Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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Organic reagents

Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.

After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.

8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.

Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.

Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.

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Structure:
Chemical Name:
3,5-dimethylmorpholine-4-carboxamidine
CAS:
108641-44-7
MF:
C7H15N3O
Structure:
Chemical Name:
4-TERT-AMYLCYCLOHEXANOL
CAS:
5349-51-9
MF:
C11H22O
Structure:
Chemical Name:
AMINOOXY-N-BUTANE HYDROCHLORIDE
CAS:
5622-77-5
MF:
C4H11NO
Structure:
Chemical Name:
N-Ethyl-Pentylamine
CAS:
17839-26-8
MF:
C7H17N
Structure:
Chemical Name:
CPPO
MF:
C26H24Cl6O8
Structure:
Chemical Name:
DIMETHYLAMINOACETYL CHLORIDE HYDROCHLORIDE
CAS:
60853-81-8
MF:
C4H9Cl2NO
Structure:
Chemical Name:
4-BROMO-2-FLUOROPHENYL ISOCYANATE
CAS:
88112-75-8
MF:
C7H3BrFNO
Structure:
Chemical Name:
SALICYLIDENE SALICYLHYDRAZIDE
CAS:
3232-36-8
MF:
C14H12N2O3
Structure:
Chemical Name:
3-(1H-IMIDAZOL-2-YL)-PROPIONIC ACID
CAS:
178388-79-9
MF:
C6H8N2O2
Structure:
Chemical Name:
4-PENTYLBENZOYL CHLORIDE
CAS:
49763-65-7
MF:
C12H15ClO
Structure:
Chemical Name:
4-Methylbenzyl isocyanate
CAS:
56651-57-1
MF:
C9H9NO
Structure:
Chemical Name:
DL-4-HYDROXY-3-METHOXYMANDELIC ACID
CAS:
2394-20-9
MF:
C9H10O5
Structure:
Chemical Name:
3-BENZOYLBENZOIC ACID
CAS:
579-18-0
MF:
C14H10O3
Structure:
Chemical Name:
N-[4-(Morpholin-4-yl)phenyl]guanidine
CAS:
247234-41-9
MF:
C11H16N4O
Structure:
Chemical Name:
p-Nitrophenoxyamine
CAS:
33543-55-4
MF:
C6H6N2O3
Structure:
Chemical Name:
2-CYANOACETANILIDE
CAS:
621-03-4
MF:
C9H8N2O
Structure:
Chemical Name:
3,3-DIETHOXY-1-PROPANOL
CAS:
16777-87-0
MF:
C7H16O3
Structure:
Chemical Name:
METHYLTRIALLYLSILANE
CAS:
1112-91-0
MF:
C10H18Si
Structure:
Chemical Name:
3-CHLORO-1-PROPANETHIOL
CAS:
17481-19-5
MF:
C3H7ClS
Structure:
Chemical Name:
3-PHENOXYBENZENEBORONIC ACID
CAS:
221006-66-2
MF:
C12H11BO3
Structure:
Chemical Name:
Diisooctyl maleate
CAS:
1330-76-3
MF:
C20H36O4
Structure:
Chemical Name:
1,4-Bis(4-cyanostyryl)benzene
CAS:
13001-40-6
MF:
C24H16N2
Structure:
Chemical Name:
(R)-(S)-JOSIPHOS
CAS:
155806-35-2
MF:
C36H44FeP210*
Structure:
Chemical Name:
4-MERCAPTOPHENYLACETIC ACID
CAS:
39161-84-7
MF:
C8H8O2S
Structure:
Chemical Name:
BARIUM DINONYLNAPHTHALENESULFONATE
CAS:
25619-56-1
MF:
C56H86BaO6S2
Structure:
Chemical Name:
CIS-1,8-DIAMINO-P-METHANE
CAS:
54166-24-4
MF:
C10H22N2
Structure:
Chemical Name:
6-METHYLCHROMONE-2-CARBOXYLIC ACID
CAS:
5006-44-0
MF:
C11H8O4
Structure:
Chemical Name:
4-Phenoxy-2',2'-dichloroacetophenone
CAS:
59867-68-4
MF:
C14H10Cl2O2
Structure:
Chemical Name:
Di(propylene glycol) methyl ether acetate
CAS:
88917-22-0
MF:
C9H18O4
Structure:
Chemical Name:
4,4-DIMETHYL-2-PENTANONE
CAS:
590-50-1
MF:
C7H14O
Structure:
Chemical Name:
3-NITRO-2-BUTANOL
CAS:
6270-16-2
MF:
C4H9NO3
Structure:
