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Antihistamines

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Antihistamines are a class of drugs that reversibly block histamine receptors and competitively block histamine binding to receptors, thereby exhibiting antihistamine effects. There are two types of histamine receptors: H1 and H2, and antihistamines are also separated into the corresponding two categories: H1 receptor blockers, such as anti-allergy diphenhydramine; H2 receptor blockers, such as cimetidine which inhibits the secretion of gastric acid.
Antihistamines are widely used in clinical applications, mainly for:
① skin and mucous membrane allergic disease;
② bronchial asthma;
③ motion sickness and vomiting;
④ sedation and hypnosis.
There are no clear guidelines for the safe use of antihistamines in pregnant women. Generally believed, these drugs have no obvious teratogenic effects on the fetus, but the application within 2 weeks before delivery may lead to the formation of posterior fibrous histiocytoma.

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Structure:
Chemical Name:
Olopatadine
CAS:
113806-05-6
MF:
C21H23NO3
Structure:
Chemical Name:
Desloratadine
CAS:
100643-71-8
MF:
C19H19ClN2
Structure:
Chemical Name:
Fexofenadine
CAS:
83799-24-0
MF:
C32H39NO4
Structure:
Chemical Name:
Loratadine
CAS:
79794-75-5
MF:
C22H23ClN2O2
Structure:
Chemical Name:
Diphenhydramine Hydrochloride
CAS:
147-24-0
MF:
C17H22ClNO
Structure:
Chemical Name:
Ebastine
CAS:
90729-43-4
MF:
C32H39NO2
Structure:
Chemical Name:
Chlorphenamine maleate
CAS:
113-92-8
MF:
C20H23ClN2O4
Structure:
Chemical Name:
Roxatidine acetate
CAS:
78628-28-1
MF:
C19H28N2O4
Structure:
Chemical Name:
Cetirizine dihydrochloride
CAS:
83881-52-1
MF:
C21H26Cl2N2O3
Chemical Name:
"Desloratadine Citrate Disodium"
Structure:
Chemical Name:
Levocetirizine dihydrochloride
CAS:
130018-87-0
MF:
C21H27Cl3N2O3
Structure:
Chemical Name:
Azelastine hydrochloride
CAS:
79307-93-0
MF:
C22H25Cl2N3O
Structure:
Chemical Name:
Cyproheptadine hydrochloride sesquihydrate
CAS:
41354-29-4
MF:
C21H24ClNO
Structure:
Chemical Name:
Clemastine fumarate
CAS:
14976-57-9
MF:
C25H30ClNO5
Structure:
Chemical Name:
Promethazine hydrochloride
CAS:
58-33-3
MF:
C17H21ClN2S
Structure:
Chemical Name:
Epinastine
CAS:
80012-43-7
MF:
C16H15N3
Structure:
Chemical Name:
Brompheniramine hydrogen maleate
CAS:
980-71-2
MF:
C20H23BrN2O4
Structure:
Chemical Name:
Astemizole
CAS:
68844-77-9
MF:
C28H31FN4O
Structure:
Chemical Name:
Etymemazine
CAS:
523-54-6
MF:
C20H26N2S
Structure:
Chemical Name:
