99% 1KG
  • AMMoniuM forMate, 99% 250GR
  • AMMoniuM forMate anhydrous
  • aMMoniuM forMate NH4O2CH, high pressure
  • ForMicacid, aMMoniuM salt (1:1)
  • AMMoniuM forMate >=99.995% trace Metals basis
  • Ammonium formate reagent grade, 97%
  • Ammonium formate Vetec(TM) reagent grade, >=96%
  • ammmonium formate
  • Формиат аммония, Ammonium formate, Formic acid ammonium salt
  • HCOONH4 CH5NO2
  • AMMONIUM FORMATE, REAGENTAMMONIUM FORMATE, REAGENTAMMONIUM FORMATE, REAGENTAMMONIUM FORMATE, REAGENT
  • formated’ammonium
  • mravencanamonny
  • Ammonium formate, Eluent additive for LC-MS
  • AMMONIUM FORMATE, 99.995+% METALS BASIS
  • AMMONIUM FORMATE REAGENT GRADE 97%
  • AMMONIUM FORMATE SOLUTION 10M
  • AMMONIUM FORMATE PURE
  • AmmoniumFormateAr
  • AmmoniumFormateReagent
  • AmmoniumFormateGr
  • Ammoniumformate,99%
  • Ammoniumformate,97%
  • AMMONIUM FORMAT
  • AMMONIUM FORMATE SOLUTION, 10 MM IN H2O&
  • Ammonium formate,anhydrous, free-flowing
  • Ammonium formate≥ 98% (Titration)
  • Ammonium formate, Water <3%
  • Ammomium formate
  • 1mol/l Ammonium Formate Solution
  • Ammonium formate ISO 9001：2015 REACH
  • Factory Supply CAS 540-69-2 Ammonium Formate
  • Ammonium formate, GR 97%+
  • Ammonium formate extrapure 500GM
  • Ammonium formate ULC-MS
  • Ammonium Formate extrapure AR, ExiPlus, Multi-Compendial, 98%
  • Ammonium Formate (SQ), Qualigens
  • Ammonium formate, extra pure, SLR 500GR
  • Ammonium formate, for analysis 500GR
  • AMMONIUM FORMATE Extra Pure
  • 97.0%， for HPLC
  • Ammonium formate，for UPLC/LC-MS
  • 4-Iodoanisammonium formate
  • Ammonium formate (6CI)
  • AMMONIUM FO ROMATE