Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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Organic reagents

Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.

After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.

8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.

Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.

Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.

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Structure:
Chemical Name:
(3,4-Diaminophenyl)phenylmethanone
CAS:
39070-63-8
MF:
C13H12N2O
Structure:
Chemical Name:
3-Hexyn-2,5-diol
CAS:
3031-66-1
MF:
C6H10O2
Structure:
Chemical Name:
Disodium 2-naphthol-3,7-disulfonate
CAS:
83949-45-5
MF:
C10H9NaO7S2
Structure:
Chemical Name:
GLUTARYL DICHLORIDE
CAS:
2873-74-7
MF:
C5H6Cl2O2
Structure:
Chemical Name:
N-HEPTYLBENZENE
CAS:
1078-71-3
MF:
C13H20
Structure:
Chemical Name:
4-Amino-3-nitrobenzophenone
CAS:
31431-19-3
MF:
C13H10N2O3
Structure:
Chemical Name:
N-DODECYLTRIETHOXYSILANE
CAS:
18536-91-9
MF:
C18H40O3Si
Structure:
Chemical Name:
3-METHOXY THIOANISOLE
CAS:
2388-74-1
MF:
C8H10OS
Structure:
Chemical Name:
3-(METHYLTHIO)PROPYLAMINE
CAS:
4104-45-4
MF:
C4H11NS
Structure:
Chemical Name:
1-Ethyl-3-methylimidazolium hexafluorophosphate
CAS:
155371-19-0
MF:
C6H11F6N2P
Structure:
Chemical Name:
1,4-Bis(aminomethyl)benzene
CAS:
539-48-0
MF:
C8H12N2
Structure:
Chemical Name:
ETHYL PHENYLPROPIOLATE
CAS:
2216-94-6
MF:
C11H10O2
Structure:
Chemical Name:
5-(PROPYLTHIO)-1,3,4-THIADIAZOLE-2-THIOL
CAS:
19921-88-1
MF:
C5H8N2S3
Structure:
Chemical Name:
2-METHYL-2-PENTANOL
CAS:
590-36-3
MF:
C6H14O
Structure:
Chemical Name:
3-CHLORO-4-FORMYLPHENYLBORONIC ACID
CAS:
1072952-53-4
MF:
C7H6BClO3
Structure:
Chemical Name:
4-BENZYLOXY-3-METHOXYBENZALDEHYDE
CAS:
2426-87-1
MF:
C15H14O3
Structure:
Chemical Name:
1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
CAS:
17082-61-0
MF:
C10H22O2Si2
Structure:
Chemical Name:
6-BROMOHEXANENITRILE
CAS:
6621-59-6
MF:
C6H10BrN
Structure:
Chemical Name:
3,4,5-Trichloronitrobenzene
CAS:
20098-48-0
MF:
C6H2Cl3NO2
Structure:
Chemical Name:
4-Nitro-1-naphthol
CAS:
605-62-9
MF:
C10H7NO3
Structure:
Chemical Name:
ETHYL HEPTAFLUOROBUTYRATE
CAS:
356-27-4
MF:
C6H5F7O2
Structure:
Chemical Name:
METHIOCARB SULFONE
CAS:
2179-25-1
MF:
C11H15NO4S
Structure:
Chemical Name:
AZEPAN-1-YL-PIPERIDIN-4-YL-METHANONE
CAS:
86542-89-4
MF:
C12H22N2O
Structure:
Chemical Name:
N,N,N',N'-TETRAMETHYL-1,3-BUTANEDIAMINE
CAS:
97-84-7
MF:
C8H20N2
Structure:
Chemical Name:
3-(3-METHYLPHENYL)PROPIONIC ACID
CAS:
3751-48-2
MF:
C10H12O2
Structure:
Chemical Name:
6-NITROPIPERONAL
CAS:
712-97-0
MF:
C8H5NO5
Structure:
Chemical Name:
4-PENTEN-1-YL ACETATE
CAS:
1576-85-8
MF:
C7H12O2
Structure:
Chemical Name:
3-Chloro-4-fluorophenylhydrazine hydrochloride
CAS:
175135-74-7
MF:
C6H7Cl2FN2
Structure:
Chemical Name:
6(5H)-Phenanthridone
CAS:
1015-89-0
MF:
C13H9NO
Structure:
Chemical Name:
1,3-Phenylenediacetonitrile
CAS:
626-22-2
MF:
C10H8N2