Chemical Name:
3-AMINO-1-PHENYL-PROPAN-1-OL
CAS:
5053-63-4
MF:
C9H13NO
Structure:
Chemical Name:
METHYL (2S)-GLYCIDATE
CAS:
118712-39-3
MF:
C4H6O3
Structure:
Chemical Name:
1,1'-FERROCENEDIMETHANOL
CAS:
1291-48-1
MF:
C12H14FeO210*
Structure:
Chemical Name:
2,5-DIMETHYLPHENETHYLAMINE
CAS:
23068-44-2
MF:
C10H15N
Structure:
Chemical Name:
DIDODECYL PHTHALATE
CAS:
2432-90-8
MF:
C32H54O4
Structure:
Chemical Name:
2-ETHYLSULFINYLPHENYLBORONIC ACID
CAS:
1072952-11-4
MF:
C8H11BO3S
Structure:
Chemical Name:
2',5'-DIHYDROXYPROPIOPHENONE
CAS:
938-46-5
MF:
C9H10O3
Structure:
Chemical Name:
DIBUTYLBORON TRIFLUOROMETHANESULFONATE
CAS:
60669-69-4
MF:
C9H18BF3O3S
Structure:
Chemical Name:
3,3'-THIODIPROPANOL
CAS:
10595-09-2
MF:
C6H14O2S
Structure:
Chemical Name:
4-BUTYLBENZONITRILE
CAS:
20651-73-4
MF:
C11H13N
Structure:
Chemical Name:
TRIHEXYL(TETRADECYL)PHOSPHONIUM DECANOATE
CAS:
465527-65-5
MF:
C42H87O2P
Structure:
Chemical Name:
3-CYANOMETHYLPHENYLBORONIC ACID
CAS:
220616-39-7
MF:
C8H8BNO2
Structure:
Chemical Name:
(S)-(+)-2-PHENYLBUTYRIC ACID
CAS:
4286-15-1
MF:
C10H12O2
Structure:
Chemical Name:
ALPHA-HYDROXYHIPPURIC ACID
CAS:
16555-77-4
MF:
C9H9NO4
Structure:
Chemical Name:
5-CHLORO-N-METHYL-2-NITROBENZENAMINE
CAS:
35966-84-8
MF:
C7H7ClN2O2
Structure:
Chemical Name:
1-(P-TOLYL)-1-CYCLOPENTANECARBOXYLIC ACID
CAS:
80789-75-9
MF:
C13H16O2
Structure:
Chemical Name:
4-(METHANESULFONYLAMINO)PHENYLACETIC ACID
CAS:
56205-88-0
MF:
C9H11NO4S
Structure:
Chemical Name:
PHENYLGLYOXAL MONOHYDRATE
CAS:
1075-06-5
MF:
C8H8O3
Structure:
Chemical Name:
ETHYLENEBIS(ISOTHIOURONIUM BROMIDE)
CAS:
6943-65-3
MF:
C4H12Br2N4S2
Structure:
Chemical Name:
TRIPROPYLENE GLYCOL MONOMETHYL ETHER
CAS:
20324-33-8
MF:
C10H22O4
Structure:
Chemical Name:
[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-2-THIOL
MF:
C5H4N4S
Structure:
Chemical Name:
FORMALDOXIME TRIMER HYDROCHLORIDE
CAS:
62479-72-5
MF:
C3H10ClN3O3
Structure:
Chemical Name:
2-(METHOXYCARBONYL)PHENYL ISOCYANATE
CAS:
1793-07-3
MF:
C9H7NO3
Structure:
Chemical Name:
4-Nonylphenylboronic acid
CAS:
256383-45-6
MF:
C15H25BO2
Structure:
Chemical Name:
1-Phenylvinylboronic acid
CAS:
14900-39-1
MF:
C8H9BO2
Structure:
Chemical Name:
4-VINYLBENZYL ACETATE
CAS:
1592-12-7
MF:
C11H12O2
Structure:
Chemical Name:
3-(3-CHLORO-PHENYL)-PROPIONALDEHYDE
CAS:
136415-83-3
MF:
C9H9ClO
Structure:
Chemical Name:
3-ETHYLSULFINYLPHENYLBORONIC ACID
CAS:
1072952-07-8
MF:
C8H11BO3S
Structure:
Chemical Name:
11-MERCAPTOUNDECANOIC ACID
CAS:
71310-21-9
MF:
C11H22O2S
Structure:
Chemical Name:
O-TOLYL-METHANESULFONYL CHLORIDE
CAS:
92614-55-6
MF:
C8H9ClO2S
Structure:
Chemical Name:
N-BUTYL-4-METHYLPYRIDINIUM TETRAFLUOROBORATE
CAS:
343952-33-0
MF:
C10H16BF4N
Structure:
Chemical Name:
4-(TRIFLUOROMETHOXY)PHENYL ISOTHIOCYANATE
CAS:
64285-95-6
MF:
C8H4F3NOS
Structure:
Chemical Name:
(+)-ISOPINOCAMPHEYLBORANE TMEDA COMPLEX
CAS:
68297-74-5
MF:
2C10H19B.C6H16N2
Structure:
Chemical Name:
6-QUINOLINYL TRIFLUOROMETHANESULFONATE
CAS:
173089-80-0
MF:
C10H6F3NO3S
Structure:
Chemical Name:
METHYL 2-CHLOROBENZOYLACETATE, 97
CAS:
205985-98-4
MF:
C10H9ClO3
Structure:
Chemical Name:
POTASSIUM INDIGOTETRASULFONATE
CAS:
67627-19-4
MF:
C16H11KN2O14S4
Structure:
Chemical Name:
6-NITROPIPERONYL ALCOHOL
CAS:
15341-08-9
MF:
C8H7NO5
Structure:
Chemical Name:
1-(2-BROMOETHOXY)-2-NITROBENZENE
CAS:
18800-37-8
MF:
C8H8BrNO3
Structure:
Chemical Name:
MAGNESIUM HYPOPHOSPHITE HEXAHYDRATE
CAS:
26264-58-4
MF:
Mg(H2PO2)2.6H2O
Structure:
Chemical Name:
SODIUM CYCLOHEXANEBUTYRATE
CAS:
61886-29-1
MF:
C10H17NaO2
Structure:
Chemical Name:
PHENOXYACETAMIDE
CAS:
621-88-5
MF:
C8H9NO2
Structure:
Chemical Name:
4-NITROPHENYL PHENYL ETHER
CAS:
620-88-2
MF:
C12H9NO3
Structure:
Chemical Name:
2-DIMETHYLAMINOBENZOIC ACID
CAS:
610-16-2
MF:
C9H11NO2
Structure:
Chemical Name:
1,3-BENZENEDITHIOL
CAS:
626-04-0
MF:
C6H6S2
Structure:
Chemical Name:
1,3-DIBENZOYLOXYBENZENE
CAS:
94-01-9
MF:
C20H14O4
Structure:
Chemical Name:
DI-SEC-BUTYL SULFIDE
CAS:
626-26-6
MF:
C8H18S
Structure:
Chemical Name:
1-ALLYL-3-METHYLIMIDAZOLIUM CHLORIDE
CAS:
65039-10-3
MF:
C7H11ClN2
Structure:
Chemical Name:
2,5-DICHLOROHYDROQUINONE
CAS:
824-69-1
MF:
C6H4Cl2O2
Structure:
Chemical Name:
TRI-SEC-BUTYLBORANE
CAS:
1113-78-6
MF:
C12H27B
Structure:
Chemical Name:
3-(METHANESULFONYLAMINO)BENZOIC ACID
CAS:
28547-13-9
MF:
C8H9NO4S
Structure:
Chemical Name:
(ETHYLTHIO)TRIMETHYLSILANE
CAS:
5573-62-6
MF:
C5H14SSi
Structure:
Chemical Name:
BENZIL MONOHYDRAZONE
CAS:
5344-88-7
MF:
C14H12N2O
Structure:
Chemical Name:
1-DECYL-3-METHYLIMIDAZOLIUM TETRAFLUOROBORATE
CAS:
244193-56-4
MF:
C14H27BF4N2
Structure:
Chemical Name:
4-BORONOBENZENESULFONIC ACID
CAS:
913836-00-7
MF:
C6H7BO5S
Structure:
Chemical Name:
Ammonium anthraquinone-1-sulfonate
CAS:
55812-59-4
MF:
C14H11NO5S
Structure:
Chemical Name:
benzyl octyl phthalate
CAS:
1248-43-7
MF:
C23H28O4
Structure:
Chemical Name:
3-mercaptopropiononitrile
CAS:
1001-58-7
MF:
C3H5NS
Structure:
Chemical Name:
CYCLOBUTYLBORONIC ACID
CAS:
849052-26-2
MF:
C4H9BO2
Structure:
Chemical Name:
3-METHYL-BENZAMIDINE
CAS:
18465-28-6
MF:
C8H10N2
Structure:
Chemical Name:
2,4-DINITROPHENYLTAURINE SODIUM SALT
CAS:
23928-04-3
MF:
C8H8N3NaO7S
Structure:
Chemical Name:
1-(methylthio)ethanethiol
CAS:
31331-53-0
MF:
C3H8S2
Structure:
Chemical Name:
4-ETHOXYSTYRENE
CAS:
5459-40-5
MF:
C10H12O
Structure:
Chemical Name:
4-chlorophenylhydroxylamine
CAS:
823-86-9
MF:
C6H6ClNO
Structure:
Chemical Name:
5-(2-CHLORO-PHENYL)-[1,3,4]OXADIAZOLE-2-THIOL
CAS:
23766-27-0
MF:
C8H5ClN2OS
Structure:
Chemical Name:
4-FLUORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE
CAS:
139057-86-6
MF:
C8H3F4NO
Structure:
Chemical Name:
3,4-DIBROMOBENZENESULFONYL CHLORIDE
CAS:
81903-80-2
MF:
C6H3Br2ClO2S
Structure:
Chemical Name:
3-(Trifluoromethoxy)benzimidamide
CAS:
791566-24-0
MF:
C8H7F3N2O
Structure:
Chemical Name:
Potassium tert-butoxymethyltrifluoroborate
CAS:
910251-10-4
MF:
C5H11BF3O.K
Structure:
Chemical Name:
METHYL-(5-[N-METHYL-N-PHENYLAMINO]-2,4-PENTADIENYLIDENE)-PHENYLAMMONIUM CHLORIDE
CAS:
13984-07-1
MF:
C19H21ClN2