Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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Organic reagents

Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.

After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.

8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.

Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.

Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.

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Structure:
Chemical Name:
ACRYLIC ACID TETRADECYL ESTER
CAS:
21643-42-5
MF:
C17H32O2
Structure:
Chemical Name:
SULPROFOS-SULFOXIDE
CAS:
34643-47-5
MF:
C12H19O3PS3
Structure:
Chemical Name:
1,7-DIOXASPIRO[5.5]UNDECANE
CAS:
180-84-7
MF:
C9H16O2
Chemical Name:
AZIDE DEXTROSE BROTH
Structure:
Chemical Name:
DIETHYL TRANS-1,2-CYCLOPROPANEDICARBOXYLATE
CAS:
3999-55-1
MF:
C9H14O4
Structure:
Chemical Name:
1,2-Epoxy-4-vinylcyclohexane
CAS:
106-86-5
MF:
C8H12O
Structure:
Chemical Name:
6,6-DIMETHYLFULVENE
CAS:
2175-91-9
MF:
C8H10
Structure:
Chemical Name:
2-AMINO-3,5-DIIODOBENZOIC ACID
CAS:
609-86-9
MF:
C7H5I2NO2
Structure:
Chemical Name:
Triphenylformazan
CAS:
531-52-2
MF:
C19H16N4
Structure:
Chemical Name:
BENZYLTRIMETHYLSILANE
CAS:
770-09-2
MF:
C10H16Si
Structure:
Chemical Name:
Coumarin-3-carboxylic acid
CAS:
531-81-7
MF:
C10H6O4
Structure:
Chemical Name:
PENTAFLUOROPHENYLETHOXYDIMETHYLSILANE
CAS:
71338-73-3
MF:
C10H11F5OSi
Structure:
Chemical Name:
2,5-Hexanediol
CAS:
2935-44-6
MF:
C6H14O2
Structure:
Chemical Name:
4-CHLORO-3,5-DINITROBENZONITRILE
CAS:
1930-72-9
MF:
C7H2ClN3O4
Structure:
Chemical Name:
Methyl 3-chlorobenzoate
CAS:
2905-65-9
MF:
C8H7ClO2
Structure:
Chemical Name:
(1R)-(-)-10-CAMPHORSULFONIC ACID, AMMONIUM SALT
CAS:
82509-30-6
MF:
C10H19NO4S
Structure:
Chemical Name:
1,1'-DIETHYL-4,4'-CARBOCYANINE IODIDE
CAS:
4727-50-8
MF:
C25H25IN2
Structure:
Chemical Name:
9-ETHYL-3-[N-ETHYL-N-(O-TOLYL)HYDRAZONOMETHYL]CARBAZOLE
CAS:
1274948-12-7
MF:
C24H25N3
Structure:
Chemical Name:
4-ETHYLPHENYL ISOTHIOCYANATE
CAS:
18856-63-8
MF:
C9H9NS
Structure:
Chemical Name:
2-CHLOROETHANESULFONIC ACID SODIUM SALT MONOHYDRATE
MF:
C2H6ClNaO4S
Structure:
Chemical Name:
4-BENZYLOXYPROPIOPHENONE
CAS:
4495-66-3
MF:
C16H16O2
Structure:
Chemical Name:
1-PHENYLUNDECANE
CAS:
6742-54-7
MF:
C17H28
Structure:
Chemical Name:
3-PHENOXYPHENYLACETIC ACID
CAS:
32852-81-6
MF:
C14H12O3
Structure:
Chemical Name:
3-TERT-BUTYL-2-HYDROXYBENZALDEHYDE
CAS:
24623-65-2
MF:
C11H14O2
Structure:
Chemical Name:
4-Methoxybiphenyl
CAS:
613-37-6
MF:
C13H12O
Structure:
Chemical Name:
3-(TRIFLUOROMETHYL)PHENYLTRIMETHYLAMMONIUM HYDROXIDE
CAS:
68254-41-1
MF:
C10H14F3NO
Structure:
Chemical Name:
2-Amino-1-(4-chlorophenyl)propan-1-ol
CAS:
57908-21-1
MF:
C9H12ClNO
Structure:
Chemical Name:
TERBUFOS-SULFOXIDE
CAS:
10548-10-4
MF:
C9H21O3PS3
Structure:
Chemical Name:
4-PIPERAZIN-1-YL-BENZOIC ACID
CAS:
85474-75-5
MF:
C11H14N2O2
Structure:
Chemical Name:
8-METHYL-8-AZABICYCLO[3.2.1]OCTAN-3-OL HYDROCHLORIDE
CAS:
258345-27-6
MF:
C8H16ClNO
Structure:
Chemical Name:
2-ISOPROPYLANISOLE
CAS:
2944-47-0
MF:
C10H14O
Structure:
Chemical Name:
3,9-DODECADIYNE
CAS:
61827-89-2
MF:
C12H18
Structure:
Chemical Name:
3',5'-Difluoropropiophenone
CAS:
135306-45-5
MF:
C9H8F2O
Structure:
Chemical Name:
2,3-DIMETHYLNAPHTHALENE
CAS:
581-40-8
MF:
C12H12
Structure:
Chemical Name:
3-METHYLCHOLANTHRENE
CAS:
56-49-5
MF:
C21H16
Structure:
Chemical Name:
5-Hexenenitrile
CAS:
5048-19-1
MF:
C6H9N
Structure:
Chemical Name:
D-Glyceraldehyde
CAS:
453-17-8
MF:
C3H6O3
Structure:
Chemical Name:
METHYLSULFAMIC ACID
CAS:
4112-03-2
MF:
CH5NO3S
Structure:
Chemical Name:
3-(METHYLTHIO)PHENYL ISOTHIOCYANATE
CAS:
51333-80-3
MF:
C8H7NS2
Structure:
Chemical Name:
2-Oxopentanoic acid
CAS:
1821-02-9
MF:
C5H8O3
Structure:
Chemical Name:
4-CHLORO-3-NITROBENZOPHENONE
CAS:
56107-02-9
MF:
C13H8ClNO3
Structure:
Chemical Name:
2,4,5-TRICHLOROTHIOPHENOL
CAS:
3773-14-6
MF:
C6H3Cl3S
Structure:
Chemical Name:
6-CHLOROPIPERONYL CHLORIDE
CAS:
23468-31-7
MF:
C8H6Cl2O2
Structure:
Chemical Name:
N-ISOPROPYLHYDROXYLAMINE HYDROCHLORIDE
CAS:
50632-53-6
MF:
C3H10ClNO
Structure:
Chemical Name:
N-HEPTACOSANE
CAS:
593-49-7
MF:
C27H56
Structure:
Chemical Name:
N-Acetylanthranilic acid
CAS:
89-52-1
MF:
C9H9NO3
Structure:
Chemical Name:
2,3,4,5,6-PENTABROMOBENZYL ALCOHOL
CAS:
79415-41-1
MF:
C7H3Br5O
Structure:
Chemical Name:
2-(2,4,5-TRICHLOROPHENOXY)PROPIONIC ACID
CAS:
93-72-1
MF:
C9H7Cl3O3
Structure:
Chemical Name:
9-CYANOPHENANTHRENE
CAS:
2510-55-6
MF:
C15H9N
Structure:
Chemical Name:
Methyl 2-oxocyclohexanecarboxylate
CAS:
41302-34-5
MF:
C8H12O3
Structure:
Chemical Name:
4'-AMINOPROPIOPHENONE
CAS:
70-69-9
MF:
C9H11NO
Structure:
Chemical Name:
Phenylsuccinic anhydride
CAS:
1131-15-3
MF:
C10H8O3
Structure:
Chemical Name:
2,5-DIMETHYLBENZONITRILE
CAS:
13730-09-1
MF:
C9H9N
Structure:
Chemical Name:
METHIOCARB SULFOXIDE
CAS:
2635-10-1
MF:
C11H15NO3S
Structure:
Chemical Name:
4-AZIDOANILINE HYDROCHLORIDE
CAS:
91159-79-4
MF:
C6H7ClN4
Structure:
Chemical Name:
2-Chlorobutyric acid
CAS:
4170-24-5
MF:
C4H7ClO2
Structure:
Chemical Name:
1-amino-4-methyl-1H-imidazole-2-thiol
CAS:
16163-48-7
MF:
C4H7N3S
Structure:
Chemical Name:
4-(Morpholinomethyl)phenylboronic acid
CAS:
279262-23-6
MF:
C11H16BNO3
Structure:
Chemical Name:
4,4'-DIFORMYLTRIPHENYLAMINE
CAS:
53566-95-3
MF:
C20H15NO2
Structure:
Chemical Name:
PYRIDINE-3-BORONIC ACID 1,3-PROPANEDIOL CYCLIC ESTER
CAS:
131534-65-1
MF:
C8H10BNO2
Structure:
Chemical Name:
1-(2-Chlorophenyl)acetone
CAS:
6305-95-9
MF:
C9H9ClO
Structure:
Chemical Name:
FENTHION-OXON-SULFOXIDE
CAS:
6552-13-2
MF:
C10H15O5PS
Structure:
Chemical Name:
DL-BETA-PHENYLLACTIC ACID
CAS:
828-01-3
MF:
C9H10O3
Structure:
Chemical Name:
TRIPHENYLBORANE
CAS:
960-71-4
MF:
C18H15B
Structure:
Chemical Name:
(METHYLTHIO)ACETIC ACID
CAS:
2444-37-3
MF:
C3H6O2S
Structure:
Chemical Name:
N,N-DIETHYL-GUANIDINE