Structure:
Chemical Name:
2-(4-FLUOROBENZYLSULFONYL)ACETAMIDOXIME
CAS:
175276-85-4
MF:
C9H11FN2O3S
Structure:
Chemical Name:
2,2'-Bicinchoninic Acid
CAS:
1245-13-2
MF:
C20H12N2O4
Structure:
Chemical Name:
4-BROMOPHENYL ISOTHIOCYANATE
CAS:
1985-12-2
MF:
C7H4BrNS
Structure:
Chemical Name:
2-(BUTYLAMINO)ETHANOL
CAS:
111-75-1
MF:
C6H15NO
Structure:
Chemical Name:
Trimethylolpropane trimethacrylate
CAS:
3290-92-4
MF:
C18H26O6
Structure:
Chemical Name:
2-Amino-4-chloro-5-nitrophenol
CAS:
6358-07-2
MF:
C6H5ClN2O3
Structure:
Chemical Name:
4-TRIMETHYLSILOXY-3-PENTEN-2-ONE
CAS:
13257-81-3
MF:
C8H16O2Si
Structure:
Chemical Name:
3,3',5,5'-TETRACHLORODIPHENYL DISULFIDE
CAS:
137897-99-5
MF:
C12H6Cl4S2
Structure:
Chemical Name:
P-TOLUENESULFONIC ACID 1-BUTYN-3-YL ESTER
CAS:
53487-52-8
MF:
C11H12O3S
Structure:
Chemical Name:
P-XYLYLENEDIPHOSPHONIC ACID TETRAETHYL ESTER
CAS:
4546-04-7
MF:
C16H28O6P2
Structure:
Chemical Name:
ZINC P-TOLUENESULFONATE HYDRATE
CAS:
123334-05-4
MF:
C7H10O4SZn
Structure:
Chemical Name:
Tri-o-cresyl Phosphate
CAS:
78-30-8
MF:
C21H21O4P
Structure:
Chemical Name:
Propargyl p-toluenesulfonate
CAS:
6165-76-0
MF:
C10H10O3S
Structure:
Chemical Name:
1-Bromopinacolone
CAS:
5469-26-1
MF:
C6H11BrO
Structure:
Chemical Name:
Dichlorodiethylsilane
CAS:
1719-53-5
MF:
C4H10Cl2Si
Structure:
Chemical Name:
4-Bromo-2,6-dimethylphenol
CAS:
2374-05-2
MF:
C8H9BrO
Structure:
Chemical Name:
(PHENYLSULFONYL)ACETONITRILE
CAS:
7605-28-9
MF:
C8H7NO2S
Structure:
Chemical Name:
TETRAKIS(TRIMETHYLSILYL)SILANE
CAS:
4098-98-0
MF:
C12H36Si5
Structure:
Chemical Name:
1-(5-Chloro-2-hydroxyphenyl)ethanone
CAS:
1450-74-4
MF:
C8H7ClO2
Structure:
Chemical Name:
2-(Diethylamino)ethyl methacrylate
CAS:
105-16-8
MF:
C10H19NO2
Structure:
Chemical Name:
4,4'-DIBROMO DIPHENYL SULFONE
CAS:
2050-48-8
MF:
C12H8Br2O2S
Structure:
Chemical Name:
Triphenyl(propyl)phosphonium
CAS:
15912-75-1
MF:
C21H22P+
Structure:
Chemical Name:
11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE
CAS:
134179-38-7
MF:
C8H18N4O3
Structure:
Chemical Name:
N-BUTYL-4-METHYLPYRIDINIUM CHLORIDE
CAS:
112400-86-9
MF:
C10H16ClN
Structure:
Chemical Name:
4-(N-Ethyl-N-benzyl)amino benzoaldehyde-1,1-diphenylhydrazone
CAS:
96861-52-8
MF:
C28H27N3
Structure:
Chemical Name:
Poly(hexamethylenebiguanide)hydrochloride
CAS:
32289-58-0
MF:
C10H23N5
Structure:
Chemical Name:
2,2,2-TRIFLUOROETHYL BUTYRATE
CAS:
371-27-7
MF:
C6H9F3O2
Structure:
Chemical Name:
2,3,6-TRICHLOROPHENOL
CAS:
933-75-5
MF:
C6H3Cl3O
Structure:
Chemical Name:
PHENYLSULFONYLACETIC ACID ETHYL ESTER
CAS:
7605-30-3
MF:
C10H12O4S
Structure:
Chemical Name:
(S)-(+)-1,1'-BI-2-NAPHTHYL DI-P-TOLUENESULFONATE
CAS:
128575-35-9
MF:
C34H26O6S2
Structure:
Chemical Name:
9-Anthrracenecarbonitrile
CAS:
1210-12-4
MF:
C15H9N
Structure:
Chemical Name:
2,3-Diaminophenol
CAS:
59649-56-8
MF:
C6H8N2O
Structure:
Chemical Name:
Dicyclohexano-18-crown-6
CAS:
16069-36-6
MF:
C20H36O6
Structure:
Chemical Name:
3-METHYL-2,5-DIHYDROTHIOPHENE-1,1-DIOXIDE