(S)-Azelastine Hydrochloride
CAS:
153408-27-6
MF:
C22H24ClN3O·HCl
Structure:
Chemical Name:
Trimeprazine
CAS:
84-96-8
MF:
C18H22N2S
Structure:
Chemical Name:
DIMETHINDENE
CAS:
5636-83-9
MF:
C20H24N2
Structure:
Chemical Name:
deptropine
CAS:
604-51-3
MF:
C23H27NO
Structure:
Chemical Name:
Brompheniramine
CAS:
86-22-6
MF:
C16H19BrN2
Structure:
Chemical Name:
Meclizine Dihydrochloride Monohydrate
CAS:
31884-77-2
MF:
C25H27ClN2.2ClH.H2O
Structure:
Chemical Name:
thonzylamine
CAS:
91-85-0
MF:
C16H22N4O
Structure:
Chemical Name:
Azatadine
CAS:
3964-81-6
MF:
C20H22N2
Structure:
Chemical Name:
Meclozine
CAS:
569-65-3
MF:
C25H27ClN2
Structure:
Chemical Name:
Pheniramine
CAS:
86-21-5
MF:
C16H20N2
Structure:
Chemical Name:
Oxatomide
CAS:
60607-34-3
MF:
C27H30N4O
Structure:
Chemical Name:
CLEMASTINE FUMARATE
CAS:
15686-51-8
MF:
C21H26ClNO
Structure:
Chemical Name:
Cetirizine
CAS:
83881-51-0
MF:
C21H25ClN2O3
Structure:
Chemical Name:
AZATADINE MALEATE (200 MG)
CAS:
3978-86-7
MF:
C28H30N2O8
Structure:
Chemical Name:
PYRILAMINE MALEATE
CAS:
59-33-6
MF:
C21H27N3O5
Structure:
Chemical Name:
CARBINOXAMINE MALEATE SALT
CAS:
3505-38-2
MF:
C20H23ClN2O5
Structure:
Chemical Name:
Dimenhydrinate
CAS:
523-87-5
MF:
C17H21NO.C7H7ClN4O2
Structure:
Chemical Name:
EPINASTINE HYDROCHLORIDE
CAS:
108929-04-0
MF:
C16H16ClN3
Structure:
Chemical Name:
MEQUITAZINE
CAS:
29216-28-2
MF:
C20H22N2S
Structure:
Chemical Name:
Cloperastine hydrochloride
CAS:
14984-68-0
MF:
C20H25Cl2NO
Structure:
Chemical Name:
Diphenhydramine
CAS:
58-73-1
MF:
C17H21NO
Structure:
Chemical Name:
Setastine
CAS:
64294-95-7
MF:
C22H28ClNO
Structure:
Chemical Name:
Triprolidine hydrochloride
CAS:
6138-79-0
MF:
C19H23ClN2
Structure:
Chemical Name:
Azelastine
CAS:
58581-89-8
MF:
C22H24ClN3O
Structure:
Chemical Name:
DIMETHINDENE MALEATE
CAS:
3614-69-5
MF:
C24H28N2O4
Structure:
Chemical Name:
TRIPELENNAMINE HYDROCHLORIDE
CAS:
154-69-8
MF:
C16H22ClN3
Structure:
Chemical Name:
Acrivastine
CAS:
87848-99-5
MF:
C22H24N2O2
Structure:
Chemical Name:
Terfenadine
CAS:
50679-08-8
MF:
C32H41NO2
Structure:
Chemical Name:
Triprolidine
CAS:
486-12-4
MF:
C19H22N2
Chemical Name:
Levoceitrizine Hcl
Structure:
Chemical Name:
Epinastine hydrochloride
CAS:
80012-44-8
MF:
C16H16ClN3
Structure:
Chemical Name:
Decloxizine
CAS:
3733-63-9
MF:
C21H28N2O2
Structure:
Chemical Name:
Meclizine dihydrochloride
CAS:
1104-22-9
MF:
C25H29Cl3N2
Structure:
Chemical Name:
Doxylamine succinate
CAS:
562-10-7
MF:
C21H28N2O5
Structure:
Chemical Name:
Pheniramine maleate
CAS:
132-20-7
MF:
C20H24N2O4
Chemical Name:
Histapyrrodine
Structure:
Chemical Name:
phenyltoloxamine
CAS:
92-12-6
MF:
C17H21NO
Chemical Name:
LODOXAMIDE
Structure:
Chemical Name:
tolpropamine
CAS:
5632-44-0
MF:
C18H23N
Chemical Name:
Clemastine
Structure:
Chemical Name:
Hydroxydiethylphenamine
CAS:
13073-96-6
MF:
C21H28N2O2.2ClH
Structure:
Chemical Name:
LEVOCABASTINE
CAS:
79516-68-0
MF:
C26H29FN2O2
Structure:
Chemical Name:
CLOPERASTINE
CAS:
3703-76-2
MF:
C20H24ClNO
Structure:
Chemical Name:
CYPROHEPTADINE HYDROCHLORIDE
CAS:
969-33-5
MF:
C21H21N.ClH
Structure:
Chemical Name:
Dimetotiazine
CAS:
7456-24-8
MF:
C19H25N3O2S2
Structure:
Chemical Name:
phenindamine
CAS:
82-88-2
MF:
C19H19N
Structure:
Chemical Name:
Chloropyrilene
CAS:
148-65-2
MF:
C14H18ClN3S
Chemical Name:
Diphenazoline
Structure:
Chemical Name:
BAMIPINE
CAS:
4945-47-5
MF:
C19H24N2
Chemical Name:
tolpropamine hydrochloride
CAS:
3339-11-5
MF:
C18H23N.ClH
Chemical Name:
Buclizine
Chemical Name:
Chlorcylizine
Structure:
Chemical Name:
Diphenhydramine citrate
CAS:
88637-37-0
MF:
C23H29NO8
Structure:
Chemical Name:
carbinoxamine
CAS:
486-16-8
MF:
C16H19ClN2O
Structure:
Chemical Name:
promethazine teoclate
CAS:
17693-51-5
MF:
C24H27ClN6O2S
Chemical Name:
Homochlorcyclizine
Structure:
Chemical Name:
Phenyltoloxamine citrate
CAS:
1176-08-5
MF:
C23H29NO8
Structure:
Chemical Name:
Chloropyramine
CAS:
59-32-5
MF:
C16H20ClN3
Structure:
Chemical Name:
DIOXOPROMETHAZINE
MF:
C17H20N2O2S
Structure:
Chemical Name:
Tripelennamine
CAS:
91-81-6
MF:
C16H21N3
Chemical Name:
Isothipendyl
Structure:
Chemical Name:
Cetoxime
CAS:
25394-78-9
MF:
C15H17N3O
Structure:
Chemical Name:
DEXBROMPHENIRAMINE
CAS:
132-21-8
MF:
C16H19BrN2
Structure:
Chemical Name:
DOXYLAMINE
CAS:
469-21-6
MF:
C17H22N2O
Chemical Name:
Clemizole
Chemical Name:
Embramine
Structure:
Chemical Name:
(R)-Azelastine Hydrochloride
CAS:
153408-28-7
MF:
C22H24ClN3O·HCl
Structure:
Chemical Name:
PYRILAMINE
CAS:
91-84-9
MF:
C17H23N3O
Structure:
Chemical Name:
propiomazine
CAS:
362-29-8
MF:
C20H24N2OS
Structure:
Chemical Name:
Dexchlorpheniramine Maleate
CAS:
2438-32-6
MF:
C20H23ClN2O4
Chemical Name:
Decloxizin HCL CP2000
Structure:
Chemical Name:
DIOXOPROMETHAZINE HCL
CAS:
13754-56-8
MF:
C17H20N2O2S
Chemical Name:
Cyclizine
Structure:
Chemical Name:
HexanitrodiphenylaMine
CAS:
131-73-7
MF:
C12H5N7O12
Structure:
Chemical Name:
DEXCHLORPHENIRAMINE
CAS:
25523-97-1
MF:
C16H19ClN2
Structure:
Chemical Name:
PROMETHAZINE
CAS:
60-87-7
MF:
C17H20N2S
Structure:
Chemical Name:
N-2-(4-bromobenzhydryloxy)ethyldimethylamine
CAS:
118-23-0
MF:
C17H20BrNO
Structure:
Chemical Name:
thiazinamium metilsulfate
CAS:
58-34-4
MF:
C19H26N2O4S2