CAS:
18240-93-2
MF:
C5H13N3
Structure:
Chemical Name:
2,3-ANTHRACENEDICARBOXYLIC ANHYDRIDE
CAS:
6812-14-2
MF:
C16H8O3
Structure:
Chemical Name:
4-(Methylsulfonyl)phenylhydrazine hydrochloride
CAS:
17852-67-4
MF:
C7H11ClN2O2S
Structure:
Chemical Name:
MELLITIC ACID
CAS:
517-60-2
MF:
C12H6O12
Structure:
Chemical Name:
SODIUM HYDROSULFIDE HYDRATE
CAS:
207683-19-0
MF:
H3NaOS
Structure:
Chemical Name:
SEC-BUTYL METHYL ETHER
CAS:
6795-87-5
MF:
C5H12O
Structure:
Chemical Name:
2,4-DIMETHOXYPHENYL ISOTHIOCYANATE
CAS:
33904-03-9
MF:
C9H9NO2S
Structure:
Chemical Name:
(3-Phenylaminocarbonylphenyl)boronic acid
CAS:
397843-71-9
MF:
C13H12BNO3
Structure:
Chemical Name:
4-Chlorobenzylsulfonyl chloride
CAS:
6966-45-6
MF:
C7H6Cl2O2S
Structure:
Chemical Name:
1,1,3-TRIMETHOXYPROPANE
CAS:
14315-97-0
MF:
C6H14O3
Structure:
Chemical Name:
CYCLOPROPANESULFINIC ACID, SODIUM SALT
CAS:
910209-21-1
MF:
C3H7NaO2S
Structure:
Chemical Name:
TRICHLOROMETHYL ISOCYANATE
CAS:
30121-98-3
MF:
C2Cl3NO
Structure:
Chemical Name:
4-METHOXYBENZENEDIAZONIUM TETRAFLUOROBORATE
CAS:
459-64-3
MF:
C7H7BF4N2O
Structure:
Chemical Name:
4-PENTYN-2-OL
CAS:
2117-11-5
MF:
C5H8O
Structure:
Chemical Name:
TOLUENE-4-SULFINIC ACID LITHIUM SALT
CAS:
16844-27-2
MF:
C7H7LiO2S
Structure:
Chemical Name:
TETRAHEPTYLAMMONIUM IODIDE
CAS:
3535-83-9
MF:
C28H60IN
Structure:
Chemical Name:
4-AMINO-5-PHENYL-4H-1,2,4-TRIAZOLE-3-THIOL
CAS:
21089-45-2
MF:
C8H8N4S
Structure:
Chemical Name:
5-FLUOROBENZO[D]OXAZOLE-2-THIOL
CAS:
13451-78-0
MF:
C7H4FNOS
Structure:
Chemical Name:
3-METHOXYBIPHENYL
CAS:
2113-56-6
MF:
C13H12O
Structure:
Chemical Name:
2-BROMO-2'-METHOXYACETOPHENONE
CAS:
31949-21-0
MF:
C9H9BrO2
Structure:
Chemical Name:
SUCCINAMIC ACID
CAS:
638-32-4
MF:
C4H7NO3
Structure:
Chemical Name:
CIS-ACONITIC ACID
CAS:
585-84-2
MF:
C6H6O6
Structure:
Chemical Name:
4-SULFOPHTHALIC ACID
CAS:
89-08-7
MF:
C8H6O7S
Structure:
Chemical Name:
2-CHLORO-6-FLUORO-3-METHYLBENZALDEHYDE
CAS:
104451-99-2
MF:
C8H6ClFO
Structure:
Chemical Name:
3-METHYLPHENOXYACETIC ACID
CAS:
1643-15-8
MF:
C9H10O3
Structure:
Chemical Name:
2,2'-DITHIODIETHANOL
CAS:
1892-29-1
MF:
C4H10O2S2
Structure:
Chemical Name:
,5-Dihydro-5-methyl-6-[4-(4-oxo-1(4H)-pyridinyl)phenyl]-1,2,4-triazin-3(2H)-one
CAS:
113118-31-3
MF:
C15H14N4O2
Structure:
Chemical Name:
8-Anilino-1-naphthalenesulfonic acid ammonium salt
CAS:
28836-03-5
MF:
C16H16N2O3S
Structure:
Chemical Name:
(S)-(-)-METHYL P-TOLYL SULFOXIDE
CAS:
5056-07-5
MF:
C8H10OS
Structure:
Chemical Name:
Resorcinol sulfide
CAS:
97-29-0
MF:
C12H10O4S
Structure:
Chemical Name:
2,4,6-Trimethylbenzylamine
CAS:
40393-99-5
MF:
C10H15N
Structure:
Chemical Name:
BIUREA
CAS:
110-21-4
MF:
C2H6N4O2
Structure:
Chemical Name:
4-Isopropylbiphenyl
CAS:
7116-95-2
MF:
C15H16
Structure:
Chemical Name:
TRANS-2-METHYLCYCLOHEXANOL
CAS:
7443-52-9
MF:
C7H14O
Structure:
Chemical Name:
N-PENTADECANOIC ACID ETHYL ESTER
CAS:
41114-00-5
MF:
C17H34O2