CAS:
1193-10-8
MF:
C5H8O2S
Structure:
Chemical Name:
2,4,6-Trimethylphenol
CAS:
527-60-6
MF:
C9H12O
Structure:
Chemical Name:
2-(2-Methoxyphenoxy)ethyl-4-methylbenzensulfonate
CAS:
137309-88-7
MF:
C16H18O5S
Structure:
Chemical Name:
THIODIGLYCOLIC ACID
CAS:
505-73-7
MF:
C4H6O4S2
Structure:
Chemical Name:
Tripropylene glycol
CAS:
24800-44-0
MF:
C9H20O4
Structure:
Chemical Name:
Diphenyldiethoxysilane
CAS:
2553-19-7
MF:
C16H20O2Si
Structure:
Chemical Name:
trans-3-Hexenoic acid
CAS:
1577-18-0
MF:
C6H10O2
Structure:
Chemical Name:
2-BROMOBENZAMIDE
CAS:
4001-73-4
MF:
C7H6BrNO
Structure:
Chemical Name:
3-FLUOROBENZHYDRAZIDE
CAS:
499-55-8
MF:
C7H7FN2O
Structure:
Chemical Name:
7-Acetoxy-4-methylcoumarin
CAS:
2747-05-9
MF:
C12H10O4
Structure:
Chemical Name:
Tris(trimethylsilyl)phosphate
CAS:
10497-05-9
MF:
C9H27O4PSi3
Structure:
Chemical Name:
3-Bromo-3,3-difluoropropene
CAS:
420-90-6
MF:
C3H3BrF2
Structure:
Chemical Name:
1-(2-Bromoethoxy)-4-nitrobenzene
CAS:
13288-06-7
MF:
C8H8BrNO3
Structure:
Chemical Name:
4-ETHYLTOLUENE
CAS:
622-96-8
MF:
C9H12
Structure:
Chemical Name:
BROMOHYDROQUINONE
CAS:
583-69-7
MF:
C6H5BrO2
Structure:
Chemical Name:
1-Hydroxy-1-cyclopropanecarboxylic acid
CAS:
17994-25-1
MF:
C4H6O3
Structure:
Chemical Name:
PYRIDINE-2-CARBOXALDEHYDE 2-QUINOLYLHYDRAZONE
CAS:
7385-99-1
MF:
C15H12N4
Structure:
Chemical Name:
DIPHENYL PHTHALATE
CAS:
84-62-8
MF:
C20H14O4
Structure:
Chemical Name:
2-METHOXYETHYL CHLOROFORMATE
CAS:
628-12-6
MF:
C4H7ClO3
Structure:
Chemical Name:
1,8-DICHLOROANTHRAQUINONE
CAS:
82-43-9
MF:
C14H6Cl2O2
Structure:
Chemical Name:
3-(Trifluoromethyl)phenylacetone
CAS:
21906-39-8
MF:
C10H9F3O
Structure:
Chemical Name:
4'-Heptyl-4-biphenylcarbonitrile
CAS:
41122-71-8
MF:
C20H23N
Structure:
Chemical Name:
2,2,2-TRIFLUOROETHYL FORMATE
CAS:
32042-38-9
MF:
C3H3F3O2
Structure:
Chemical Name:
TRIMETHYLSILYLMETHANETHIOL
CAS:
18165-76-9
MF:
C4H12SSi
Structure:
Chemical Name:
2,5-Dimethoxytoluene
CAS:
24599-58-4
MF:
C9H12O2
Structure:
Chemical Name:
4-Pentyloxy-[1,1'-biphenyl]-4'-carbonitrile
CAS:
52364-71-3
MF:
C18H19NO
Structure:
Chemical Name:
ALLYLTRIETHOXYSILANE
CAS:
2550-04-1
MF:
C9H20O3Si
Structure:
Chemical Name:
2-Diazo-1-naphthol-4-sulfonate
CAS:
64173-96-2
MF:
C10H7N2O4S-
Structure:
Chemical Name:
5-Nitrobenzothiazole-2-thiol
CAS:
58759-63-0
MF:
C7H4N2O2S2
Structure:
Chemical Name:
Isopentyl ether
CAS:
544-01-4
MF:
C10H22O
Structure:
Chemical Name:
(2-Chlorophenyl)phenyl-methanone
CAS:
5162-03-8
MF:
C13H9ClO
Structure:
Chemical Name:
3-METHOXYBENZOYL CHLORIDE
CAS:
1711-05-3
MF:
C8H7ClO2
Structure:
Chemical Name:
N-(Hydroxymethyl)benzamide
CAS:
6282-02-6
MF:
C8H9NO2
Structure:
Chemical Name:
(S)-(-)-2,2'-Dimethoxy-1,1'-binaphthalene
CAS:
75640-87-8
MF:
C22H18O2
Structure:
Chemical Name:
PLUMBAGIN
CAS:
481-42-5
MF:
C11H8O3
Structure:
Chemical Name:
Indazole-4-boronic acid, hydrochloride
CAS:
1023595-17-6
MF:
C7H7BN2O2
Structure:
Chemical Name:
Trityl azide
CAS:
14309-25-2
MF:
C19H15N3